Statins
topic on 8 shows · 12 statements across 9 episodes · said 3 times in 2 episodes since 2024
Cheeky Pint 2 
My First Million 1 
American Optimist 
Invest Like the Best 
the a16z Podcast 
All-In 
TBPN 
20VC
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Cheeky Pint 2My First Million 1
2025 2 mentions in 1 episode
2024 1 mention in 1 episode
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12 statements about Statins, every show
Carnell: Existing medicines can reduce middle-aged cardiovascular risk below 10%
“Most middle-aged men and women walking around have somewhere between a 30 and a 50% probability of having a heart attack and a stroke sometime between the time that they turn 40 and the time that they turn 80. And to me, that's tragic because we have the medic…”
Carnell: PCSK9 Inhibitors Have More Favorable Risk-Reward Than Statins
“If you start taking a PCSK nine inhibitor earlier in your life, Which, by the way, I think the risk reward is actually even more favorable than statins in terms of human health, but we know that you won't progress to cardiovascular disease.”
Statins cost Hims & Hers two cents per dose to manufacture
“A statin is, you know, two cents for me to manufacture.”
Chamath Palihapitiya was prescribed statins to treat arterial plaque
“When he discovered some plaque in my arteries, he put me on statins.”
Coogan: Medical practice consistently shifts over time from lifestyle advice to drug prescriptions
“There's some condition that doctors recommend a lifestyle changes for. Then an exciting new medication comes out and over a generation or so, doctors go from demanding the lifestyle change to gesturing at the lifestyle change before prescribing the medication …”
Chamath: GLP-1 weight loss drugs will probably play out like statins
“I do think that these GLP ones, if when we look back on it will probably be like statins.”
Attia: Five percent of patients suffer debilitating side effects from statins
“Statins are a really good drug under this situation. And yeah, five percent of people get really bad debilitating side effects and should never take them.”
Chamath: PCSK9 inhibitors are a next-generation heart disease gene therapy
“If Lipitor, for example, or Crestor, or these statins are not working for you, there's this next generation kind of drug called the PCSK-IX inhibitor, which essentially is effectively a gene therapy that's modeled after this very specific group of folks in the…”
Hillenmeyer: Fungi mutated their own pathways to survive producing statins
“So this fungus that evolved the statin originally had to protect itself by mutating its own cholesterol, and we can see that in the DNA sequence, so we call it a toxin-antitoxin pair.”
Hexagon Bio rediscovered statins and existing drugs using its platform
“So we, for example, rediscovered the statins and some of these existing drugs.”
Hillenmeyer: Hexagon Bio discovered fungal compounds targeting cardiovascular pathways
“So we've seen we rediscovered the statins themselves, as I mentioned, we've seen other drugs evolving in that same kind of cholesterol pathway. And we also see other totally unrelated chemicals in unrelated pathways that could also have an effect on cardiovasc…”