Protein
topic on 9 shows · 13 statements across 11 episodes
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13 statements about Protein, every show
Socher: AI hallucinations can be helpful when exploring novel proteins
“But I do think hallucinations can be also very helpful for AI when you want it to explore novel kinds of proteins.”
Chu: High-throughput single-cell proteomics will power next-gen biological models
“RNA is amazing. It foreshadows which proteins are going to get made, but protein by and large are the functional units in a cell. Not only does their abundance matter, their post-translational modification matter, their localization in a cell matter. If you ca…”
Rives: ESM Fold has predicted structures for over 1.1 billion proteins
“So we folded over 1.1 billion proteins and predicted their structures and identified kind of features connecting all of them through mechanistic interpretability.”
Supercool Earth's formulation contains only protein and no living cells
“One distinction, too, is that our formulation is protein only. It doesn't contain any bacteria or anything or fungal cells in it, and so proteins are made by microbes, and they, in order to persist in the environment, the proteins need the microbes around to b…”
Supercool Earth engineers microbes to express active ice-nucleating proteins
“What we're doing with our technology is we're taking natural proteins and encoding them into microbes that we engineered to make the proteins at high levels and maintain their activity”
Current Models Fail to Predict Protein Conformational Dynamics and States
“Proteins are not static. They move, they take different shapes based on their energy states. And I think we are also not that good at understanding the different states that the protein can be in and at what frequency, what probability.”
Lyon: Aim for 100g Daily Protein, Split 50g Morning and Night
“What she is doing is she's having around a hundred grams of protein a day. Make it simple. 50 grams in that first meal, 50 grams in that last meal.”
Dr. Rhonda Patrick: Minimum protein needed to prevent muscle catabolism is 1.2g/kg
“It turns out using new techniques that are more sensitive that in order to just prevent your body from like pulling from, you know, your skeletal muscle to get amino acids, the minimum amount of protein needed to take in is actually 1.2”
Patrick: Physically active individuals need 1.6g of protein per kg daily
“And they also did some studies looking at, well, what if you're physically active, right? You're causing damage to your muscle. You're using a lot of energy. I mean, lots of things going on. That number goes up to 1.6 grams of protein per kilogram body weight.”
Kumar: Dairy is the cheapest protein source known to humans
“Dairy is the cheapest source of protein known to human. It's the cheapest.”
Klane: Replacing fat and sugar with protein makes frozen desserts icy
“What makes ice cream so smooth and have this great mouthfeel when you eat it is fat and sugar. And we wanted to remove or reduce those items and add in protein. And so we were taking out a lot of the key components that does make ice cream so delicious. And th…”
Murdock: DeepMind mapped all 200M known proteins using AlphaFold
“We've used AlphaFold now to map all two hundred million proteins known to science, or two hundred million proteins known to science, and we've made that available to everyone.”