Exercise
topic on 8 shows · 13 statements across 12 episodes
American Optimist 
the Knowledge Project 
Lenny's Podcast 
Capital Allocators 
the a16z Podcast 
All-In 
TBPN 
20VC
13 statements about Exercise, every show
Mares: No US healthcare payer covers exercise for heart disease prevention
“And yet, if you look at our healthcare system, nothing in the healthcare system thinks about someone who is at risk of heart disease exercising as a healthcare intervention. No payer pays for it. No one incentivizes you to do that.”
Bryan Johnson: Sleep is the single biggest health optimization power law
“Sleep is, like, by far and away the biggest power law. Then exercise, number two, diet, number three.”
Mares: Exercise and sleep treat chronic conditions better than pharmaceuticals
“If you look at studies, they show that exercise, sleep supplements, all these things actually work better for treating many chronic conditions than, you know, SSRIs or any such sort of other like pharmaceutical intervention.”
Belmonte: Exercise creates cellular gene expression changes similar to Yamanaka factor pulses
“We have compared what are the changes in the cell between exercise and the short pulses of Yamanaka factors. And you couldn't believe the similarities in the changes in gene expression that exercise does, and how overlap these changes happen when we do the Yam…”
Exercise and Dancing Outperform Psychotherapy for Treating Mild to Moderate Depression
“And the reason is, is they've measured things. You know what better for mood, for mild to moderate depression than psychotherapy or antidepressants? Dancing. Yeah. Exercise. Dancing.”
Exercise Outranks Sleep Because It Can Compensate for Sleep Deprivation
“And by the way, exercise can forgive a lot of sins, including lack of sleep. That's why I start with that. And I don't make the sleep the most important. I actually think it's exercise.”
Eyal: Exercise is a routine, not a habit, requiring conscious thought
“There's a difference between habits and routines. And a lot of things that people think are habits are not really habits. So like I was going to say, you know, exercise, I used to be clinically obese and now I exercise, but that's not technically a habit becau…”
Franceschetti: Avoid late-day exercise to allow body temperature recovery before sleep
“But so you don't want to do exercise or it's not recommended to do exercise in the second part of the day because you accelerate your heart rate. You accelerate your body temperature, right? So you create a bunch of changes inside your body, and then your body…”
Attia: Meditation is not as essential as exercise, nutrition, or sleep
“I don't think meditation per se is essential in the way that I would say exercise is essential and reasonable nutrition And adequate sleep are essential.”
Sinclair: Hyperbaric cycling benefits stem from pseudo-hypoxia mimicking exercise
“And what I think is going on is that it's not the high pressure that's important. It's the decrease that you're becoming pseudo hypoxic. Your body thinks it's running out of oxygen when it's just coming down from a high level. And my lab has shown in mice that…”
Sinclair: Combining exercise and NMN doubled running endurance in mice
“In the animal studies in my lab, when we gave NMN, this molecule that I take every day, to a mouse that was sedentary, didn't have a wheel, didn't run, it could run further, ok?
And we actually have human data that's looking really promising in that direction …”
Spielman: Adding 30 to 50 yearly workouts delivers outsized marginal benefits
“So if you can squeeze an extra 30, 40, 50 workouts in a year, at the margins is really where the benefits are made, both physically, mentally, and emotionally.”
Oakley: Exercise produces BDNF, stimulating dendritic spine growth and learning
“What exercise does is it helps produce
Brain-derived neurotropic factor in your, you know, in your brain, and this is kind of like a fertilizer that helps dendritic spines grow.
In other words, it helps make new connections.”