Biotech Industry

topic on 5 shows · 13 statements across 10 episodes

No Priors Capital Allocators Catalyst How I Built This the a16z Podcast

13 statements about Biotech Industry, every show

NO PRIORS Opinion
Chan: Curing disease requires uniting academia and industry via non-profit neutrality
“The sort of neutral nonprofit nature of our work actually helps harness more people to enter this effort. And to actually achieve the mission of, like, understanding the totality of human biology and to cure, prevent, manage all diseases, you actually do need …”
Priscilla Chan Jun 10, 2026 ▶ 19:51 “Curing All Disease by next century is too conservative" - Mark Zuckerberg
a16z Assertion Not checkable as stated
Nuzhna: Biotech regulatory requirements have continuously increased since industry inception
“Since the birth of this industry, we only had increasing regulation over time.”
Lada Nuzhna Nov 14, 2025 ▶ 6:16 The Brutal Truth About Biotech: Why $2B Per Drug Is Killing Innovation
a16z Prediction Not checkable as stated
Nuzhna: Everyone in biotech will use AI within five years
“Everyone will be using AI and biotech industry five years from now.”
Lada Nuzhna Nov 14, 2025 ▶ 0:27 The Brutal Truth About Biotech: Why $2B Per Drug Is Killing Innovation
a16z Assertion Contradicted
Nuzhna: FDA regulation has continuously increased except during the AIDS crisis
“Since the birth of this industry, we only had increasing regulation over time. I think there was like only one time in history of biotech where we made it easier to develop and approve new drugs. And that was during the ACE crisis where AIDS patients were just…”
Lada Nuzhna Nov 14, 2025 ▶ 6:15 The Brutal Truth About Biotech: Why $2B Per Drug Is Killing Innovation
a16z Assertion Not checkable as stated
Biotech funding cycle has shifted away from platforms back to products
“I think the pendulum always swings back and forth between platforms and products and back again. I think we're back in the product cycle”
Jonathan Lim Apr 30, 2025 ▶ 19:10 Biotech CEO on where we are in the fight to cure cancer
CAPITAL ALLOCATORS Assertion Supported
Wong: Biotech is in its second-deepest and second-longest bear market ever
“So we are 18 months into a biotech bear market that's the second worst Correction in the history of the industry, right? The first being the obvious one, the genomics bubble bursting in 2000 to 2003. It's second longest, second deepest.”
Rod Wong Apr 24, 2023 ▶ 11:26 Rod Wong – Empty Rooms: Innovation in Biotech at RTW (Capital Allocators, EP. 310)
CAPITAL ALLOCATORS Assertion Contradicted
Lamont: By 2000 there were 3,000 public biotech companies and 5 approved products
“That there were 3000 public biotech companies, and only five approved products.”
Annie Lamont Mar 7, 2022 ▶ 14:36 Annie Lamont – A Lifetime in Venture, Venture is Eating the Investment World 9 (Capital Allocators, EP. 238)
CATALYST Insight
Lipman: Synbio startups should prioritize niche, high-value markets
“You know, you always want to try to own a larger portion of a small market than try to own a small portion of a large market, at least at the outset. So I think, and that has been the tradition across the biotech industry and across synthetic biology is go for…”
Ari Lipman Jan 18, 2022 ▶ 30:24 Microbes, meat and materials: biotech meets climatetech
Afeyan: Long biotech lifecycles prevent serial entrepreneurship, forcing internal talent creation
“In biotech, these companies have a half-life or a life cycle of, say, 10 years, 15 years. So people don't do one company after another. If they do one company after 1015 years and they succeed, they stop doing it. So you have to create the talent.”
Noubar Afeyan Oct 11, 2021 ▶ 33:04 Moderna and Flagship Pioneering: Noubar Afeyan
CAPITAL ALLOCATORS Assertion Supported
Biotech underperformed tech and matched the S&P 500 over five years
“It's interesting that if you go look at the biotech industry relative or any of the small cap biotech industries relative to the NASDAQ or relative to the S&P, they've underperformed the NASDAQ, so they've underperformed tech the last four or five years. They'…”
Jordi Visser Mar 25, 2019 ▶ 1:09:32 Jordi Visser – Next Generation of Manager Allocation (Capital Allocators, EP.92)
a16z Assertion Contradicted
Nate Chang: Biotech M&A deals totaled $123 billion in 2018
“So in 2018, the industry announced one hundred twenty three billion of MNA transactions.”
Nate Chang Feb 28, 2019 ▶ 9:23 What’s with All the Bio M&A in 2019?: A Quick Take
a16z Assertion Supported
Nate Chang: Biotech M&A reached $94 billion by early 2019
“This year we're at ninety four billion.”
Nate Chang Feb 28, 2019 ▶ 9:30 What’s with All the Bio M&A in 2019?: A Quick Take
a16z Insight
Conde: Engineering principles make later drug programs more valuable than earlier ones
“The second drug is more valuable than the first if you're using engineering principles, because what you learn from example one sort of imbues value to example two and so on and so forth.”
Jorge Conde Jan 2, 2019 ▶ 8:34 a16z Podcast | When (and How) Biology Becomes Engineering

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