Alcohol

topic on 17 shows · 49 statements across 37 episodes

the Y Combinator Startup Podcast Founder's Journal Startup Acquisition Stories the Pitch We Live to Build American Optimist the Knowledge Project Masters of Scale BigDeal David Senra My First Million the Neon Show WTF is with Nikhil Kamath Top Founders How I Built This TBPN 20VC

49 statements about Alcohol, every show

KNOWLEDGE PROJECT Assertion Supported
Dr. Enders: Alcohol disrupts digestion by irritating immune cells, nerves, and microbiome
“And it's a mixture of alcohol annoying the immune cells, alcohol not being good on the nerve cells, alcohol getting chaos into the microbiome, so all of this comes together and gives you this weird, weird text message on your toilet in the next morning saying,…”
Dr. Giulia Enders Jun 23, 2026 ▶ 37:33 How to Repair and Nourish Your Gut | Dr. Giulia Enders
DAVID SENRA Disclosure
Andreessen: The ideal day is 12 hours caffeine, 4 hours alcohol
“So for a very long time, I always said that the ultimate day, like the perfect day was 12 hours of caffeine followed by four hours of alcohol.”
Marc Andreessen Mar 15, 2026 ▶ 0:12 Marc Andreessen: The World Is More Malleable Than You Think
TBPN Assertion Supported
Saudi Arabia permits alcohol for foreign residents earning over $13,000 monthly
“Saudi Arabia is loosening alcohol rules, letting non-Muslim foreign residents earning over 13,000 dollars you can buy alcohol.”
Jordi Hays Dec 10, 2025 ▶ 28:47 Paramount’s Deal Playbook, Trump Opens Nvidia’s China Door, Saudis Loosen Drinking Laws | Diet TBPN
BIGDEAL Opinion
Lyon: Alcohol Is a Toxin and Risk Factor for Cognitive Impairment
“I do not think alcohol. I think it is a toxin period. And when we were examining people and we were saying, okay, so what is this person's risk factor for some kind of cognitive impairment? Alcohol was on the list.”
Dr. Gabrielle Lyon Oct 9, 2025 ▶ 52:04 Doctor: This Will Strip Your Fat Faster Than Anything! | Dr. Gabrielle Lyon
Arun: Phone addiction is worse than alcohol or smoking
“The worst addiction nowadays, it's not alcohol or it's not smoking. It's not anything else. It is the phone addiction.”
Naveen Arun Oct 9, 2025 ▶ 7:53 Why is lifestyle the next big thing? | Startup Stories Uncut | Episode 1
Negreanu: Mild Alcohol Intoxication Can Act as a Poker Superpower
“Cause with poker, alcohol can lower your inhibition a little bit. So you're gonna just go, trust your instinct. And when I, you know, whenever I've done that, I feel like it's almost like a superpower because It allows you to sort of get past the fear and the …”
Daniel Negreanu Oct 6, 2025 ▶ 48:36 $50M Poker Pro Shares Emotional Intelligence Tricks For Founders
TBPN Insight
Dr. Drew: Alcohol decline aligns with drops in dating and sex
“It fits with the lack of dating and the lack of having sex and the lack of socializing. It, that was the, that was a prime social lubricant for decades.”
Dr. Drew Pinsky Aug 27, 2025 ▶ 24:06 Dr. Drew on Tech, COVID, and Living a Happy Life
20VC Opinion
Galloway: Health risks of alcohol are dwarfed by social isolation for young adults
“And I think the risks to a twenty-five-year-old liver of alcohol are dwarfed by social isolation.”
Scott Galloway Jul 7, 2025 ▶ 26:17 Scott Galloway on Billionaire Happiness, Money & Self-Worth | Why We Should Drink More & Not WFH · 20VC with Harry Stebbings
Y COMBINATOR Assertion Partly supported
Tan: GLP-1 medications reduce compulsive behaviors like nail biting and drinking
“One of the weirder things that's happening with GLP-ONEs, I'm sure you're tracking, is that it gives you unbelievable willpower, like people who bite their nails, They stop biting their nails. Or like, people who struggle with alcohol just because they go on a…”
Garry Tan Jun 27, 2025 ▶ 29:31 Legendary Consumer VC Predicts The Future Of AI Products · Y Combinator
BIGDEAL Assertion Supported
Malik: Chronic Alcohol Use Drives Persistent Male Erectile Issues
“When you look at the data, it's more when people were like chronically having a lot of alcohol use that are really having these problems.”
