Python

product on 36 shows · 103 statements across 92 episodes · said 1,083 times in 497 episodes since 2013

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2014 13 mentions in 7 episodes 2 per episode
2013 17 mentions in 7 episodes 2 per episode

every mention on every show, scene by scene, with the transcript →

The latest 60 statements about Python, every show

Dean: Code translation is an ideal AI use case due to existing tests
“A use of a coding agent that works extremely well, is you can ask today's models to translate software from one computer language to another very effectively, because in that case, you actually have a incredibly detailed specification. You have the whole softw…”
Jeff Dean Jul 30, 2026 ▶ 32:59 Jeff Dean: The 1% Rule for Building in AI · Y Combinator
20VC Insight
AI Agents Parse Messy Files Best Via Throwaway Python Generation
“What we found works amazingly is literally to give the files to an agent, tell it to write Python to get these files into a standardized format, because they're not very good at parsing files, but they're incredibly good at code gen, and so you can tell it to …”
Fred Turner Jul 18, 2026 ▶ 44:24 We Built Our Own Salesforce in Months. Here's Why We're Cancelling the $600K Contract | Curative CEO
20VC Insight
AI Creates Better CAD Models Via Python Than Direct 3D Vectors
“You can generate really good CAD models by having it write Python to make the CAD model. Like, it's not good at, necessarily good at, like, three-D space visualization or outputting a drawing Right, as vectors, but it's really, really good at generating plausi…”
Fred Turner Jul 18, 2026 ▶ 1:21:15 We Built Our Own Salesforce in Months. Here's Why We're Cancelling the $600K Contract | Curative CEO
Bubna: AI Agent Developers Prefer TypeScript Over Python
“And the interesting thing with, like, the agent stuff is people use their TypeScript SDK a lot more because they're not actually doing anything that needs ML.”
Akshat Bubna Jul 8, 2026 ▶ 56:19 The Future of AI Infra: from Kubernetes to Agent Sandboxes — Akshat Bubna, Modal CTO
BIG TECHNOLOGY Assertion Not checkable as stated
Krieger: Anthropic dynamic workflows autonomously converted hundreds of thousands of lines of code
“We have a feature called dynamic workflows where you can have it like also break down the task into like a lot of subtasks. And I trusted it to sort of not just do the individual action, but here's like a whole language conversion of millions of hundreds of th…”
Mike Krieger Jun 26, 2026 ▶ 2:32:00 Big Technology AI Summit (full): Greg Brockman, Mike Krieger, Aaron Levie & Friends of The Podcast
BIG TECHNOLOGY Assertion Not checkable as stated
Krieger: Fable autonomously converted hundreds of thousands of Python lines to TypeScript.
“And I trusted it to sort of not just do the individual action, but here's like a whole language conversion of millions of hundreds of thousands of lines of code at that point. Go off and do it, go plan it, go execute it, go verify the work, double verify the w…”
Mike Krieger Jun 25, 2026 ▶ 11:41 Anthropic's Labs Lead On Fable's Capabilities + Building AI-Native Products — With Mike Krieger
Fredrikson: Formal software verification takes 10 to 20 times longer than Python
“The reason people don't do it is that it's not easy and it's not fun, right? It takes you like 10 or 20 times as long to like fight with the type checker, which is essentially like proving that you don't have a vulnerability as if, as it would if you just like…”
Matt Fredrikson Jun 22, 2026 ▶ 43:10 AI Security After Codex and Claude Code — Zico Kolter & Matt Fredrikson, Gray Swan
Hong: Lean and Rust yield superior reinforcement learning convergence over Python
“If you want proof to be informal math, It's very annoying, because then that's, like, just makes objective function. Your code is something like Python, your proof is, say, natural language, math proof. You will not have very strong RL kind of performance, rig…”
Carina Hong Jun 3, 2026 ▶ 30:00 Scaling Past Informal AI - Carina Hong, Axiom Math
LATENT SPACE Assertion Supported
Swyx: TypeScript overtook Python in the annual GitHub developer survey
“I think this year is the year that TypeScript overtook Python in the GitHub survey, and I didn't really foresee that coming.”
