Mice
topic on 4 shows · 8 statements across 6 episodes
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8 statements about Mice, every show
Siren Biotechnology's viral gene therapy effectively cured mice of brain cancer
“So we can massively improve the lifespans of these animals, and for all intents and purposes, cure these mice, ah, of brain cancer”
Friedberg: Yamanaka factors increased mouse lifespan by 107%
“And by the way, when they applied those Yamanaka factors to the mice lived a 107% longer than they were supposed to.”
Sinclair: Sirtuin Gene Therapy Extends Mouse Lifespan in Lab Studies
“And there are seven of these epigenetic regulators, the things that prevent the scratches, and we can turn them on
With gene therapy.
In mice, we do this, and if you do it in the brain of a mouse, they'll live longer.
Do it in the body, they can live longer.”
Sinclair: Sirtuin Gene Therapy Extends Lifespan in Mice
“In mice, we do this, and if you do it in the brain of a mouse, they'll live longer. Do it in the body. They can live longer, but we can't genetically modify ourselves.”
Sinclair: Combining exercise and NMN doubled running endurance in mice
“In the animal studies in my lab, when we gave NMN, this molecule that I take every day, to a mouse that was sedentary, didn't have a wheel, didn't run, it could run further, ok?
And we actually have human data that's looking really promising in that direction …”
Biological interventions can reproducibly extend mouse lifespans by up to 30%
“So we can make mice live about 20 to 30% longer.”
Rapamycin reproducibly extends middle-aged mouse lifespan by 14% on average
“And this is, I would consider this to be one of the first drugs shown to reproducibly extend mouse lifespan. It's a very solid result. It's been done over and over again, and basically they gave this drug to mice starting from middle age, and it boosted their …”