Dr. Rena Malik Jun 11, 2025 ▶ 55:13 Get Your Sex Life Back! What Everyone Gets Wrong About Sex & Libido: Dr. Rena Malik
BIGDEAL Opinion
Dr. Moore: Today's youth drink far less alcohol than previous generations
“I don't think that today's young people are drinking nearly as much, but when I grew up, everybody was drinking, particularly in places where there was nothing else to do”
Dr. Tyna Moore Mar 26, 2025 ▶ 2:48 Ozempic Expert: They’re Lying To You About Getting Fat | Dr. Tyna Moore
AMERICAN OPTIMIST Assertion Supported
Israetel: Occasional moderate drinking has no statistical impact on human longevity
“If you have a few drinks now and again, it has Literally no statistical impact on longevity or quality of life or anything like that.”
Dr. Mike Israetel Mar 14, 2025 ▶ 8:10 Exercise Scientist: How AI & “Miracle Drugs” Can Make You Superhuman · Joe Lonsdale
AMERICAN OPTIMIST Assertion Supported
Dr. Mike: Nightly drinking beyond three drinks accelerates health downsides exponentially
“If you drink three to four and more drinks most nights, you're going to be paying a small health and longevity downside. And then the negatives exponentially accelerate. After that.”
Dr. Mike Israetel Mar 14, 2025 ▶ 8:31 Exercise Scientist: How AI & “Miracle Drugs” Can Make You Superhuman · Joe Lonsdale
THE PITCH Disclosure
PopCom uses facial recognition to vend regulated items like cannabis and alcohol
“With the customer's permission, we can verify your face against your ID to dispense a product that's regulated. So think Sudafed, think cannabis, think alcohol. That you need an ID to verify. We have that ability.”
Dawn Dixon Mar 3, 2025 ▶ 5:12 Is the ICO Gold Rush Over?
THE PITCH Disclosure
PopCom verifies facial IDs to dispense regulated products like cannabis and alcohol
“With the customer's permission, we can verify your face against your ID to dispense a product that's regulated. So think Sudafed, think cannabis, think alcohol. That you need an ID to verify. We have that ability.”
Dawn Dixon Mar 3, 2025 ▶ 4:42 #31 Are Vending Machines the Future of Retail?
WTF Assertion Partly supported
Chouksey: Alcohol contains DNA-damaging formaldehyde and causes cellular harm
“Alcohol has formaldehyde. Pomaldehyde has the potential to damage your DNA. So at a cellular level, it is damaging.”
Jitendra Chouksey Feb 2, 2025 ▶ 2:12:25 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
MY FIRST MILLION Assertion Contradicted
Parr: Alcohol and opioids are the only drugs with lethal withdrawals
“A lot of people don't talk about this, but with alcohol, but I'm pretty sure there's only two drugs you can die from if you try to do it on your own and you could have withdrawals and die and that's alcohol and opioids.”
Sam Parr Jul 29, 2024 ▶ 5:08 6 Things I Learned From Not Drinking For 1 Year
MASTERS OF SCALE Assertion Supported
Cessario: Social media age restrictions heavily constrain marketing for alcohol brands
“There's all these restrictions against what you can run on social media for alcohol because it's age restricted.”
Mike Cessario Jul 11, 2024 ▶ 23:19 How Liquid Death built a $1.4 BILLION brand around water (founder Mike Cessario) | Masters of Scale
WTF Insight
Khaitan: Alcohol brands cannot force sales through heavy capital and advertising
“Because what I believe in alcohol, you cannot push sales. You have to win sales. Like, as I said, first 10,000 is important. So even sometimes I brew with that idea whether is it the right strategy, but in my last 20 to two decades of my experience, I feel It'…”
Abhishek Khaitan Jul 3, 2024 ▶ 2:28:50 Ep #18 | WTF, Alcohol is a $70B Business in India? | Nikhil Kamath explores Gaps & Opportunities · Nikhil Kamath
KNOWLEDGE PROJECT Assertion Supported
Beshore: Alcohol is one of the biggest testosterone inhibitors in men
“Alcohol is one of, men, especially one of the biggest inhibitors of testosterone.”
