Friedberg: David Sinclair sold a company to GSK for $720M on failed resveratrol claims
“Years ago he sold a company to GSK saying resveratrol would reverse aging and, you know, he made seven hundred twenty million dollars on that and it didn't end up working”
AI Specialists Will Give Average Users Better Longevity Care Than Elite Clinics
“It's going to be really incredible when the average person with their 10 dollar a month or a ring can get
Even better care from this team of digital specialists than some, you know, public company CEO that's using David Sinclair's like, you know, longevity pro…”
Diamandis: Longevity Escape Velocity Will Be Reached in About 20 Years
“Ray Kurzweil's prediction is 2030, which is insanely close, right? Why? It's because AI is going to help us understand why we age, how to slow it, how to stop it, how to reverse it. George Church puts it at some 15 years out. David Sinclair is in that same are…”
Sinclair: Sirtuin Gene Therapy Extends Lifespan in Mice
“In mice, we do this, and if you do it in the brain of a mouse, they'll live longer. Do it in the body. They can live longer, but we can't genetically modify ourselves.”
Sinclair: Olive Oil and Red Wine Compounds Activate Sirtuins to Improve Health
“And there are actually chemicals within those foods of a Mediterranean diet in olive oil and red wine. That we found in my lab to activate these sirtuins and probably also slow down the clock, but they certainly improve health.”
Sinclair: Research Shows Interventions Can Make an 80-Year-Old Biologically 60
“We're keeping animals and increasingly we're showing with people that you can keep them younger for longer so that when you're 80, you can actually be 60.”
Sinclair: NMN Supplementation Has Prevented Jet Lag for a Decade
“I haven't had jet lag for a decade because I've been able to modulate my own body clock by using these chemicals, which as I mentioned are activating sirtuins and controlling the clock.”
Sinclair: Research Restored Eyesight and Reversed Aging in Mice
“About a year ago, we published that we could reverse the age of an animal. And we restored eyesight to a blind old mouse and cure glaucoma in that animal.”
Sinclair: Team May Reverse Aging in Humans Within 18 Months
“In Canada, we have a non-human primate study for safety to see how that goes, and within the next 18 months, if all goes well, we will be reversing aging in a human, if all goes well.”
Sinclair: Reversing Biological Age Will Eliminate Alzheimer's and Cancer
“Truly reset the age of the body and diseases of aging, like Alzheimer's and heart disease, even cancer will go away if we become young again.”
Sinclair: Longevity tools will extend human lifespan by 5 to 15 years
“And those three combined, I think, are going to dramatically increase human health span and lifespan by somewhere between five and 15 years in our lifetimes.”
Sinclair: Companies he advises are running anti-aging human trials
“A couple of companies that I work with have been doing trials for a number of years now, and they seem to be working as advertised, but it's pretty hard to actually show that they're reversing aging. So we're going off to particular diseases.”
Sinclair: Epigenetic reprogramming could enable five-year biological age resets
“There is actually evidence in a mouse that you can reverse some of those so-called epigenetic analog changes with aging, and that's truly the next frontier in my view, because that really could lead to true Aging reset, and you just go to the doctor every five…”
Sinclair: A 10% cancer reduction saves the U.S. $3-4 trillion
“The economists have calculated that just reducing one major disease, let's say cancer, by just 10%, The U.S. Would save about three, four trillion dollars in the long run.”
Sinclair: Metformin and NAD boosters reduced calculated biological age from 57 to 31
“I took metformin, Kristen mentioned, which is a diabetes drug. I took another molecule that we've worked on called, it raises NAD, we call them NAD boosters, and I saw that my bio-age, according to this algorithm, went down to 31.4 from 57 point something, and…”