The Ledger, every show

“Yeah, I think the four, four big. And so it's like, okay, so go to Gerber's website, I can't find heavy metals results anywhere. And then I realized my VPN's on, and I'm coming from a server outside of California, they've IP blocked.”

“I'm fundamentally proposing that the human race is no longer qualified to manage our affairs.”

“When people feel suicidal, I am deeply empathetic. It is rational to want to kill oneself. It's reasonable.”

“When we test organic, It typically performs worse than non-organic on many, many variables.”

“Our primary hypothesis is as this evolves, the major shift is humans are going to want life. Like, you know, if AI takes our jobs and they take what we do and we want to find new identity, there's going to be a major shift towards don't die. And it's going to …”

“I think that we will exceed them in value in many core areas. Because they, you, they can take, you know, well-structured, well-funded clinical trials. But then other things like peptides that are very promising. They're not going to have the clinical work.”

“Ok, my prediction for twenty-twenty-six is it will be the year that YOLO dies. We will begin transforming ourselves from a you only live once to don't die.”

“And if we're honest, the majority of you in this room have some moderate to serious mental health problem.”

“Don't die is the next major ideology on par with democracy, capitalism, Christianity, Islam.”

“We looked at diapers. There was a dangerously high level of glyphosate in diapers.”

“So the cost of their goods to source their actual ingredients is less than 10 dollars, probably seven dollars. They sell it for one time, 99 dollars and subscription for 79. They pay influencers 20% of that. So every time a health influencer plugs AG one, they…”

“Most of it. Really? Yeah, most of it, yeah.”

“I can't imagine a situation where we humans are still the architects of intelligence in some duration of time.”

“If death is not inevitable, Then you have to reconsider all of your existential scaffolding.”

“The meaning of life to me is, is like, is this, that when intelligence reaches a certain level of capability, which is right now, like after 4.5 billion years on this earth, In the past few years, we have reached a critical point after 4.5 billion years for th…”

“I really don't want to die. And I'm here on this planet. With a bunch of people who do.”

“Right now we're bringing super intelligence into the world and we're doing it in the games we play now, which is go to war. Become more effective at killing people. Acquire more wealth. Like, we're playing games of violence and death, and if we do that, we're …”

“These systems are going to run faster than our minds, the more efficient than our minds, they'll have more data than our minds, so the future is us in this autonomous network Of computational goal alignment among all intelligence. Now, that sounds unfathomable…”

“When I gave my father plasma, my father's speed of aging slowed by the equivalent of 25 years. So from a 71 year old to a 46 year old, and those results remained the stable for six months, which is the last measurement we did.”

“What we found in psilocybin though, is it had, we found a first in human observation. It had this metabolic reset in the brain where my blood glucose before this was in the top. 99.5 percentile of all the population. Okay. After it went to the top 99.9 percent…”

“Five MEO DMT compared to psilocybin, like just absolutely like blasted clean. My default mode network. It felt like psilocybin dampens it, like it softens it, but this thing just annihilated my default mode network.”

“If I just subjectively compare my experience with five MEO to having a better diet and exercising every day and sleeping well and doing the sauna and doing hyperbolic oxygen therapy, this was more efficacious than all of them. In terms of the reset of me as a …”

“One investor told me that he even put it in the deal docs that, you know, if we invest, you're not going to do these psychedelics because they wanted to minimize the risk profile.”

“We have the organoids stood up. We haven't done our first takes yet.”

“I felt like it was like 30, 40 years of Psychological rejuvenation. Like, you know, it's like to transform me back to a childlike state. That is insane. I don't get that from the sauna. Or from eating well. Or from sleeping well.”

“So it's called Immortals. A million dollars a year. And it's my exact protocol. So my doctors, my concierge team, all the testing infrastructure.”

“We are giving birth to some kind of super intelligence. We don't know what it is. We don't know what kind of scale, but it's big. It's important.”

“What a lot of people don't realize is this endeavor is entirely about AI alignment.”

“It's probably the most successful anti-aging drug ever built.”

“Basically, somebody's gonna set up shop in longevity and ride a multi-trillion dollar ride. So that's what we're trying to do, is we're trying to just be home base, win the early innings of longevity, and then ride for the multi-trillion dollar market.”

“It's very unlikely. They've done such a great job executing. I sold Braintree in 2013, so they've been building 12 years since. They've done such a good job making that airtight.”

“Basically, I have the best biomarkers of anybody in the world.”

“So you guys, the single best thing I've learned out of everything I've ever done is your resting heart rate before sleep is the best thing you can do for your health.”

“So the key marker is lowering your resting heart rate before bed. That is the number, I'd say if you could mark, if you could optimize one marker in your entire life, it's that.”

“I did eight months of perfect sleep. A hundred percent sleep every night to show I could do high quality sleep.”

“Yeah, you know, I did it because my dad was experiencing cognitive decline, and he called me in a panic, and he said, I will do anything to save my consciousness, and so I did it for him.”

“So actually next week there's going to be, do you know Polymarket? Yeah. They're launching a market on my nighttime erections.”

“I don't know of many high functioning people who routinely use marijuana, maybe occasionally for enjoyment, but very few like actual regular practitioners.”

“I think there's only one thing going on. We're giving birth to super intelligence. Nothing else matters besides that. We're giving birth to a form of intelligence that's going to change our existence unfathomably, and in timeframes which are hard for us to und…”

“By 20, 27, the same time when we think that These AI agents will be as good as our best AI researchers, that there's a billion of us around the world that are practicing, don't die, economically, politically, religiously, morally, socially, ethically, all the …”

“I wouldn't take anything unless you can measure it.”

“I mean, it's the side effect profile. It's the, it messes with lipids. It messes with blood glucose. I had small tissue infection soft tissue infections. It raised my resting heart rate. And so we knew we had these side effects, but we just wondered, like, whe…”

“And specifically I think that AI may produce in the next five years, you know, decades, if not a century worth of progress.”

“My cardiovascular capacity is in the top 1.5% of 18 year olds.”

“When I eat my last meal of the day, I have all my digestion finished. So when I go to bed, my resting heart rate is around 46 beats per minute. And if it's a 46, I'm going to have a perfect night's sleep. If I eat at five PM or six PM, then my resting heart ra…”

“I think they say, you're In the eve before the creation of super intelligence, and the intelligence you're creating is growing at a speed faster than you can comprehend. That renders your ability to predict the future to zero.”

“The only objective is that intelligence continues to thrive in this part of the galaxy, but your games of martyrdom are basically a death cult, and you normalize to it, and you can't see it.”

“The headline with Blueprint is that it's two million dollars a year. It's not. It's, you know, like, 1500 dollars a month, which includes your groceries.”