Aging

“With existing technology and giving it more data and more compute, we can already cure a lot of diseases. We can already cure many of the aspects of aging. We can already build better fusion like reactors and systems. We can already create new materials.”

“Aging is not a linear process. We feel that a 50 to a 60 to a 70 to a 80, the aging will move in a certain graph. It doesn't. It comes with its own blips. And sometimes the crash is very, very exponential.”

“I do think it is a very solvable problem. When we figure out what causes aging, I think we'll find it's incredibly obvious. It's not a subtle thing. The reason I say it's not a subtle thing is because all the cells in your body pretty much age at the same rate…”

“My view on this is not that I think healthy, 30 year olds are going to be getting these soon, but eventually many people become patients. Aging is like the correlate of kind of everything getting worse. And so there's some critical age where it kind of crosses…”

“I think aging is in a somewhat similar space in that it's a massive multifactorial disease, and if we rely on existing modality approaches, it would just be an uphill battle to try and treat it.”

“As you age, part of your brain that keeps you well-balanced atrophies, and you can't maintain the balance very well, so kids are very good at this. As you age, you get worse, ok?”

“Obviously, we want to be able to predict drug toxicity. We want to be able to predict aging. We want to be able to predict why a liver cell becomes cirrhotic when you repeatedly challenge it with ethanol molecules or whatever, right? And, you know, the, these …”

“Other things like cures for aging and stuff like that, like we don't have them yet, but there is no, you know, no laws of physics prevent people, you know, from living indefinitely.”

“When we think about disease, we think of disease as something bad happening to us, but a lot of that stuff is exacerbated with age, and that age itself is like so much of the challenge that we get Cancer and Alzheimer's and type two diabetes with such greater …”

“Every day over a 100,000 people die from aging itself”

“They calculated that the US alone, just by slowing down aging by one year, and making people productive, more productive for one year, would save over the next three decades, 86 trillion dollars, which we waste now on just keeping people alive in a sick state …”

“Eventually born, and this epigenomic information that tells cells how to behave, we think breaks down over time, and that results in diseases, tissue dysfunction, so, you know, you start to look older, you can't clear toxins, you can't think well, your nerve c…”

“Aging was the world's most important problem, the source of the world's greatest amount of suffering, and so on.”

“Making machines smart enough to relieve us of the tedium of having to spend our lives doing things that we wouldn't do if we weren't being paid in order to make the world go around. Yeah, so I wanted that to end. But I always knew that that was only the world'…”

“That would get the average lifespan up to 113 by targeting aging directly rather than targeting individual diseases one at a time. And what's really key too is this would be an additional 30 years of healthy life.”