PBMs

topic on 9 shows · 14 statements across 11 episodes

Acquired Another Podcast Cheeky Pint American Optimist A Product Market Fit Show the a16z Podcast All-In TBPN 20VC

14 statements about PBMs, every show

Loiacono: Breaking Out PBM Revenue Streams by Client Is Almost Impossible
“My competitors had to suddenly contemplate, am I going to disclose what I'm making on spread pricing? Acquisition costs, three 40 B rebates, performance management fees, you know, like price protection. They have all these revenue streams and to break it out b…”
AJ Loiacono Aug 24, 2026 ▶ 32:51 He spent $0 on marketing—raised $400M at $3.25B valuation | Judi Health
TBPN Opinion
Cuban: Lilly and Novo Bypassing PBMs for GLP-1 Drugs Is Brilliant
“No, cause that stuff's going to come down in price and now, you know, Lilly and Novo are smart now with their GLP ones. They're working around the PBMs and doing direct-to-patient, direct-to-company, and that was brilliant. That was really smart.”
Mark Cuban Mar 19, 2026 ▶ 34:19 FULL INTERVIEW: Mark Cuban on Robots, AI, Self-Driving, and Advice to Students
Ricks: PBM rebate incentives should be eliminated as unethical
“These PBMs and there's some group purchasing organizations like this. That should go away. And I think health is different than other commodities. It's probably has a much more important social role in deciding that the smallest, the little guy gets the worst …”
Dave Ricks Nov 11, 2025 ▶ 39:48 Dave Ricks, CEO of Eli Lilly, on GLP-1s and the business of pharma
CHEEKY PINT Assertion Partly supported
Ricks: Insurers initially refused to cover Eli Lilly's discounted generic insulin
“In the first year, no formularies covered this. So it was really only for that cash payer. No insurance company picked it up, even though it was dramatically cheaper. Now it's about half of the volume, but still half not because that model of this margin sprea…”
Dave Ricks Nov 11, 2025 ▶ 44:56 Dave Ricks, CEO of Eli Lilly, on GLP-1s and the business of pharma
20VC Opinion
Frankel: Pharmacy benefit managers hold huge market caps while adding no value
“And these are these legacy companies, a great example of them is the PBMs, the Pharmacy Benefit Managers. Companies that were very innovative 40 years ago, So a PBM connects the pharmacy to the insurer. You know, 40 years ago or 30 years ago, they were great c…”
David Frankel Oct 14, 2024 ▶ 40:45 David Frankel, MP @Founder Collective: Investing Lessons from Seeding Coupang, Pillpack & Suno|E1214 · 20VC with Harry Stebbings
ALL-IN Assertion Partly supported
Eli Lilly retains only one-third of gross drug prices after PBM cuts
“Two thirds of actually our gross price goes to PBMs and insurance companies. So of the gross price that's often quoted, the net for us is about a third of that.”
Dave Ricks Oct 8, 2024 ▶ 45:06 Dave Ricks, CEO of Eli Lilly | The All-In Interview
a16z Assertion Supported
Cuban: Three PBMs control 80% to 90% of the drug market
“And there are three of them that dominate the industry with 80, 90% market share.”
Mark Cuban Mar 5, 2024 ▶ 9:59 Sharks Never Stop Swimming: A Conversation with Mark Cuban
a16z Assertion Supported
Cuban: PBMs exclude $700 biosimilar Usimri to protect drug margin revenues
“Humira is about 8000 dollars a month. Six to 8000 dollars a month. USIMRI is about 700 dollars a month. But they won't add USIMRI to their formularies because they don't want to use the revenue in the margin.”
Mark Cuban Mar 5, 2024 ▶ 10:33 Sharks Never Stop Swimming: A Conversation with Mark Cuban
a16z What-if
Cuban: Five Fortune 50 companies leaving major PBMs would force immediate systemic reform
“If five of the Fortune 50 companies walked away from the big three insurance companies and the big three PBMs, they'd have to change their business models, and immediately, immediately the entire healthcare system would change.”
Mark Cuban Mar 5, 2024 ▶ 13:04 Sharks Never Stop Swimming: A Conversation with Mark Cuban
ACQUIRED Assertion Supported
Pharmacy benefit managers managed benefits for 266 million Americans in 2016
“PBMs manage pharmacy benefits for two hundred and sixty-six million Americans, and that number's old. That's as of twenty-sixteen.”
Ben Gilbert Jan 22, 2024 ▶ 1:28:12 Novo Nordisk (Ozempic) · Acquired
20VC Disclosure
TJ Parker: PillPack received termination notices from all major PBMs in 2015
“And through 2015 we got termination notices from all of the major PBMs, right, very obviously.”
TJ Parker Jun 5, 2023 ▶ 50:41 TJ Parker: Building PillPack, The First E-Commerce Pharmacy, to Amazon's $1B Acquisition | E1022 · 20VC with Harry Stebbings
Scotti: Americans Blame Big Pharma but Actually Suffer from Big PBMs
“All the time you hear Americans, you know, close to you walking around complaining about Big Pharma, and you, what you hear them complaining about is Big Pharma. What they're actually complaining about that they don't know is Big PBM and Big Pharmacy.”
Kimmy Scotti Jan 26, 2023 ▶ 11:31 Kimmy Scotti: How to Spot (and Build) the Next Big Thing · Joe Lonsdale
Evans: Pharmacy Benefit Managers exist purely to skim off the healthcare industry
“There's this weird thing Americans created called PBM. Is it PBM, the pharmaceutical, the kind of, there's this Entity that basically sits between the insurers and pharmaceutical companies and aggregates orders and bargains. And this is like a, you know, multi…”
Benedict Evans Jul 25, 2022 ▶ 13:19 When the point of leverage changes
20VC Insight
Frankel: Pharmacy e-commerce is a binary 'scale or die' business model
“The distributors, the drug distributors who control a lot of the markets don't take you that seriously. You don't get the financial breaks that much, much larger customers get unless you're reaching a certain scale. The PBMs certainly don't take you very serio…”
David Frankel Sep 17, 2018 ▶ 18:25 20VC: Lessons Learned Scaling PillPack from Seed to Amazon Acquisition, Why Investors Should Spend More Time Assessing Human Capital Risk Taken by Founders & The Right Way To Think About Capital Efficiency in Scaling with David Frankel, Managing Partner @

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