Atallah: No single layer can capture all AI memory context
“I do think that like, it's impossible for one layer to capture all valuable memory because the apps own so much important context that the model labs don't have. And they, the model labs in order to get this to work, they'll have to incentivize the apps to, li…”
Walling: More apps being built will not lead to more companies
“More apps getting built is not going to mean more companies getting built. Because those are two different things.”
Arora: Companies will cut G&A headcount by half within three years
“My rule of thumb is that in the next three years, we'll probably have half the people in GNA type activities in companies. Things like marketing, things like finance, things like HR, because there's a lot of process management there, and a lot of process manag…”
Arora: SaaS applications will give way to opinionated AI applications
“SaaS applications will give way to AI applications, the difference being SaaS applications have no opinion, AI applications will have opinions. That's a fundamental rethink we need from a workflow perspective.”
Balaban: Modern AI applications are far less latency-sensitive than legacy cloud apps
“The old school traditional legacy cloud business was so latency focused because of some of the applications, but this new fleet of AI applications are far less latency sensitive.”
Sankar: Most compelling AI applications are built by military personnel
“The most compelling AI applications I'm seeing across commercial or, you know, so private sector or public sector are being built by these green suitors.”
McKelvey: Unclear Monetization Makes AI Valuations Hard to Understand
“The AI applications are so incredibly powerful and amazing, but because they can do so much, and it's not yet clear exactly how to monetize them, it is a bit confusing to understand how will they be evaluated, you know.”
George: Enterprise Rules and Integration Drive AI Application Retention
“The more stuff that gets integrated and the more company specific like kind of rules built around the model stuff you have, the stickier it's gonna be.”
Rampell: AI applications need vertical operating systems to prevent churn
“I need to build some kind of system of record for you, some kind of vertical operating system for you so that you can't just go switch out for the cheaper player.”
Horowitz: AI Foundation Models Cannot Subsume Application Complexity
“Right now, currently, I would say that the complexity of the application itself is very high and is not subsumed in the foundation model. And so I think these things are not as straightforward as they appear and the benchmarks can be misleading.”
Underlying LLMs are technically completely uninvolved in the Model Context Protocol
“MCP is a protocol between the AI application and like servers, right? So the model is actually technically not involved in MCP.”
Most AI applications will eventually adopt sandboxed execution environments for code
“And I think you will see evolutions as we're getting better of like how we use these models and the infrastructure around it gets a bit more mature. And you suddenly can assume that most model like AI applications will have some form of like Sandboxing for exe…”
Ghodsi: Most AI economic value will accrue to applications
“But I do think most of the value will accrue to the apps. So it's kind of, and I think that's common sense. It's just, I just don't know which apps.”
Xanthos: AI products must integrate institutional tribal knowledge to succeed
“I do believe that to be very successful, and I've seen many examples of that, you need to incorporate a lot of the knowledge, specifics, the tribal knowledge or institutional knowledge into, let's say, the product or the model to be able to be highly effective…”
Andrusko: The Prompt Box Will Die as Primary AI Interface by 2026
“My big idea for 2026 is the death of the prompt box as the primary user interface for AI applications. The next wave of apps will require way less prompting. They'll observe what you're doing and intervene proactively with actions for you to review.”
Perret: AI agents will be the primary mortgage application method by 2027
“And there are a few interesting use cases, but you know, fast forward two years and the way that you get a mortgage is going to be talking to your AI application.”
Chakkarapani: Zuora evaluated 50+ AI apps in three months, deploying 12
“In the past three months we have almost put in almost, like, 50 plus applications through this process, and 12 of them have already gone into production.”
O'Driscoll: AI Software Automates Actual Work Rather Than Just Updating UIs
“Salesforce was rebuild Siebel in the cloud, and it was fun, and we made a lot of money, but you're right, somewhat boring. What is really exciting now is you're not just talking about rebuild Salesforce exactly the same, but with a slightly modern UI. You are …”
Heller: AI application TAM is 1,000x larger when capturing labor budgets
“Today, the actual amount of money that we already know people and companies are willing to spend is the combined salaries of all the people they're currently paying to do the job. And that number is like a thousand X bigger. You pay 20 dollars a month to solve…”
Effective Enterprise AI Apps With FDEs Cost $30K to $100K Annually
“These apps that need to be trained with forward deployed engineers and work. I don't think very many of them are less than 30 or 50,000 dollars a year. And a lot of them actually try to kind of have a price point that's approaching a hundred K like 60 K a year…”
Darisi: AI workflow layers lack stickiness unless they own the underlying record
“You can actually build an application just a layer on top of a legacy systems where it can able to give you immense value, but you will be replaced because a new tool comes. So it's like there is no stickiness to it, right? So you are actually as good as a wor…”
Lingelbach: Niche AI apps can reach hundreds of millions in revenue
“There applications that maybe aren't wildly popular, but they're so popular amongst a passionate group of segments, these companies can scale to like hundreds of millions of revenue.”
