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Aubrey de Grey

President and CSO, LEV Foundation · 1 appearance on the record.

computed by AI from the episodes · how this works → · full disclaimer →

scientistfounderexecutiveauthorengineer@aubreydegrey ↗LinkedIn ↗levf.org/aubreydegrey ↗Wikipedia ↗

Aubrey de Grey is best known for formulating the Strategies for Engineered Negligible Senescence (SENS) damage-repair framework and co-founding organizations including the SENS Research Foundation and LEV Foundation. He co-authored the book Ending Aging and advocates for biomedical engineering to reverse age-related degeneration in humans.

10statements → 3claims → 1claims resolved → 4/5average certainty → 3.1/5average debate potential →

1 supported 0 partly supported 0 contradicted 2 not checkable as stated how the 3 claims stand · each chip opens the sources

1 prediction · 2 assertions · 3 opinions · 3 insights · 1 disclosure · every statement was checked. The prediction and assertions are the 3 claims: statements the public record can support or contradict. 1 is resolved, and 2 name no date, number or outcome precise enough to check. Everything else (opinions, insights, what ifs, disclosures) can never be settled by the record, so it carries no assessment.

The record, in short

What the tape says about how Aubrey argues and how the claims held up. Everything they said, and everything said about them, is in the tabs below.

Their most notable supported claim

Assertion Supported
De Grey: Amyloid clearance is solved but requires combination therapies for Alzheimer's
“Well, in one case, Alzheimer's disease, that's also, that's very much in clinical trials, and we basically solve the problem. That can now be eliminated. It doesn't have much effect on Alzheimer's disease on its own, but it's a fair bet that in combination wit…”
Aubrey de Grey Jan 2, 2019 ▶ 20:26 a16z Podcast | Defeating Aging with Aubrey de Grey

How they sound: speaking style how? →

229 words/min while actually speaking · 32.6 um and uh per 1k words

No argument clarity score for Aubrey de Grey: no usable question→answer exchanges on raw tape (a fair score needs 8+). We do not score a sample that small. Roundtable and news formats yield far fewer direct exchanges than interviews.

Measured by listening to the audio itself: 3,248 words across 1 episode of raw-level tape, transcribed verbatim with every um and uh kept, each one attributed only where the alignment onto our timed stream is unambiguous. These are measurements of speaking style. We do not rank them: across this corpus, fluency and argument quality are nearly uncorrelated (ρ≈0.2), and smooth talking does not signal clear thinking. How it's measured →

Everything Aubrey de Grey said on the a16z Podcast that made the record, most notable first. Filter by type, assessment or year in the ledger →

Assertion Supported
De Grey: Amyloid clearance is solved but requires combination therapies for Alzheimer's
“Well, in one case, Alzheimer's disease, that's also, that's very much in clinical trials, and we basically solve the problem. That can now be eliminated. It doesn't have much effect on Alzheimer's disease on its own, but it's a fair bet that in combination wit…”
Aubrey de Grey Jan 2, 2019 ▶ 20:26 a16z Podcast | Defeating Aging with Aubrey de Grey
Opinion
De Grey: Peer-reviewed funding is a catastrophe for high-risk scientific research
“Peer review is an absolute catastrophe when it comes to doing anything high risk, high reward, and also for that matter doing anything cross-disciplinary.”
Aubrey de Grey Jan 2, 2019 ▶ 15:50 a16z Podcast | Defeating Aging with Aubrey de Grey
Disclosure
De Grey accepts non-biological longevity solutions if biotech stalls
“I'm quite sentimental about being made out of meat, but at the same time, you know, if the Push came to shove and the work that we do and other people do on the biotech side started to, you know, hit diminishing returns and basically run into the sand and work…”
Aubrey de Grey Jan 2, 2019 ▶ 23:00 a16z Podcast | Defeating Aging with Aubrey de Grey
Prediction Not checkable as stated
De Grey: Earth's carrying capacity will easily outpace population growth
“It seems to me pretty damn clear that the increase in the carrying capacity of the planet over the next century will way outrun the increase in the actual population of the planet.”
Aubrey de Grey Jan 2, 2019 ▶ 25:41 a16z Podcast | Defeating Aging with Aubrey de Grey
Opinion
De Grey: Biological aging is humanity's most important problem
“Aging was the world's most important problem, the source of the world's greatest amount of suffering, and so on.”
Aubrey de Grey Jan 2, 2019 ▶ 2:02 a16z Podcast | Defeating Aging with Aubrey de Grey
Opinion
De Grey: AI is only humanity's second most important problem
“Making machines smart enough to relieve us of the tedium of having to spend our lives doing things that we wouldn't do if we weren't being paid in order to make the world go around. Yeah, so I wanted that to end. But I always knew that that was only the world'…”
Aubrey de Grey Jan 2, 2019 ▶ 2:47 a16z Podcast | Defeating Aging with Aubrey de Grey
Insight
De Grey: Aging research stalled because scientists lacked an engineering mindset
“I realized that a lot of the reason why people were not making progress in postponing the ill health of old age was because they were going about it more as, you know, lifelong basic scientists and not so much as technologists with a more goal-directed kind of…”
Aubrey de Grey Jan 2, 2019 ▶ 4:26 a16z Podcast | Defeating Aging with Aubrey de Grey
Insight
De Grey: Engineering maintenance principles can postpone the ill health of aging
“Any machine, and of course the human body is just a machine, right any machine has moving parts, it does damage to itself as a side effect of its normal operation, so one can use the same principles, the same, like, top-level principles to postpone the ill hea…”
Aubrey de Grey Jan 2, 2019 ▶ 17:28 a16z Podcast | Defeating Aging with Aubrey de Grey
Insight
De Grey: Fast sequencing and data processing do not create fundamental breakthroughs
“Things like the ability to sequence things really fast and really cheaply or the ability to process things usually doesn't actually underpin the fundamental breakthroughs.”
Aubrey de Grey Jan 2, 2019 ▶ 27:09 a16z Podcast | Defeating Aging with Aubrey de Grey
Assertion Not checkable as stated
De Grey: Ray Kurzweil is overly optimistic about current anti-aging methods
“He is actually a lot more optimistic than me with regard to how much we can postpone aging with stuff that already exists today.”
Aubrey de Grey Jan 2, 2019 ▶ 21:52 a16z Podcast | Defeating Aging with Aubrey de Grey

Appearances (1)

EpisodeDateSpeaking time
a16z Podcast | Defeating Aging with Aubrey de Grey Jan 2, 2019 20m
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