StarZero All shows Try the podcast clipper →

David Sinclair

Professor of Genetics, Harvard Medical School · 1 appearance on the record.

computed by AI from the episodes · how this works → · full disclaimer →

academicscientistauthorfounderhost@davidasinclair ↗LinkedIn ↗sinclair.hms.harvard.edu ↗Wikipedia ↗YouTube ↗Instagram ↗

Sinclair researches the molecular biology of aging, focusing on sirtuins, NAD+ precursors, and cellular reprogramming to delay or reverse age-related decline. He authored the bestselling book Lifespan: Why We Age – and Why We Don't Have To and co-founded several biotechnology companies, including Sirtris Pharmaceuticals and Life Biosciences.

5statements → 3claims → 1claims resolved → 3.6/5average certainty → 2.8/5average debate potential → 1said about them ↓

1 supported 0 partly supported 0 contradicted 2 not checkable as stated how the 3 claims stand · each chip opens the sources

2 predictions · 1 assertion · 2 disclosures · every statement was checked. The predictions and assertion are the 3 claims: statements the public record can support or contradict. 1 is resolved, and 2 name no date, number or outcome precise enough to check. Everything else (opinions, insights, what ifs, disclosures) can never be settled by the record, so it carries no assessment.

The record, in short

What the tape says about how David argues and how the claims held up. Everything they said, and everything said about them, is in the tabs below.

Their most notable supported claim

Assertion Supported
Sinclair: A 10% cancer reduction saves the U.S. $3-4 trillion
“The economists have calculated that just reducing one major disease, let's say cancer, by just 10%, The U.S. Would save about three, four trillion dollars in the long run.”
David Sinclair Jan 2, 2019 ▶ 12:25 a16z Podcast | How to Live Longer and Better

Everything David Sinclair said on the a16z Podcast that made the record, most notable first. Filter by type, assessment or year in the ledger →

Disclosure
Sinclair: Metformin and NAD boosters reduced calculated biological age from 57 to 31
“I took metformin, Kristen mentioned, which is a diabetes drug. I took another molecule that we've worked on called, it raises NAD, we call them NAD boosters, and I saw that my bio-age, according to this algorithm, went down to 31.4 from 57 point something, and…”
David Sinclair Jan 2, 2019 ▶ 16:38 a16z Podcast | How to Live Longer and Better
Prediction Not checkable as stated
Sinclair: Longevity tools will extend human lifespan by 5 to 15 years
“And those three combined, I think, are going to dramatically increase human health span and lifespan by somewhere between five and 15 years in our lifetimes.”
David Sinclair Jan 2, 2019 ▶ 4:17 a16z Podcast | How to Live Longer and Better
Prediction Not checkable as stated
Sinclair: Epigenetic reprogramming could enable five-year biological age resets
“There is actually evidence in a mouse that you can reverse some of those so-called epigenetic analog changes with aging, and that's truly the next frontier in my view, because that really could lead to true Aging reset, and you just go to the doctor every five…”
David Sinclair Jan 2, 2019 ▶ 8:38 a16z Podcast | How to Live Longer and Better
Disclosure
Sinclair: Companies he advises are running anti-aging human trials
“A couple of companies that I work with have been doing trials for a number of years now, and they seem to be working as advertised, but it's pretty hard to actually show that they're reversing aging. So we're going off to particular diseases.”
David Sinclair Jan 2, 2019 ▶ 7:36 a16z Podcast | How to Live Longer and Better
Assertion Supported
Sinclair: A 10% cancer reduction saves the U.S. $3-4 trillion
“The economists have calculated that just reducing one major disease, let's say cancer, by just 10%, The U.S. Would save about three, four trillion dollars in the long run.”
David Sinclair Jan 2, 2019 ▶ 12:25 a16z Podcast | How to Live Longer and Better

The other half of the tape: David Sinclair's own voice is left out of every number here. Other people bring the name up 1 time in 1 episode on the a16z Podcast. every mention, with the transcript →

Who brings them up most Tony Robbins 1

Every mention by year

tap a year for its mentions
0011112023episodesmentions
0112023episodes it came up in
000.50.5112023episodesmentions per episode
2023 1 mention in 1 episode

Appearances (1)

EpisodeDateSpeaking time
a16z Podcast | How to Live Longer and Better Jan 2, 2019 4m
Made with StarZero

Turn any episode into a week of clips.

This entire site, over 1,000 episodes transcribed, diarized, checked and made playable, runs on the StarZero media pipeline. Drop in your own episode and the podcast clipper finds the moments worth sharing, cuts them, captions them, and reframes them for every feed.

Try the podcast clipper Learn more