David Sinclair

Everything David Sinclair said on any show that made the record, most notable first. Each card names its show and opens the statement there.

a16z Disclosure

Sinclair: Metformin and NAD boosters reduced calculated biological age from 57 to 31

“I took metformin, Kristen mentioned, which is a diabetes drug. I took another molecule that we've worked on called, it raises NAD, we call them NAD boosters, and I saw that my bio-age, according to this algorithm, went down to 31.4 from 57 point something, and…”

David Sinclair Jan 2, 2019 ▶ 16:38 a16z Podcast | How to Live Longer and Better

a16z Prediction Not checkable as stated

Sinclair: Longevity tools will extend human lifespan by 5 to 15 years

“And those three combined, I think, are going to dramatically increase human health span and lifespan by somewhere between five and 15 years in our lifetimes.”

David Sinclair Jan 2, 2019 ▶ 4:17 a16z Podcast | How to Live Longer and Better

a16z Prediction Not checkable as stated

Sinclair: Epigenetic reprogramming could enable five-year biological age resets

“There is actually evidence in a mouse that you can reverse some of those so-called epigenetic analog changes with aging, and that's truly the next frontier in my view, because that really could lead to true Aging reset, and you just go to the doctor every five…”

David Sinclair Jan 2, 2019 ▶ 8:38 a16z Podcast | How to Live Longer and Better

a16z Disclosure

Sinclair: Companies he advises are running anti-aging human trials

“A couple of companies that I work with have been doing trials for a number of years now, and they seem to be working as advertised, but it's pretty hard to actually show that they're reversing aging. So we're going off to particular diseases.”

David Sinclair Jan 2, 2019 ▶ 7:36 a16z Podcast | How to Live Longer and Better

a16z Assertion Supported

Sinclair: A 10% cancer reduction saves the U.S. $3-4 trillion

“The economists have calculated that just reducing one major disease, let's say cancer, by just 10%, The U.S. Would save about three, four trillion dollars in the long run.”

David Sinclair Jan 2, 2019 ▶ 12:25 a16z Podcast | How to Live Longer and Better

The other half of the tape: David Sinclair's own voice is left out of every number here. Other people bring the name up 1 time in 1 episode across the shows. every mention, with the transcript →

Who brings them up most Tony Robbins 1

Every mention by year

One line per show, most statements first. The link opens David's full record on that show: the calibration, argument clarity, speaking style and every statement made there.

Show	Role there	Eps	Statements	Record
a16zLEDGER	Professor of Genetics, Harvard Medical School	1	5	100% 1/1	full record on the a16z Podcast →