sirtuins

“What we've realized is that in addition to be being antioxidants, they actually turn on those longevity pathways, the sirtuins. They work on mTOR. There's another one called AMPK, which senses blood sugar and energy. And by eating plants that in general Make t…”

“I haven't had jet lag for a decade because I've been able to modulate my own body clock by using these chemicals, which as I mentioned are activating sirtuins and controlling the clock.”

“In mice, we do this, and if you do it in the brain of a mouse, they'll live longer. Do it in the body. They can live longer, but we can't genetically modify ourselves.”

“And there are actually chemicals within those foods of a Mediterranean diet in olive oil and red wine. That we found in my lab to activate these sirtuins and probably also slow down the clock, but they certainly improve health.”

“And there are seven of these epigenetic regulators, the things that prevent the scratches, and we can turn them on With gene therapy. In mice, we do this, and if you do it in the brain of a mouse, they'll live longer. Do it in the body, they can live longer.”