Shawn Wang May 7, 2026 ▶ 15:13 Senior Dev: This "Grill Me" Prompt Is Going Viral Among Top Engineers
MAD Assertion Not checkable as stated
A complete modern LLM takes only 200 to 300 lines of Python
“You have this code this code to build a complete large language model that can train on a large data set and learn to speak, runs on GPUs yes, eventually is trained with RL and tool calls. That entire set of code, probably two to 300 lines of Python code.”
Zico Kolter May 7, 2026 ▶ 1:13:46 OpenAI Board Member Zico Kolter: Modern AI Is Just 200 Lines of Code
Singleton: TypeScript is the optimal language for AI-driven development
“TypeScript is an amazing language for AI because there's tons of training data. In the models and it's strongly typed. And actually at the company, we built most of the stack in TypeScript, and we have this amazing property, which is we have type safety all th…”
David Singleton Mar 20, 2026 ▶ 43:12 Dreamer: the Agent OS for Everyone — David Singleton
NO PRIORS Insight
Karpathy: Core LLM training algorithm requires only 200 lines of Python
“Training neural nets and LLMs specifically is a huge amount of code, but all of that code is actually complexity from efficiency. It's just because you need it to go fast. If you don't need it to go fast and you just care about the algorithm, then that algorit…”
Andrej Karpathy Mar 20, 2026 ▶ 1:01:57 Skill Issue: Andrej Karpathy on Code Agents, AutoResearch, and the Loopy Era of AI
TBPN Insight
Cuban: Students Mastering AI Agents Can Capture Small Business Consulting Demand
“I think particularly for small, medium-sized businesses and some large businesses, they're not gonna have that skill set. It's not gonna be natural for them to do that, and I think kids coming out of school today that have taken some Python, don't have to be c…”
Mark Cuban Mar 19, 2026 ▶ 16:27 FULL INTERVIEW: Mark Cuban on Robots, AI, Self-Driving, and Advice to Students
Rieseberg: Users will not scrutinize AI-generated scripts in daily workflows
“Because I kind of believe that Once it starts becoming a part of your workflow, you're probably not either, either you don't have the skill to understand whether or not this Python script is safe, or you're not going to read it anyway.”
Felix Rieseberg Mar 17, 2026 ▶ 1:11:04 Anthropic’s Felix Rieseberg on AI Coworkers, Local-First Agents, and the Future of Knowledge Work
LATENT SPACE Assertion Supported
Colvin: Monty executes Python in single-digit microseconds
“I mean, in a hot loop, we can run, we can go from code to execution result in under a microsecond in like 800 nanoseconds. In reality, it's like single digit microseconds to run code or single digit microseconds to run the next step of a REPL or single digit m…”
Samuel Colvin Mar 14, 2026 ▶ 5:13 ⚡️Monty: the ultrafast Python interpreter by Agents for Agents — Samuel Colvin, Pydantic
Colvin: LLMs are 100x faster under four specific engineering conditions
“My take is that there are four, four things where if you can cover all four of these things, LLMs are not like three X faster or five X faster. They're like a hundred X faster.”
Samuel Colvin Mar 14, 2026 ▶ 11:41 ⚡️Monty: the ultrafast Python interpreter by Agents for Agents — Samuel Colvin, Pydantic
CHEEKY PINT Assertion Not checkable as stated
Pope: AI labs apply RL to software code, not chip architecture
“Models are extremely good at Rust and Python. They've done a lot of RL on them. They have not done as much RL on Verilog. They've done almost none on, okay, write, write me a markdown file that describes a chip architecture.”
Reiner Pope Feb 26, 2026 ▶ 45:39 Reiner Pope of MatX on accelerating AI with transformer-optimized chips
O'Laughlin: Claude for Excel is much worse than Claude Code with Python
“Cloud for Excel is much worse than cloud code using Python to use the Excel skills to then deposit into.”
Doug O'Laughlin Feb 24, 2026 ▶ 31:18 Claude Code for Finance + The Global Memory Shortage: Doug O'Laughlin, SemiAnalysis
Y COMBINATOR Assertion Not checkable as stated
French-Owen: OpenAI Codex performs particularly well on Python monorepos
“Codex works very well on Python mono repos.”
Calvin French-Owen Feb 6, 2026 ▶ 42:46 We're All Addicted To Claude Code · Y Combinator
20VC Assertion Not checkable as stated
Fuse Energy hires backend developers with zero Python experience
“So although our whole backend is in Python we will hire any backend developer even if they know nothing about Python.”