Trillions in App Value Remains Even If AI Models Stop Improving
“That even if you froze the model capabilities, there's trillions and trillions of dollars of applications just waiting to be discovered here.”
The Bar for AI Product-Market Fit Has Risen Dramatically
“The bar for what product market fit and what an effective wedge looks like has gone up in AI because you've just seen explosive growth for companies when they do have them.”
Gerstner: AI Model Layer Is Commoditizing, Value Accrues to Applications
“What that tells me is the model layers being increasingly commoditized. And that there's not going to be a lot of intrinsic value in, in, in that intelligence layer, that operating layer. You're going to have to build applications that guys like Bill Gurley an…”
Bornstein: Simple AI wrapper startups no longer exist
“And like, we're like pretty clear past the sort of rapper phase. Like, I don't think there are any rappers anymore. Like, Building good products with AI is really hard, and the founders doing it now have, like, really good kind of intuition for how to do it.”
Conrad: Building AI governance and pipelines is harder than building applications
“What I think is going to be very durable with AI is, like, everything that I've seen is, like, building the applications is, like I mean, I don't want to say it's, like, trivial, obviously everything's hard, but what's much harder than building AI applications…”
Altman: AI applications are the best venture investment opportunity in 2025
“Applications are just like the
Obvious place for me, both because of my background, but it's also what I think is like the best place for venture in 20, 25 to be investing because you're basically investing behind the fundamental belief that like AI is going t…”
Ramsaran: Adding standalone healthcare AI applications increases systemic fragmentation
“Everyone is now creating new data systems, creating new AI applications, AI devices, but inherently, if you're adding these in, you're also creating more fragmentation because We now have to use this AI application that only works with this device or only will…”
Deng: AI competition has shifted from model quality to workflow and craft
“Before I would say, 18 months ago, it's like, oh, well, who has the best model? But then coming forward, it's like really who has the best workflow and who has the best product. And we humans are just demanding. We want the best. And so when that, when someone…”
George: AI business models will adopt freemium over simple subscriptions
“And so, you know, I think there's a question of how it will play out. Will it just be a simple subscription or is there gonna be something more You know, freemium that comes along. I would bet on the latter. I would bet on the latter.”
Clark: Evaluating end-to-end AI performance hides upstream system failures
“And what I think a lot of firms are running into right now is if you're only looking at that last step, if you're only looking at the system's performance as a whole, it can be very difficult to understand when, where, and why behaviors are shifting within thi…”
Bornstein: 'AI agent' is just a rebrand for standard AI applications
“I kind of think agent is just a word for AI applications, right? Anything that uses AI kind of can be an agent.”
Abraham: Proving AI applications hallucinate on hard PDFs secures sales calls
“I would upload a hard PDF into AI applications, and I would show them that their application is hallucinating. It would be a very clear, like, here's the document that I sent in, and your model is actually making up information that wasn't there. And for any p…”
Fanelli: AI infrastructure is lagging application demand for the first time
“I think there's this usual, like, VCEO, we should invest in, like, the tools, you know, the picks and shovels instead of the application layer. But I think it's, this is, like, the first time where, like, the infrastructure is lagging the applications.”
Iyer: Accreditation and deployment bottlenecks stall defense AI applications
“Half half the challenge with a lot of the AI applications is you don't have the models accredited. You don't have the models deployed in a way that they can actually be used.”
Husain: AI builders consistently get stuck moving demos to production
“Anytime that I try to help someone build an AI application, they always get stuck on how to move beyond a demo product. And they get stuck like how to systematically improve things and measure it.”
Shankar: Grounded synthetic data generation beats slow human annotation
“People don't know how to do anything other than Plan A, which is to go out and try to collect as much real world data as possible and take months because we're going to employ, like, human annotator teams to do this. Or Plan B, which is I'm going to ask an LLM…”
Klein: AI apps requiring browser interactions need dedicated backend cloud infrastructure
“If you're building applications that rely on a browser and it's more part of a greater like AI app experience, you probably need something that's more like infrastructure, not a consumer app.”
Goyal: Go-to-market strategy for AI applications is identical to traditional SaaS
“There is no difference between taking an AI application to market versus taking the applications to market that used to exist in the past as well.”
