Sinclair: Sirtuin Gene Therapy Extends Mouse Lifespan in Lab Studies
Dr. David Sinclair · Best of 2022: Conversations of the Year · Dec 27, 2022 · at 1:35:08
Harvard geneticist David Sinclair explains how epigenetic regulator genes called sirtuins influence longevity in animal models.
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“And there are seven of these epigenetic regulators, the things that prevent the scratches, and we can turn them on With gene therapy. In mice, we do this, and if you do it in the brain of a mouse, they'll live longer. Do it in the body, they can live longer.”
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