Drug Development
topic on 8 shows · 18 statements across 17 episodes
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18 statements about Drug Development, every show
Rao: Anthropic's AI is accelerating clinical study reporting and drug development paperwork
“A lot of what we're doing today is helping to speed up The drug development process, right? A lot of the paperwork and clinical studies reports and things like that that are needed to be done. AI and our solutions in particular are helping to rapidly accelerat…”
Carnell: AI will speed drug breakthrough timelines from 3-5 years to under 2
“The sheer ability to be more comprehensive and complete in our hypothesis set, and then the sheer ability to run Experimentation at a scale that's unprecedented, I think practically means we are going to be able to speed breakthroughs from timelines that would…”
Ricks: Developing a drug costs $4B, with over 60% spent in Phase 3
“The final stage of testing, the average drug costs three and a half, four billion to make more than 60% of that is the last step.”
Hsu: Physical synthesis and testing will remain AI drug discovery's bottleneck
“If we play this out, right? And let's say these AI models work, right? And you can make a trillion binders in silico that will, you know, be exquisite drug matter, right? We still need to make these things physically and test them in animals and hopefully pred…”
Horowitz: Drug development funding depends on an active M&A market
“It's pretty impossible to do drug to fund drug development if there's no M&A market.”
Horowitz: a16z supports regulation in crypto, drug development, and finance
“We're, you know, in representing little tech, we're not a pure libertarian, anti-regulatory kind of You know, force here. We think we need regulation in places. We certainly need it in drug development. We certainly need regulation in crypto and financial serv…”
Pande: Regulatory delays in drug approvals cause preventable deaths
“If you don't let the drug through, we're actually killing people right now by not getting these advances through, and I think human beings aren't very good at sort of holding that in their head.”
Developing a new drug takes 10 to 15 years on average
“These are averages of averages, of course, but on average, it could take anywhere between 10 to 15 years to develop a drug to get it to patients.”
Friedberg: Drug development costs are rising while annual approvals fall
“If you look at the number of approved drugs every year and the cost per drug is going the wrong direction, and the number of drugs per year is going in the wrong direction.”
Koller: Partnering on existing drug assets can shave two to five years
“And that can usually say shave off, you know, two, three, maybe even five years from the development of a program because you've already made the drug. Sometimes you've already put it in people. You've shown that it's safe. You have a good biomarker for when i…”
Wong: Drug development enjoys relatively strong value capture via pricing
“Drug development is one of the sectors that has relatively good value capture via pricing.”
Rod Wong: Payer pushback on drug pricing is biotech's top long-term risk
“You know, I think one of the things I'm most concerned about is payers and the pressure that we're seeing on paying for innovation in drug development. That's probably my number one long-term concern.”
Solomon: Unlike autonomous vehicles, biotech AI must vastly outperform human experts
“For autonomous vehicles, you have experts, and every driver that can drive a car, you can ask whether an autonomous vehicle drives as good as a driver, like me and you. For drug development, even the best scientists in the world, they don't know, as we mention…”
Abernethy: Testing cancer drugs in dogs saves tens of millions per drug
“The whole message that really I walked away from that conference with was that if we now embedded into the drug development process for human drug development a better understanding of how those drugs performed in dogs, we could save many tens of millions of d…”
Hynes: Overly narrowing healthcare analysts' focus blinds them to 10-year industry changes
“The reason why 12 is enough is it's a very long cycle industry. So it is an industry that is, even though there's a lot of change happening, that change happens over 10 years to bring a drug to the market. And so we want to make sure we're covering all the com…”
Conde: Only one in 10,000 drug compounds becomes a product
“In this world, it's one in 10,000 becomes a product.”
Large pharma relies on acquisitions rather than internal drug research
“Large pharma is not really the research engine anymore, and that a lot of the large pharma actually will acquire more than develop themselves.”