Brent Beshore Jun 11, 2024 ▶ 46:18 Brent Beshore: Business Brilliance and Happiness at Home
Davis journals every alcoholic drink weekly to prevent addiction
“That's an area where, you know, I keep a journal of every alcoholic drink I have a week. Because I love alcohol.”
Christopher Davis Mar 5, 2024 ▶ 1:48:57 Chris Davis: Three Generations of Wealth
NEON SHOW Assertion Supported
Garg: Drinking alcohol breaks sleep cycles and impairs physical recovery
“If you drink before sleep, and if you're drinking hard liquor, or if you're drinking beer you're, Your sleep cycles are going to be very erratic, and I think most of it goes because of what is happening inside your stomach. You are very dry, and then you will …”
Ankit Garg Jan 5, 2024 ▶ 33:37 Building a 1000Cr comsumer brand in India | Ankit Garg, Founder, Wakefit
20VC Assertion Supported
Franceschetti: Alcohol is the single most impactful disrupter of sleep
“So the most impactful thing of everything is alcohol. Alcohol is massively, is gonna disrupt your sleep massively.”
Matteo Franceschetti Nov 20, 2023 ▶ 1:32:04 Matteo Franceschetti: The Ultimate Hiring Playbook: Five Questions to Ask Every New Hire | E1084 · 20VC with Harry Stebbings
20VC Assertion Supported
Franceschetti: Consuming alcohol typically reduces sleep quality by 20%
“Usually, you lose probably somewhere around 20% sleep quality with alcohol.”
Matteo Franceschetti Nov 20, 2023 ▶ 1:32:29 Matteo Franceschetti: The Ultimate Hiring Playbook: Five Questions to Ask Every New Hire | E1084 · 20VC with Harry Stebbings
MY FIRST MILLION Assertion Supported
Galloway: People on Ozempic drink 60% less alcohol
“They're finding out people on Ozempic drink 60% less alcohol.”
Scott Galloway Oct 24, 2023 ▶ 25:46 If I Could Start Over Again, This Is What I’d Do To Get Rich - Scott Galloway
KNOWLEDGE PROJECT Assertion Supported
Dr. Lagos: Chronic alcohol consumption consistently lowers heart rate variability
“There is evidence, certainly, that chronic alcohol use chronically lowers HRV.”
Dr. Leah Lagos Sep 19, 2023 ▶ 8:16 Dr. Leah Lagos and Joe Mazzulla: Control Your Heart, Conquer Your Stress
WTF Opinion
Mukesh Bansal: Alcohol Is As Harmful As Smoking
“I believe alcohol is as bad as smoking. It's only a matter of time before, ah, I think science already caught up. There is absolutely no dispute as far as science goes. But the mainstream media and the communication has not caught up. I think it's a matter of …”
Mukesh Bansal Jul 2, 2023 ▶ 23:10 Ep #6 | WTF is Health? ft. Nikhil Kamath, Suniel Shetty, Nithin Kamath and Mukesh Bansal · Nikhil Kamath
KNOWLEDGE PROJECT Assertion Not checkable as stated
Dr. Lembke: Alcohol Is the Only Substance With Clear Addiction Thresholds
“Also, we don't really have good data for how much is too much, except for alcohol, where we have pretty good data for that.”
Dr. Anna Lembke Feb 21, 2023 ▶ 13:09 Dr. Anna Lembke: Between Pleasure and Pain
20VC Disclosure
Ilishayev: Alcohol yields GoPuff's lowest margin percentage but highest dollar margin
“Alcohol is our lowest gross margin percentage category, but our highest gross margin dollar category.”
Rafael Ilishayev Nov 2, 2022 ▶ 7:19 GoPuff CEO Rafael Ilishayev: The Plan to Make GoPuff Profitable by 2024 | 20VC #944 · 20VC with Harry Stebbings
20VC Insight
Ilishayev: Alcohol sales are particularly resistant to economic downturns
“Alcohol is particularly resistant to any effects of an economic downturn.”
Rafael Ilishayev Nov 2, 2022 ▶ 32:47 GoPuff CEO Rafael Ilishayev: The Plan to Make GoPuff Profitable by 2024 | 20VC #944 · 20VC with Harry Stebbings
KNOWLEDGE PROJECT Assertion Supported
Huberman: Alcohol lowers body temperature while disrupting temperature perception
“Alcohol actually lowers your body temperature, but your perception of that lower body temperature is disrupted. So part of the reason you can fall asleep When you drink alcohol is because it lowers your body temperature.”