Alan Chang Jan 5, 2026 ▶ 33:50 Fuse CEO Alan Chang: The Revolut Playbook of Speed & Ownership, Why Founders Aren’t Ambitious Enough · 20VC with Harry Stebbings
MAD Assertion Supported
Kaiser: GPT-V Pro solves dot puzzles by running Python code loops
“The GPT-V Pro will run Python code to extract these dots from an image, and then it will count them in a loop.”
Łukasz Kaiser Nov 26, 2025 ▶ 50:08 What’s Next for AI? OpenAI’s Łukasz Kaiser (Transformer Co-Author)
NO PRIORS Insight
Ramaswamy: AI agents should use specialized tools over maximalist LLMs
“A smarter person is going to say, no, they should not do math. Instead, I should write the two lines of Python, which I know how to, you know, direct and run the Python in order to solve the math problem. I think of trust in a very similar way. There are well-…”
Sridhar Ramaswamy Nov 6, 2025 ▶ 40:13 No Priors Ep. 139 | With Snowflake CEO Sridhar Ramaswamy
LATENT SPACE Disclosure
Vercel shipped zero-config deployment for Flask and FastAPI
“What we have done over the last weeks is we have shipped like zero config support on Vercel for all the popular Python framework like Flask and FastAPI.”
Malte Ubl Nov 1, 2025 ▶ 32:31 ⚡️ Ship AI recap: Agents, Workflows, and Python — w/ Vercel CTO Malte Ubl
Y COMBINATOR Disclosure
Heller: Casetext built CoCounsel with plain Python, dismissing frameworks like LangChain
“And to be honest, a lot of the stuff that we built while building co-council was exactly like this. Every time you do this task, you're basically gonna take the same six or seven steps. And you don't need to have, frankly, like fucking Langchain or whatever. J…”
Jake Heller Oct 28, 2025 ▶ 14:16 From Idea to $650M Exit: Lessons in Building AI Startups · Y Combinator
BIG TECHNOLOGY Assertion Supported
AI remains weak at calculations without executing code in virtual machines
“And you know, more importantly right now, AI, we're in a world where, where AI is not good at calculating things yet. So generally you're having to spin up a virtual machine and run Python or something on there. To actually perform those spreadsheet calculatio…”
Zeb Evans Oct 10, 2025 ▶ 6:25 How Business Software Transforms In The Age Of AI — With Zeb Evans
MIXERGY Insight
Howard: Modern AI removes the 10x earning advantage of software coders
“Until 2023, Being really good at coding, whether that was JavaScript, Python, PHP, or anything else, meant you had essentially 10 X or more the earning potential and the ability to build quality solutions than everybody else in the world. And that has been the…”
Rob Howard Sep 10, 2025 ▶ 16:09 #2279 How are there so many AI agencies?
BIG TECHNOLOGY Assertion Not checkable as stated
Masad: AI coding is less impactful for Rust, C, and Go than JavaScript and Python
“It is not as impactful right now on writing Rust code or C or go whatever as it is on JavaScript and Python and higher level languages.”
Amjad Masad Aug 11, 2025 ▶ 51:54 Vibe Coding: Everything You Need To Know — With Amjad Masad
Taylor: Python is a comically bad programming language for AI to generate
“Python is probably the most common generated code just because how much it's in the training data and data scientists love Python and I love Python too. It's such a comically bad thing for AI to generate just because it's one of the most inefficient programmin…”
Bret Taylor Jul 31, 2025 ▶ 39:32 He saved OpenAI, invented the “Like” button, and built Google Maps: Bret Taylor (Sierra)
BI tools overfocus on technical users; most people shouldn't learn SQL
“The sort of business intelligence applications is they really focus on technical users. So if you could write SQL or Python, you could do whatever you want in them to give them a really powerful interface, but the vast majority of people, they're not going to …”
Rob Woollen Jun 30, 2025 ▶ 14:29 He went 7 years with no revenue— then grew to $100M ARR. | Rob Woollen, Co-Founder of Sigma · PMF Show
LATENT SPACE Assertion Supported
Lloyd: Warp translates natural language in any REPL session
“So if you're doing like work in Node or Python, Postgres, MySQL, it works in any REPL and it's a it's a pretty differentiated and cool feature of Warp.”
