HIV
topic on 4 shows · 8 statements across 7 episodes
American Optimist
the Knowledge Project
How I Built This
the a16z Podcast
8 statements about HIV, every show
Immune resets for leukemia patients have serendipitously eliminated MS and HIV
“There are sort of serendipitous situations where people have had, for example, really severe autoimmune diseases like multiple sclerosis, happen to also have leukemia on the side. For the leukemia, they get an immune system reset, and then they, you know, magi…”
Gallagher: Illegal Reedley biolab held Ebola, HIV, and tuberculosis samples
“Eventually it was discovered that these vials contained Ebola HIV, tuberculosis. There was a freezer labeled Ebola. It was like these silver Ziplocs inside and the CDC wouldn't test it, which is crazy.”
Afeyan: Early immune interventions may shield against flu, coronavirus, and HIV
“Because I think that we're learning enough about the immune system that if we intervene early enough and broadly enough, we may well create a shield, a protective shield against these hyper variable viruses like influenza, like Corona, like rhinovirus that cau…”
Strogatz: Math revealed HIV produces a billion virus particles daily
“By making measurements on the rate of this exponential drop Perelson and Ho were able to show that the body HIV was producing about a billion virus particles every day. HIV was making an enormous amount of new virus, and the immune system was clearing it out a…”
Strogatz: Mathematical modeling proved three-drug therapy suppresses long-term HIV mutations
“What Perilson's math showed is that if you did two drugs, your odds were a little better, because then the virus would have to do two simultaneous mutations. The odds of that were lower than one. But three drugs would be the sweet spot where The odds were so l…”
Church: Targeting HIV via CRISPR is more justifiable than Mendelian diseases
“Yeah, I think that we want an example of a disease that is very common, and most of the gene therapies are rare, whether they're editing or not, and we want something that's very serious, and certainly HIV falls in that category, So it struck me as a plausibly…”