Diffusion Models

topic on 8 shows · 33 statements across 21 episodes

the Y Combinator Startup Podcast Cheeky Pint Latent Space No Priors A Product Market Fit Show the MAD Podcast the a16z Podcast All-In

33 statements about Diffusion Models, every show

LATENT SPACE Assertion Not checkable as stated
Feinberg: GANs failed for protein modeling due to mode collapse before diffusion emerged
“For all the same reasons that those models were really tricky to train for images. Mode collapse was the most famous sort of problem. They didn't work very well for proteins or protein ligand systems. And we sort of had to wait for the right primitive to get c…”
Evan Feinberg Jun 30, 2026 ▶ 1:07:32 🔬 "The Most Innovative Diffusion Research Is Happening in Drug Discovery, Not Image Generation"
CHEEKY PINT Assertion Not checkable as stated
Staniszewski: ElevenLabs applied transformer and diffusion concepts to voice
“And here credit to my co-founder, Piotr, who effectively came with that new idea of how you can now create voice models, which are both reliable, high quality, quick, where you would bring a lot of the ideas from transformer models, from diffusion models into …”
Mati Staniszewski Apr 14, 2026 ▶ 1:47 The world of voice AI, with Mati Staniszewski of ElevenLabs
Welling: Diffusion Models Share Exact Mathematics With Non-Equilibrium Stochastic Thermodynamics
“It turns out that the mathematics that we use for diffusion models, but even for reinforcement learning, for Schrodinger bridges, for MCMC sampling, has the same mathematics as this theory, this physical theory of non-equilibrium Systems.”
Max Welling Feb 25, 2026 ▶ 4:59 🔬Max Welling: Materials Underlie Everything
MAD Opinion
Text diffusion models will not replace autoregressive Transformers at state-of-the-art
“So it is a interesting direction to go into these diffusion, diffusion models as alternative to the auto regressive transformers, but it is not I would say the replacement at the state of the art.”
Sebastian Raschka Jan 29, 2026 ▶ 12:57 State of LLMs 2026: RLVR, GRPO, Inference Scaling — Sebastian Raschka
MAD Prediction Held up
Major AI firm will launch a frontier text diffusion model in 2026
“I think one company will launch a big diffusion model this year.”
Sebastian Raschka Jan 29, 2026 ▶ 13:07 State of LLMs 2026: RLVR, GRPO, Inference Scaling — Sebastian Raschka
NO PRIORS Prediction Held up
Guo: Alternative AI Architectures Like SSMs Will Be Tested
“And like, there's enough capital out there to test them, be they like diffusion or SSMs or whatever. And that's going to happen this next year.”
Sarah Guo Dec 19, 2025 ▶ 23:15 No Priors Ep. 144 | The 2026 AI Forecast with Sarah & Elad
a16z Opinion
Sherman Wu: Combining language and diffusion models is an anti-pattern
“Yeah, I think you're totally right. It's an anti-pattern. It's pretty tough to pull off.”
Sherman Wu Nov 28, 2025 ▶ 42:59 How OpenAI Builds for 800 Million Weekly Users: Model Specialization and Fine-Tuning
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Diffusion Models Achieve 80% of Autoregressive Quality at One-Tenth the Cost
“Diffusion models today are, I would say, 80 to 90% of the quality at one-tenth the cost and latency.”
Deedy Das Nov 14, 2025 ▶ 1:05:50 Anthropic, Glean & OpenRouter: How AI Moats Are Built with Deedy Das of Menlo Ventures
Left-To-Right Autoregressive Reasoning Is Suboptimal for AI Code Generation
“Left to right reasoning for code doesn't actually really make sense, because in code, we don't, like, we might sometimes write code left to right, but after you write code, you go up and down and figure out, hey, is this variable set? Did I do this? There are …”
Deedy Das Nov 14, 2025 ▶ 1:06:31 Anthropic, Glean & OpenRouter: How AI Moats Are Built with Deedy Das of Menlo Ventures
a16z Prediction Not checkable as stated
Hoffman: Future AI will combine LLMs and diffusion models via unified fabric
“But the thing that people on track is it's going to be LMS and diffusion models. And I think other things with a fabric across them.”
Reid Hoffman Oct 20, 2025 ▶ 28:03 Reid Hoffman on AI, Consciousness, and the Future of Labor
a16z Assertion Not checkable as stated
Casado: AI succeeds by driving content creation marginal costs to zero
“So, so the diffusion markets are all working. So any area where you bring the marginal cost of creating something, a piece of content to zero is clearly working and creating an image, creating music, you know, creating speech.”
Martin Casado Sep 3, 2025 ▶ 26:48 Jack Altman & Martin Casado on the Future of Venture Capital
Ermon: Adapting Pretrained Causal LLMs to Diffusion Models Is Difficult