Weinberg: Vertical AI founders should evaluate the 'price per token'
“So one thing that I look at is you can look at this by industry and you can look at it by task, which is how expensive is the token? And I, I've come up with like different ways to call this, but basically if you look at something like that share purchase agre…”
Sinofsky: Category-defining AI apps will be entirely novel software concepts
“The apps that ended up mattering on the internet literally didn't exist. Before the internet. And I think that's what people are losing sight of.”
El-Baba: Fast-to-build AI apps without data moats cannot sustain pricing
“Because if it's really quick to build, you're not building a data proprietary moat around what you're building. It's gonna be really hard to sustain the pricing that you see today, and that's gonna become a really, really challenging business proposition.”
El-Baba: AI Winners Will Build Proprietary Datasets from User Workflows
“The next phase and what gets me really excited is there's richness in the data of the users that is being created as they use your product. The more someone puts in an input that's unique as to how they should look at a certain certain asset class or a certain…”
Chip Huyen: AI evaluation metrics must be derived backward from business use cases
“For applications it's really, really important to understand the use cases well, so they can design like the set of metrics and then you can walk backward from that and map it to like the model metrics.”
Haber: AI wedge features will commoditize and model moats are ephemeral
“Is that wedge product alone defensible? I would argue no, right? Today, it feels like magic to the providers that they're working with, but I think that capability is going to become commoditized over time. They may have an advantage because they've trained a …”
Bosworth: Bulk of AI value will accrue to applications, not foundation models
“I think the bulk of the value though, so there will be valuable companies there, but the bulk of the value will be in the application side.”
Taylor: Defining AI companies will be applications, not base models
“The focus on hardware and models and not enough focus on the applications of AI. I think many of the defining companies in AI will be delivering consumer and business solutions that happen to be powered by AI, not just the models themselves.”
Katz: ClickHouse has been used as an AI feature store for years
“And so the reality is ClickHouse has been used for in AI applications or to power AI applications as a feature store for years.”
Palihapitiya: Most AI applications today are toy apps, not production code
“Most of the apps, the overwhelming majority of the apps that we're seeing in AI today are toy apps that are run as proofs of concept and demos and run in a sandbox. It is not production code.”
Chamath: AI apps with 35-40 second response times are dead on arrival
“And the reason is because you could build the best experience in the world that runs on localhost, but if all of a sudden you actually try to launch it as an app and the thing takes 35 and 40 seconds to generate something, it's DOA.”
Hoffman: Few startups are building strong specialized AI apps
“Part of it is, there's such a gold rush with it that relatively few of the companies are doing kind of good apps on this stuff yet, because they're just kind of working on the pure AI general purpose.”
Biswas: AI infrastructure favors mega-incumbents, while AI applications favor startups
“So in that sense, AI infrastructure may be well suited for companies that can invest billions of dollars ahead of time in building big data centers. The applications on the other hand, I think that sort of rapid feedback loop and kind of creativity is really w…”
Casado: Developers ignoring toy-like AI applications will miss the AI wave
“If you don't engage in these kind of things that look like toys, like, this wave will pass you by. That I'm a hundred percent convinced.”
Grimshaw: AI applications will capture massive value and pull through infrastructure
“I think in the arc of time if it is a shift like the internet was in many ways the applications, Which might not look like an applications, right, in the way that we think of them, but might look more like, you know, this control center idea will have profound…”
Grimshaw: Early AI application sign-up spikes resemble 'high fructose corn syrup'
“Like, I think there can be a lot of high fructose corn syrup of adoption. Like, there's an amazing magical moment in a wow, right? When you go experience ChatGPT for the first time, or some of the imagery models for the first time. The rate of adoption of, lik…”
Siroker: Thousands of multi-billion-dollar vertical LLM application companies will emerge
“There's whole categories of companies that are going to be cat, you know, Category defining independent successful big public multi-billion dollar companies that are just applications of large language models in a specific domain for a specific user with a gre…”
Shazeer: The Best AI Applications Have Not Been Invented Yet
“The best applications just haven't even been invented yet that You know, we, you know, we're still at, like invention of electricity kind of moment, or invention of the computer, where we don't really you know, we don't really know what the coolest things are …”
Rauch: A Lot of AI Value Can Accrue at the Last Mile
“And I'm a big believer that that last mile of integration can be where a lot of the value accrues.”
Rauch: Observability is mandatory from v0.1 for AI applications
“It's like letting you provide a great quality of service, but in the AI realm, it's just so mandatory. Like your V 0.1 already needs that critical feedback loop.”