Zach Lloyd Jun 25, 2025 ▶ 21:22 ⚡️Warp 2.0: the Agentic Development Environment - Zach Lloyd and Ben Holmes
LENNY'S PODCAST Prediction Not checkable as stated
Deng: Future generations will not need to write code for work
“I don't actually think he's gonna have to code when he grows up. I think that's gonna be a solved problem, but it's a very, very valuable skill because I think learning to program is learning how to think structure in a structured way, right?”
Peter Deng Jun 22, 2025 ▶ 12:55 From ChatGPT to Instagram to Uber: The quiet architect behind the world’s most popular products
LENNY'S PODCAST Assertion Not checkable as stated
Deng: ChatGPT often just writes and executes Python code internally
“When ChatGPT does something really interesting, I tell people it's oftentimes just writing Python code and interpreting it.”
Peter Deng Jun 22, 2025 ▶ 20:21 From ChatGPT to Instagram to Uber: The quiet architect behind the world’s most popular products
LATENT SPACE Assertion Not checkable as stated
Lattner says Mojo is 10,000x faster than Python and beats Rust
“Mojo is not just a little faster than Python, it's faster than Rust. So it's like tens of thousands of times faster than Python, and it's in the Python family.”
Chris Lattner Jun 13, 2025 ▶ 15:29 The Shape of Compute (Chris Lattner of Modular)
LATENT SPACE Prediction Not checkable as stated
Kirkos: Traditional spreadsheet formulas will lose ground to Python
“I think formulas will be used less in favor of Python.”
David Kirkos Jun 10, 2025 ▶ 25:57 Quadratic: The AI Spreadsheet
MAD Assertion Supported
Howard: FastHTML enables rich web applications in a single Python file
“So we created this thing called fast HTML, which brings all these ideas together. And lets you create arbitrarily rich, sophisticated web applications in a single Python file.”
Jeremy Howard May 15, 2025 ▶ 47:41 Jeremy Howard on Building 5,000 AI Products with 14 People (Answer AI Deep-Dive)
TBPN Insight
Brown: OpenAI's o3 already achieves practical program synthesis
“Like when people say program synthesis, like we're already there, like O three is program synthesis, but the programs are like JSON and Python.”
Will Brown Apr 26, 2025 ▶ 9:37 Why Humor Is the True Test of AI Intelligence | Will Brown on TBPN
NO PRIORS Disclosure
Fulford: Deep Research Uses a Text Browser and Python Execution Tool
“So right now we just have the browsing tool, which is a text based browser, but it can see embedded images and like open PDFs. And then also it has access to a Python tool so it can do analysis and calculations and plot graphs and things like that.”
Isa Fulford Apr 24, 2025 ▶ 6:28 No Priors Ep. 112 | With OpenAI Deep Research, Isa Fulford
Mlejnsky remains bullish on JavaScript and web developers driving AI adoption
“I still remain very bullish web developers and JavaScript world, TypeScript world, even though we have, like, a ton of usage from Python but there's so many web developers, and it's easier and easier to use LLMs. I really think that you need to cater to these …”
Vasek Mlejnsky Apr 24, 2025 ▶ 19:16 Why Every Agent needs Open Source Cloud Sandboxes
LATENT SPACE Assertion Not publicly verifiable
Mlejnsky: E2B sees 250k JavaScript and ~500k Python SDK monthly downloads
“From number of downloads of our SDK per month, it's like, 250,000 JavaScript, close to around half a million Python.”
Vasek Mlejnsky Apr 24, 2025 ▶ 20:16 Why Every Agent needs Open Source Cloud Sandboxes
Shah: The AI industry does not need a new language to replace Python
“He was talking about like, oh, we need a different language than Python or whatever that is like built for built for AI and built. It's like, No, Brett, I don't think we do actually. It's just fine. It deals with just fine, just expressive enough. And it's nic…”
Dharmesh Shah Mar 28, 2025 ▶ 50:27 The Agent Network — Dharmesh Shah, Agent.ai + CTO of HubSpot
LATENT SPACE Disclosure
Snipd builds on Python, GCP, and Flutter for cross-platform clients
“So the general tech stack is our entire back end is, or 90% of our back end is written in Python. Hosting everything on Google Cloud platform, and our front end is written with, well, we're using the Flutter framework.”
