Gut Microbiome

“Drastically changing the diet, also putting way more fiber in all of a sudden, will just make you gassy or bloated, because your gut is not used to that, and your microbes suddenly get all these foods.”

“If you have about 30 different types of fruit and vegetable a week, then you're really in a good window where there's so much variety of different foods that there can be a variety of different microbes eating them in your gut, which then contributes to your h…”

“So we see especially small kids and seniors in studies that they have a harder time going back to their microbiome after a round of antibiotics. Then we have all the adults in the middle area of this. For them, it's like fifty-fifty. Some of them will actually…”

“And it's a mixture of alcohol annoying the immune cells, alcohol not being good on the nerve cells, alcohol getting chaos into the microbiome, so all of this comes together and gives you this weird, weird text message on your toilet in the next morning saying,…”

“Like I was reading a study the other day about how your micro . Microbiome. Your microbiome in your gut is actually contagious from a person to person, even if you and I never share a drink.”

“If you are trying to benefit the microbiome, you want to bring up multiple strains of beneficial bacteria simultaneously. If you overfeed One strain. You actually can just create a new imbalance.”

“And this, these microbes have a 150 times more genes than are in the human genome. They have about three million genes.”

“They looked at carnitine, which is a compound that is found in red meat. This carnitine is metabolized by the microbiome to form TMA. It's a compound. TMA is then oxidized in the liver to form TMAO, and TMAO causes a reduce in reverse cholesterol transport and…”

“They took pairs of twins that were discordant for obesity. One twin obese and one twin was... And they transplanted their microbiome into germ-free mice. Germ-free mice are mice that are born and raised in sterile conditions, and they don't have a gut microbio…”

“Fecal transplants have been used, they, their claim to fame is by treating Clostridium difficile infections... You indeed transplant stool into these people, and that transplant works mainly because their microbiome is so depleted and it's like, you know, cult…”

“You get this distribution of bacteria in your gut. That even when you go someplace else, it changes in abundance, but it doesn't change in presence or absence, so it bumps us back when you get to a different place.”