“The challenge is that, yeah, the training objective is quite different because you are training based on denoising as opposed to next token prediction. Diffusion models are not causal and that is also kind of problematic. I mean, it's a big advantage of diffus…”
Stefano Ermon Aug 4, 2025 ▶ 7:29 ⚡️Mercury: Ultra-Fast Diffusion LLMs — Estefano Ermon, CEO Inception Labs
Ermon: Diffusion LLMs Can Reuse Standard Architectures and Datasets
“Well, you can use architectures. I think that at least the shapes you, that, that can be leveraged. So you don't have to reinvent and necessarily completely different neural network architectures can, a lot of the data can be used. Like I think perhaps there a…”
Stefano Ermon Aug 4, 2025 ▶ 8:49 ⚡️Mercury: Ultra-Fast Diffusion LLMs — Estefano Ermon, CEO Inception Labs
Ermon: Diffusion models excel at infilling due to bidirectional context
“Diffusion models. Not surprisingly, they work pretty well at the infilling where you really need to be able to use context to the left and to the right.”
Stefano Ermon Aug 4, 2025 ▶ 12:01 ⚡️Mercury: Ultra-Fast Diffusion LLMs — Estefano Ermon, CEO Inception Labs
LATENT SPACE Assertion Supported
Ermon: Diffusion LLMs Pareto-dominate autoregressive models on inference efficiency
“On the inference side, what we're seeing is that diffusion models are much more efficient. We're actually able to Pareto dominate autoregressive models. If you think about the typical trade-off between throughput versus latency, which you kind of like cannot, …”
Stefano Ermon Aug 4, 2025 ▶ 14:30 ⚡️Mercury: Ultra-Fast Diffusion LLMs — Estefano Ermon, CEO Inception Labs
LATENT SPACE Prediction Not checkable as stated
Ermon: Diffusion models could become the dominant architecture over autoregressive models
“I'm pretty optimistic about a future where diffusion models Can become the dominant solution. I've seen it happen before with GANs a few years ago, so I wouldn't be surprised if that's the case also here.”
Stefano Ermon Aug 4, 2025 ▶ 18:35 ⚡️Mercury: Ultra-Fast Diffusion LLMs — Estefano Ermon, CEO Inception Labs
LATENT SPACE Prediction Not checkable as stated
Ermon: Power constraints will drive diffusion models to replace frontier LLMs
“If it happens, it's gonna be driven by efficiency. Like we're all constrained by essentially power. And if you have, I mean, at the end of the day, it's all an inference game, right? Okay. Training is expensive, but then the thing that matters is being able to…”
Stefano Ermon Aug 4, 2025 ▶ 23:42 ⚡️Mercury: Ultra-Fast Diffusion LLMs — Estefano Ermon, CEO Inception Labs
a16z Disclosure
Kumar: Sesame is developing diffusion-based audio generation models
“We are also working, by the way, on kind of ideas that make the audio generation part diffusion.”
Ankit Kumar Mar 15, 2025 ▶ 1:06:57 Building the Next Generation of Conversational AI
Field: AI struggles with design because diffusion and LLMs remain unmerged
“It's, I think maybe the reason why these models are not great design yet, it's like on the art side you've got diffusion, on the problem solving side you've got LMs, and it's not clear that people have figured out how to, you know, marry techniques together ye…”
Dylan Field Mar 13, 2025 ▶ 7:06 Figma's Dylan Field: Exploring the idea maze, vibe coding, and the power of “locking in” · Y Combinator
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Consistency Models Generate High-Quality Images in a Single Pass
“With the regular diffusion models that we all know and love, they have to iterate multiple times generally to generate a good image. Whereas The, these consistency models are designed so they can generate a good image with only one pass through the network.”
RJ Honicky Nov 2, 2024 ▶ 3:22 [Paper Club] Intro to Diffusion Models and OpenAI sCM: Simple, Stable, Scalable Consistency Models
LATENT SPACE Assertion Supported
Cosine Noise Schedules Eliminate Wasted Backward Steps in Diffusion Models
“They found in this paper that it's actually inefficient, that you end up with a lot of wasted a way wasted backwards process backwards diffusion steps that you don't need and you can cut out a whole bunch of it just by using a cosine schedule.”
RJ Honicky Nov 2, 2024 ▶ 4:44 [Paper Club] Intro to Diffusion Models and OpenAI sCM: Simple, Stable, Scalable Consistency Models
Inconsistent Diffusion Trajectories Drive the Need for Consistency Models
“The locations that you're learning are not basically on the same in the, in this latent space. They're not in the same trajectory As each other, right? So they like and this causes a lot of inefficiency, and that's sort of the whole point to this, the, these …”
RJ Honicky Nov 2, 2024 ▶ 9:59 [Paper Club] Intro to Diffusion Models and OpenAI sCM: Simple, Stable, Scalable Consistency Models