Dr. Andrew Huberman Mar 22, 2022 ▶ 51:44 Andrew Huberman: The Science of Small Changes
KNOWLEDGE PROJECT Assertion Partly supported
Huberman: About 10% of people experience a dopamine surge from alcohol
“Now about 10% of people have a genetic predisposition to get a big dopamine increase from alcohol.”
Dr. Andrew Huberman Mar 22, 2022 ▶ 54:12 Andrew Huberman: The Science of Small Changes
Walker: Alcohol sedates the brain rather than inducing natural sleep
“What you're doing with alcohol is sedating your brain, and sedation is not sleep.”
Dr. Matt Walker Feb 22, 2022 ▶ 31:57 #131 Matthew Walker: The Power of Sleep
KNOWLEDGE PROJECT Assertion Supported
Walker: Alcohol consumption blocks rapid eye movement sleep
“The third of the four problems with alcohol and sleep is that it will block your rapid eye movement sleep or your dream sleep.”
Dr. Matt Walker Feb 22, 2022 ▶ 33:13 #131 Matthew Walker: The Power of Sleep
KNOWLEDGE PROJECT Assertion Supported
Walker: Evening alcohol consumption cuts nighttime growth hormone by 50%
“In fact, there was a frightening study that demonstrated that a couple of doses of alcohol in the evening, sort of getting you, not really tipsy, but kind of close to that, resulted in a 50% five-zero decrease in growth hormone at night.”
Dr. Matt Walker Feb 22, 2022 ▶ 34:37 #131 Matthew Walker: The Power of Sleep
Kan: Startup failures and setbacks turned drinking into an escape mechanism
“Started my first startup and I continued like drinking and it became, you know, it was also like a crutch. Like it wasn't just Okay. I'm going to like go party. It was like, I feel upset about something, right? Like there's something that's not going my way in…”
Justin Kan Feb 15, 2022 ▶ 5:09 Bonus: "How Twitch Co-founder Justin Kan Got Sober" from Imposters
20VC Disclosure
Whoop Data Shows One Glass of Alcohol Can Improve Sleep for Some
“There are certain individuals who we've seen one glass of alcohol can actually make them sleep better. It tends to get slippery from there, so two to three, three to four, then all of a sudden your sleep really should be disrupted.”
Will Ahmed Jan 5, 2022 ▶ 36:28 20VC: Whoop Founder, Will Ahmed on How CEOs Can Perform at their Highest Level, Why There is Value in Struggle Early On, Why Realism is Overrated in Startups and How To Create a Culture of Delegated Decision-Making
Weisbrot: Asian Founders Turn to Alcohol Because Deals Happen Over Drinks
“I think a lot of times with entrepreneurs, especially in Asia, the reason that they get involved with alcohol in particular is because a lot of business is sealed during a drink.”
Sean Weisbrot Feb 2, 2021 ▶ 10:47 36 Years Sober: Why Addiction Is Still Inside My Brain
20VC Assertion Not checkable as stated
Harry Stebbings stopped drinking alcohol in May 2020
“Two weeks ago, I stopped drinking, and I really wanted the accountability of social, and so I tweeted, and I tweeted, I decided today that alcohol was just not something that I needed in my life anymore, and something I was relying on too much.”
Harry Stebbings Jun 1, 2020 ▶ 0:05 20VC: It's Time To Talk About Drinking; How To Stop, The Impact It Has, How Life Changes Post-Alcohol and The Biggest Misconceptions on Drinking with Ryan Petersen, Founder @ Flexport, Justin Kan, Founder @ Twitch, Matteo Franceschetti, Founder @ Eight
20VC Assertion Not checkable as stated
Justin Kan quit drinking alcohol one year ago
“I quit about just over a year ago. Actually, I just hit a year, maybe a month ago, and I wasn't really drinking as much as I used to, but I was still drinking probably 15 to 20 drinks a week, and I just realized that it wasn't serving me anymore.”