Kevin Ben-Smith Mar 14, 2025 ▶ 28:39 Snipd: The AI Podcast App for Learning — with CEO Kevin Ben-Smith
NO PRIORS Insight
Dohmke: Programming languages remain the essential deterministic layer below AI prompts
“We have the machine language layer, you know, which is Python or Ruby or Rust, right? Those are effectively abstractions of the chipset and the machine instruction set. And that's the last layer that's deterministic, right? Like programming language inherently…”
Thomas Dohmke Mar 13, 2025 ▶ 17:17 No Priors Ep 106 | With GitHub CEO Thomas Dohmke
NO PRIORS Prediction Not checkable as stated
Dohmke: Future programming languages will be closer to human natural language
“I think there's going to be a next programming language after Python and TypeScript and Rust and Rust in itself, you know wasn't really a thing five years ago. And then, so there's going to be more languages that are probably closer to human language and to be…”
Thomas Dohmke Mar 13, 2025 ▶ 42:45 No Priors Ep 106 | With GitHub CEO Thomas Dohmke
LATENT SPACE Prediction Not checkable as stated
The Fundamental Language of AI Will Likely Remain Python
“The things that language models understand best tend to be the kind of piece of code that are represented on the internet. You know, maybe I don't think a lot of people would be happy with this, that maybe the kind of fundamental language of AI becomes Python …”
Misha Laskin Mar 7, 2025 ▶ 12:53 Solve coding, solve AGI [Reflection.ai launch w/ CEO Misha Laskin]
20VC Insight
Bonaci: AI Eliminated the Need for Growth Candidates to Be Technical
“You don't need to be nearly as technical as you used to like, AI can help you write the code. It can tell you other ways of doing things. Like it's even just like in that element of like who I would used to like have a bias for hiring. It's totally changed.”
George Bonaci Feb 28, 2025 ▶ 43:42 George Bonaci, VP of Growth @Ramp: How Ramp Became the Fastest Growing SaaS Company Ever |E1264 · 20VC with Harry Stebbings
Bret Taylor Mocks Using AI to Write Unsafe, Slow Python Code
“I think that we're bringing the cost of writing code down to zero. So the fact that we're still writing Python with AI cracks me up just cause it's like literally was designed to be ergonomic to write, not, not safe to run or fast to run.”
Bret Taylor Feb 11, 2025 ▶ 38:49 The AI Architect: Bret Taylor
Colvin: Pydantic and FastAPI normalized Python type-hint schemas
“Back in 2017, when I first started it, the like different thing it was doing was using type int to define your schema. That was controversial at the time. It was like genuinely disapproved of by some people. I think the success of Pydantic and libraries like f…”
Samuel Colvin Feb 6, 2025 ▶ 1:36 Agent Engineering with Pydantic + Graphs — with Samuel Colvin, CEO of Pydantic Logfire
LATENT SPACE Prediction Open · timeframe Feb 2028
Colvin: Rust-native data storage could yield 3x to 5x Pydantic speedup
“We have plans to move some of the, basically store the data in rust types after validation. Not convert to Python types. So then if you were doing like validation and then serialization, you would never have to go via a Python type. We reckon that can give us …”
Samuel Colvin Feb 6, 2025 ▶ 3:50 Agent Engineering with Pydantic + Graphs — with Samuel Colvin, CEO of Pydantic Logfire
Comfyanonymous: PyTorch Lacks Fine-Grained Memory Control for Complex Pipelines
“The problem with PyTorch is it's high levels. Don't have that much fine-grained control over, like specific memory stuff, so kind of have to leave, like, the memory freeing to Python and PyTorch, which is, can be annoying sometimes.”
