The Ledger
Every statement that passed quotation and attribution checks. Mix any filter with any other: certainty 1/5, debate potential 5/5, or both at once.
why aren't all 10 resolved? a statement only gets an assessment when the public record can support or contradict it. opinions and what-ifs never can, and 0 checkable ones are still open, waiting for their date. predictions held up or didn't; assertions are supported or contradicted. on every card: ▮▮▮▮▮ certainty · ▮▮▮▮▮ debate potential. speakers are clickable
De Grey: Amyloid clearance is solved but requires combination therapies for Alzheimer's
“Well, in one case, Alzheimer's disease, that's also, that's very much in clinical trials, and we basically solve the problem. That can now be eliminated. It doesn't have much effect on Alzheimer's disease on its own, but it's a fair bet that in combination wit…”
De Grey: Peer-reviewed funding is a catastrophe for high-risk scientific research
“Peer review is an absolute catastrophe when it comes to doing anything high risk, high reward, and also for that matter doing anything cross-disciplinary.”
De Grey accepts non-biological longevity solutions if biotech stalls
“I'm quite sentimental about being made out of meat, but at the same time, you know, if the Push came to shove and the work that we do and other people do on the biotech side started to, you know, hit diminishing returns and basically run into the sand and work…”
De Grey: Earth's carrying capacity will easily outpace population growth
“It seems to me pretty damn clear that the increase in the carrying capacity of the planet over the next century will way outrun the increase in the actual population of the planet.”
De Grey: Biological aging is humanity's most important problem
“Aging was the world's most important problem, the source of the world's greatest amount of suffering, and so on.”
De Grey: AI is only humanity's second most important problem
“Making machines smart enough to relieve us of the tedium of having to spend our lives doing things that we wouldn't do if we weren't being paid in order to make the world go around. Yeah, so I wanted that to end. But I always knew that that was only the world'…”
De Grey: Aging research stalled because scientists lacked an engineering mindset
“I realized that a lot of the reason why people were not making progress in postponing the ill health of old age was because they were going about it more as, you know, lifelong basic scientists and not so much as technologists with a more goal-directed kind of…”
De Grey: Engineering maintenance principles can postpone the ill health of aging
“Any machine, and of course the human body is just a machine, right any machine has moving parts, it does damage to itself as a side effect of its normal operation, so one can use the same principles, the same, like, top-level principles to postpone the ill hea…”