LATENT SPACE Assertion Supported
Probability Flow ODE Traces Maximum Likelihood Path Deterministically in Diffusion
“And then this probability flow ODE is sort of a deterministic version that looks at what is the maximum likelihood path If I started at that trajectory, right?”
RJ Honicky Nov 2, 2024 ▶ 15:08 [Paper Club] Intro to Diffusion Models and OpenAI sCM: Simple, Stable, Scalable Consistency Models
Large Step Sizes in Discrete ODE Solvers Cause Trajectory Errors
“So if this Delta T here is very big, you see it goes, like, far from XT to X minus Delta T, then the error that It can have is very big and that can put it on a different trajectory. So you get the wrong trajectory.”
RJ Honicky Nov 2, 2024 ▶ 25:30 [Paper Club] Intro to Diffusion Models and OpenAI sCM: Simple, Stable, Scalable Consistency Models
Howard: Diffusion should be used to sketch answers before generating tokens
“The idea of, like, there should be a piece of the generative pipeline which is, like, thinking about the answer and coming up with a sketch of what the answer looks like before you start out putting tokens. That's where it kind of feels like diffusion ought to…”
Jeremy Howard Aug 17, 2024 ▶ 1:09:11 Answer.ai & AI Magic with Jeremy Howard
Standard diffusion models fail enterprises over data indemnity and product distortion
“If you typically use any of the diffusion models out there are two large problems for large enterprises. The first one being it's trained on no one knows which data. So even the companies don't know on which data. So it's like for Austin, it doesn't make sense…”
Shubham Mishra Jul 22, 2024 ▶ 13:01 In 2019, he went all-in on AI, grew to $3M ARR in 2 years—then to $85M ARR in 5. | Shubham Mishra... · PMF Show
ALL-IN Assertion Supported
Altman: Best text models are autoregressive while best video models use diffusion
“As far as I know, all the best text models in the world are still autoregressive models and the best image and video models are diffusion models.”
Sam Altman May 10, 2024 ▶ 32:50 Sam Altman: Getting Fired (and Re-Hired) by OpenAI, Agents, AI Copyright issues
NO PRIORS Insight
Field: AI design tools require a hybrid of diffusion models and LLMs
“When do you want like sort of an LM versus diffusion model solution for something and design is maybe you can define it as like art applied to problem solving. there's many different definitions of design. but I love that one. It's one that I've been thinkin…”
Dylan Field Mar 14, 2024 ▶ 13:55 No Priors Ep. 55 | With Figma CEO Dylan Field
NO PRIORS Prediction Not checkable as stated
Field: Text prompting diffusion models is not the end-state generative UI.
“There's no way that having to remember all these different sort of like magical phrases to summon the right image via diffusion model Is the end state, right? And yeah, maybe there's something where you draw some shapes and you add a prompt, but like, that sti…”
Dylan Field Mar 14, 2024 ▶ 18:26 No Priors Ep. 55 | With Figma CEO Dylan Field
a16z Insight
Blattman: High batch sizes are critical for training diffusion models
“So for diffusion models, it's really important to have a high batch size, because the gradients gets, like, you can approximate the gradient, which thrives the learning much better if the batch size is higher. And especially for diffusion models, it's like rea…”
Andreas Blattman Feb 17, 2024 ▶ 17:43 Text to Video: The Next Leap in AI Generation
LATENT SPACE Assertion Not checkable as stated
Patel: Several companies make tens of millions from adult AI models
“I think there's a couple companies who make, Tens of millions of dollars of revenue from, yeah, from LLMs or diffusion models for porn”
Dylan Patel Dec 5, 2023 ▶ 29:48 The State of Silicon and the GPU Poors - with Dylan Patel of SemiAnalysis
NO PRIORS Prediction Not checkable as stated
Gil: More Startups Will Train Custom Diffusion Models than LLMs
“And so you can actually imagine that in the language world, you're going to have a lot more platforms that people build on in the diffusion model world image, video, et cetera, you're going to have more people kind of grow their own.”
Elad Gil Nov 30, 2023 ▶ 13:48 No Priors Ep. 42 | With Sarah Guo and Elad Gil
a16z Prediction Not checkable as stated
Field: Code-based AI models will generate UI designs better than diffusion
“One outcome might be that we find more success with models that are similar to CodePilot than you do with like a diffusion model, for example, when you're trying to figure out how do you actually create designs using AI systems.”
Dylan Field Sep 25, 2023 ▶ 12:17 Democratizing Design with Figma's Dylan Field

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