“You get this distribution of bacteria in your gut. That even when you go someplace else, it changes in abundance, but it doesn't change in presence or absence, so it bumps us back when you get to a different place.”
quote is from the automated transcript, cleaned for reading:
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More from David Zeevi
Insight
Zeevi: Identical foods cause vastly different glucose spikes across individuals
“So two people eating the same loaf of white bread, one would really spike their glucose and one would really stay flat. And that's true even if you normalize the responses to the responses to glucose. So you have just to see if, so, so, so even foods are not c…”
David ZeeviAug 22, 2018▶ 9:16David Zeevi on Personalized Nutrition Based on Your Gut Microbiome · Y Combinator
Insight
Zeevi: Fecal transplants work for depleted microbiomes but may fail in healthy guts
“Fecal transplants have been used, they, their claim to fame is by treating Clostridium difficile infections... You indeed transplant stool into these people, and that transplant works mainly because their microbiome is so depleted and it's like, you know, cult…”
David ZeeviAug 22, 2018▶ 24:26David Zeevi on Personalized Nutrition Based on Your Gut Microbiome · Y Combinator
AssertionContradicted
Zeevi: Modern daily sugar consumption equals annual sugar intake in 1700
“The annual consumption in 1700 is the daily consumption today.”
David ZeeviAug 22, 2018▶ 3:28David Zeevi on Personalized Nutrition Based on Your Gut Microbiome · Y Combinator
AssertionSupported
Zeevi: Gut microbes metabolize red meat carnitine into atherosclerosis-causing TMAO
“They looked at carnitine, which is a compound that is found in red meat. This carnitine is metabolized by the microbiome to form TMA. It's a compound. TMA is then oxidized in the liver to form TMAO, and TMAO causes a reduce in reverse cholesterol transport and…”
David ZeeviAug 22, 2018▶ 18:07David Zeevi on Personalized Nutrition Based on Your Gut Microbiome · Y Combinator
AssertionSupported
Zeevi: Mice receiving obese twin microbiomes become obese on identical diets
“They took pairs of twins that were discordant for obesity. One twin obese and one twin was... And they transplanted their microbiome into germ-free mice. Germ-free mice are mice that are born and raised in sterile conditions, and they don't have a gut microbio…”
David ZeeviAug 22, 2018▶ 20:22David Zeevi on Personalized Nutrition Based on Your Gut Microbiome · Y Combinator
AssertionSupported
Zeevi: Obesity surged exactly when federal guidelines pushed carbs over dietary fat
“And if you look at their stats, you can see that people did consume more carbs and less fat. And just when they started consuming more carbs and less fat, did this epidemic of obesity and diabetes begin?”
David ZeeviAug 22, 2018▶ 41:23David Zeevi on Personalized Nutrition Based on Your Gut Microbiome · Y Combinator
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