Justin Kan Jun 1, 2020 ▶ 4:54 20VC: It's Time To Talk About Drinking; How To Stop, The Impact It Has, How Life Changes Post-Alcohol and The Biggest Misconceptions on Drinking with Ryan Petersen, Founder @ Flexport, Justin Kan, Founder @ Twitch, Matteo Franceschetti, Founder @ Eight
20VC Assertion Not checkable as stated
Ryan Petersen quit drinking alcohol due to severe next-day anxiety
“And that was it for me. I was like, oh, okay. Why am I doing this to myself? It's not worth it. And ever since then I quit cause I don't want to have that feeling anymore.”
Ryan Petersen Jun 1, 2020 ▶ 8:26 20VC: It's Time To Talk About Drinking; How To Stop, The Impact It Has, How Life Changes Post-Alcohol and The Biggest Misconceptions on Drinking with Ryan Petersen, Founder @ Flexport, Justin Kan, Founder @ Twitch, Matteo Franceschetti, Founder @ Eight
20VC Disclosure
Kan: Alcohol Cravings Diminished Significantly After Two Weeks of Sobriety
“After the first couple weeks, it became pretty automatic, and I wasn't craving it as much anymore.”
Justin Kan Jun 1, 2020 ▶ 18:47 20VC: It's Time To Talk About Drinking; How To Stop, The Impact It Has, How Life Changes Post-Alcohol and The Biggest Misconceptions on Drinking with Ryan Petersen, Founder @ Flexport, Justin Kan, Founder @ Twitch, Matteo Franceschetti, Founder @ Eight
20VC Opinion
Schlafman: Alcohol is effectively ethanol and a cellular poison
“Well, yeah, I mean, I think the biggest misconception is that alcohol is, not that it's healthy, obviously there are real severe health effects, but because it's a legal substance, I don't think people recognize that you're effectively ingesting a poison, righ…”
Steve Schlafman Jun 1, 2020 ▶ 21:58 20VC: It's Time To Talk About Drinking; How To Stop, The Impact It Has, How Life Changes Post-Alcohol and The Biggest Misconceptions on Drinking with Ryan Petersen, Founder @ Flexport, Justin Kan, Founder @ Twitch, Matteo Franceschetti, Founder @ Eight
HOW I BUILT THIS Assertion Supported
Deadly Pathogens Cannot Grow in Beer
“Well, I guess one of the things about beer making is that things like that don't grow in beer. [584] Guy Raz: I gotcha. [585] Guy Raz: Okay, fine. [586] Guy Raz: Good to know. [586] Ken Grossman: The alcohol, the pH, and the hops are all inhibitory to [591]…”
Ken Grossman Mar 30, 2020 ▶ 9:38 Sierra Nevada Brewing Company: Ken Grossman
Latimore: Total alcohol abstinence is easier than attempting moderation
“I'm really bad at moderation. I'm just bad at it. That's why I don't drink, right? It's easier for me to not drink than it is to figure out which ones, what's enough and what's not enough, right?”
Ed Latimore Aug 9, 2017 ▶ 27:53 #21 Ed Latimore: The Warrior Poet
Latimore: Alcohol caused or exacerbated 95% of his personal problems
“I used to say, 95% of my problems, my personal problems are exacerbated, are caused by the influence of alcohol.”
Ed Latimore Aug 9, 2017 ▶ 33:39 #21 Ed Latimore: The Warrior Poet
Latimore: Quitting Alcohol Completely Un-Mutes Emotional Sensitivity
“I say that you, it's like taking sunglasses off and seeing the light. Your eyes hurt because they're getting used to the light and the sunglasses analogy would like your emotions. None of my emotions are muted. I feel things completely.”
Ed Latimore Aug 9, 2017 ▶ 35:48 #21 Ed Latimore: The Warrior Poet
Naval Ravikant uses daily morning workouts to checkpoint alcohol's negative physical effects.
“When you're working out every day, you can checkpoint yourself very easily, like, oh, well, this exact thing that I do every single morning is suddenly harder, so therefore I'm weakened from the alcohol from last night. So the morning workout checkpoint really…”
Naval Ravikant Apr 11, 2017 ▶ 24:28 #18 Naval Ravikant: The Angel Philosopher
Callahan: Coffee and alcohol are two recession-proof businesses
“Coffee, alcohol, man. Those are the two recession proof businesses.”
McCabe Callahan Apr 1, 2017 ▶ 6:50 EP 616: His Coffee Shops Do $1.8M But His Crowdfunding Platform is More Impressive With $550k 2016 Revenue on 486 Projects With $2.5M Funded with CEO McCabe Callahan

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