Diabetes

“We start seeing the likelihood you develop diabetes in our data, hypertension. We are becoming a medical device for sleep apnea.”

“We will see less and lesser number of people going into diabetes, hypertension, or cardiac issues, which means lesser pills, right? So, the biggest change I see is that if we are, if we succeed, then the sales of pharma should be less.”

“Alzheimer's, cardiovascular disease, Diabetes, obesity, that these are all symptoms of unhealthy skeletal muscle”

“So we did that with Manjaro and showed a 93% reduction in conversion from pre-diabetes to diabetes.”

“An uncontrolled diabetic costs about 1600 dollars a month. A controlled diabetic can get down to 900 dollars a month, a 700 dollar opportunity.”

“And we just clinically validated the first liquid biopsy test that can identify diabetes two years before you're symptomatic.”

“But figuring out, I feel like there's some athletic adaptation that would be cool, but they, for people who don't have diabetes, I'm less convinced.”

“We just read that study out with Manjaro, which showed that three years on our drug, 94% fewer new diagnosis of outright diabetes.”

“You're four times more likely to be suicidal or depressed if you have diabetes as a kid, right?”

“Nine out of 10 killers of Americans are foodborne illnesses. I mean, we can dance around it. It's just that simple. Like, you would wipe out heart disease, diabetes, kidney disease, respiratory illness, COVID deaths even, if you got our country metabolically m…”

“We can see what's happened in China, where almost 40 years ago, no one had diabetes, and now they have the most people with diabetes in the world.”

“To put that in more real numbers, that means that even by 1980, with all the advances, it took one million animals annually for 30,000 diabetes patients.”

“Like an Indian person living in North America, right? So we have the same exact like upbringing, whatever, is anywhere between four to six times more likely to have heart disease, diabetes, like it's just, it's real bad.”

“You look at these emerging economies, and as GDP cranks, the first thing that happens is heart disease cranks up, and diabetes cranks up”

“You start with fifty million, for diabetes go up to as many as one hundred fifty million people who are diabetic or pre-diabetic, right?”

“And thankfully, there's a lot of populations out there that are still indigenous people, and they live the way that we lived 10,000 years ago, or even a thousand years ago. And they have none. And by the way, many of these indigenous peoples are in every conti…”

“If you stop a rat from sleeping for just two weeks, it will develop diabetes.”

“It translates into depression, anxiety, heart disease, diabetes. They're all metabolic illnesses that come from a debt, running a deficit in your body budget.”

“Personally love when I can have an insight and I can do it in four or five or six stocks. So I might be able to do it in a big company. If you go back over a decade, if implementing a bet on diabetes, you could do it with big companies, you could do it with sm…”

“About a third of people with diabetes don't realize they have it. About a fifth of people with hypertension. For AFib, it's 30 or 40%. For sleep apnea, it's like 80%.”

“Even if we came up with a drug that we thought slowed aging tomorrow, and I thought it would be wonderful for diabetes, I probably wouldn't want to go out and pay for a diabetes trial, right? That's a very competitive space. You need a huge, expensive trial wi…”

“All the companies that we invest in have drugs that have worked not just in kind of mouse models of Alzheimer's typically, but also diabetes and heart disease, and kind of typically the pathways that we invest in have been tested in and work in almost every Ag…”

“Two hundred and fifty billion dollars spent on diabetes and its related costs in 2012.”

“At the end of the day, healthcare is an amazing business that really effectively monetizes illness, and I used to always say, you know, if I successfully get you to never be diabetic, No one makes money. But if you do become diabetic, there's all kinds of ways…”

“In the U.S., and according to the Centers for Disease Control in the U.S., since the late 19 fifties, diabetes prevalence has increased 700%.”

“And you find out, for instance, in the U.S. That diabetes rates, ah, in, were virtually nonexistent, even though it was a very, a relatively easy disease to diagnose You saw very little sign of it pre-eighteen 50, and even, for the most part, pre-eighteen seve…”

“Obesity and diabetes cost, the healthcare system in the U.S., the estimate is a billion dollars in direct medical costs a day.”

“In the insurance space, it's a very underserved community.”