comfyanonymous (Comfy) Jan 4, 2025 ▶ 33:13 AI Engineering for Art - with comfyanonymous
Moura: Agent behavior is tuned in YAML, while precision is enforced in Python
“A lot of like the optimization, like what happens, especially on the fuzziness parts, like on the actual agents is on these agents and tasks. I got a YAML files. It's where I can, like, you're going to be like spending a lot of time, like to make sure that you…”
João Moura Dec 28, 2024 ▶ 1:37:56 How To Create Ai Agents From Scratch (CrewAI, Zapier, Cursor)
Neubig: Arbitrary Python Execution Beats Individual Agent Tool Calls
“And the method that we adopt in open hands instead is we provide these tools, but we provide them by just giving a coding agent the ability to call arbitrary Python code. And in the arbitrary Python code, it can call these tools. We expose these tools as APIs …”
Graham Neubig Dec 25, 2024 ▶ 8:21 Best of 2024 in Agents (from #1 on SWE-Bench Full, Prof. Graham Neubig of OpenHands/AllHands)
TBPN Insight
Coogan: LLMs let software engineers use Python for lower-level robotics languages
“I do think, though, there should be more like, intellectual flexibility between the disciplines, especially with, like just how easy LLMs translating between different languages will be, so it's like, oh, yeah, there's some sort of, like, Little bit trickier, …”
John Coogan Nov 3, 2024 ▶ 1:10:28 The Secret Billionaire Party (ep6)
MAD Disclosure
Bernhardsson: Modal containerizes Python code to scale execution to thousands of GPUs
“Modal makes it easy to build, scale and deploy applications in the data, AI, machine learning realm. So, so we basically, you can think of as like, we take, you write a little bit of Python code, and we take that code, we stick it in a container, we execute th…”
Erik Bernhardsson Oct 31, 2024 ▶ 1:51 Can AI Infrastructure Work Like Magic? Erik Bernhardsson, CEO, Modal
Goyal: Python Dominates AI but TypeScript Dominates Product Building
“At the time, and still, like, AI is sort of at least nominally dominated by Python, but product building is dominated by TypeScript.”
Ankur Goyal Oct 11, 2024 ▶ 1:02:51 Production AI Engineering starts with Evals
PRODUCT MARKET FIT Assertion Supported
Lorenc: Standard Docker Hub Python images carry 1,400 vulnerabilities
“Like the Python image, the most up-to-date Python image, if you're going to start writing Python code, and you grab that from like Docker Hub or something like that, it'll have 1400 vulnerabilities before you even start writing your code.”
Dan Lorenc Oct 11, 2024 ▶ 17:30 He quit Google with no startup idea, raised $50M from Sequoia with no revenue— & grew to 8 figure... · PMF Show
NO PRIORS Disclosure
Goyal: Vast majority of Braintrust customers now use TypeScript over Python
“First of all a vast majority of our customers use TypeScript and, you know, early on, some of our customers were dealing with, like, should we use TypeScript or Python? And some teams were using TypeScript, some teams were using Python. Now, almost everyone, i…”
Ankur Goyal Oct 8, 2024 ▶ 23:43 No Priors Ep. 85 | CEO of Braintrust Ankur Goyal
NO PRIORS Opinion
Goyal: TypeScript's type system makes it better suited for AI than Python
“Another thing is that TypeScript as a language is inherently better suited for AI workloads because of the type system. So the type system basically allows you to launder, you know, the crazy stuff that comes out of an AI model into a well-defined structure th…”
Ankur Goyal Oct 8, 2024 ▶ 24:25 No Priors Ep. 85 | CEO of Braintrust Ankur Goyal
Karpathy: Python and PyTorch are crutches for finite human intelligence
“The use of Python and PyTorch and everything else is just a crutch, because we humans are finite. We have finite knowledge, intelligence, and attention.”
Andrej Karpathy Sep 21, 2024 ▶ 22:17 llm.c's Origin and the Future of LLM Compilers - Andrej Karpathy at CUDA MODE
CAPITAL ALLOCATORS Assertion Not checkable as stated
Python has largely replaced Excel in institutional finance, says Auby
“Python has certainly taken over everything that we do on the finance side, even at Texas teachers. I mean, kids show up and it's not necessarily just Excel anymore. It's Python programming.”
Jace Auby Sep 9, 2024 ▶ 12:38 Jase Auby - Risk, Size, and Talent at Texas Teachers (EP.404)
Brown: Building apps in Python with AI is easier than Next.js
“And if we just use, like, Python and we didn't care about how good it looks, it would be much easier to create. Because Python is very straightforward and AI is very good at creating it.”
Riley Brown Sep 1, 2024 ▶ 53:34 I can't believe we coded an app with AI in 67 mins (V0, Cursor AI, Replit, Claude AI)

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