Dopamine

topic on 6 shows · 18 statements across 12 episodes

the Knowledge Project BigDeal Lenny's Podcast My First Million WTF is with Nikhil Kamath the a16z Podcast

18 statements about Dopamine, every show

BIGDEAL Assertion Contradicted
Sanchez: Passive information consumption depletes dopamine needed for execution
“Neuroscience shows you're burning the exact dopamine your brain needs for execution. It can't tell the difference.”
Codie Sanchez May 25, 2026 ▶ 6:27 How to Rewire Your Brain to Hate Procrastination
BIGDEAL Assertion Contradicted
Sanchez: The Brain Only Releases Momentum Dopamine After Starting Action
“The brain only releases the dopamine of momentum once you move. The brain's like, you don't get this before you do the thing. So if you're waiting for the feeling to show up before you begin, that's biologically impossible.”
Codie Sanchez May 25, 2026 ▶ 8:38 How to Rewire Your Brain to Hate Procrastination
BIGDEAL Assertion Contradicted
Sanchez: Carnegie Mellon Study Finds Open-Ended Questions Trigger Dopamine
“Carnegie Mellon scientists discovered that when you ask someone a question, especially an open-ended one, their brain releases dopamine.”
Codie Sanchez Dec 22, 2025 ▶ 4:51 Stop Rambling: The 3-2-1 Speaking Trick That Makes You Sound Like A CEO
WTF Insight
Das: Capitalism Will Always Reward Products That Deliver Immediate Dopamine
“Capitalism, I think will always reward whatever hacks your brain to give you reward immediately in dopamine. And that means that's why there was shift to shorter video. It's an easier hack for the brain.”
Debargo "DD" Das Aug 29, 2025 ▶ 1:08:36 Inside Silicon Valley’s VC Playbook | WTF is Venture Capital? - 2025 Edition | Ep. 24 · Nikhil Kamath
BIGDEAL Assertion Supported
Dial: Cocaine raises dopamine levels by about 250%
“When you do when you do cocaine, usually your dopamine goes up by about 250%.”
Rob Dial Dec 18, 2024 ▶ 42:33 The Motivation Expert: Why You Are Stuck & Not Achieving Your Goals | Rob Dial
LENNY'S PODCAST Assertion Contradicted
Abrahams: Cursing releases neurochemicals that blunt cortisol and lower anxiety
“There's research that says that when you swear curse, it actually helps you reduce anxiety. When you curse, you release a flood of neurochemicals that blunt out the neurochemicals associated with anxiety, cortisol being a big one. So you get a big dopamine hit…”
Matt Abrahams Mar 31, 2024 ▶ 30:52 How to speak more confidently and persuasively | Matt Abrahams (professor, speaker, author)
Dr. Lembke: Dopamine Speed and Volume Dictate Addictiveness
“Dopamine is the most important neurotransmitter for the experience of pleasure, reward, and motivation. It's not the only neurotransmitter involved in that process, but it is the common pathway for all reinforcing substances and behaviors. Anything that's rein…”
Dr. Anna Lembke Feb 21, 2023 ▶ 3:28 Dr. Anna Lembke: Between Pleasure and Pain
Dr. Lembke: Dopamine Primarily Drives Motivation, Not Pleasure
“Well, it was originally thought that dopamine was primarily related to the experience of pleasure, euphoria, getting high, but a series of important experiments suggest that dopamine may be even more important for motivation, that is our willingness to do the …”
Dr. Anna Lembke Feb 21, 2023 ▶ 4:08 Dr. Anna Lembke: Between Pleasure and Pain
Dr. Lembke: Dopamine Deficits Drive Addiction Cravings More Than Highs
“The other thing is that that's very important here is that once people start to become addicted, what's salient is not so much the release of dopamine when they're getting high or experiencing pleasure, but it's actually the decrease in dopamine in between or …”
Dr. Anna Lembke Feb 21, 2023 ▶ 5:50 Dr. Anna Lembke: Between Pleasure and Pain
Dr. Lembke: Drug Anticipation Creates a Dopamine Deficit That Drives Craving
“There's also a little mini spike in dopamine when they see the light, so just anticipating the drug gets us a little bit high, but the really interesting thing is that right after that little increase in dopamine from the light, we actually go below baseline l…”
Dr. Anna Lembke Feb 21, 2023 ▶ 30:39 Dr. Anna Lembke: Between Pleasure and Pain
KNOWLEDGE PROJECT Assertion Partly supported
Huberman: Morning Light Triggers Real Cortisol, Adrenaline, and Dopamine Release
“That's not a placebo effect. That's a real effect of the release of cortisol and adrenaline into your body. The release of dopamine is controlled by light, powerful neuromodulator that makes you feel good.”
Dr. Andrew Huberman Mar 22, 2022 ▶ 17:58 Andrew Huberman: The Science of Small Changes
KNOWLEDGE PROJECT Assertion Supported
Huberman: Cold water exposure triggers a 2.5x sustained dopamine increase
“There's a paper published in the European Journal of Physiology. It showed that there's a 2.5 X huge increase in dopamine release, very long lasting. 2.5 X is the amount of dopamine that's triggered by the use of cocaine, but the difference is cocaine has a ve…”
Dr. Andrew Huberman Mar 22, 2022 ▶ 37:21 Andrew Huberman: The Science of Small Changes
KNOWLEDGE PROJECT Assertion Partly supported
Huberman: About 10% of people experience a dopamine surge from alcohol
“Now about 10% of people have a genetic predisposition to get a big dopamine increase from alcohol.”
Dr. Andrew Huberman Mar 22, 2022 ▶ 54:12 Andrew Huberman: The Science of Small Changes
MY FIRST MILLION Assertion Partly supported
Parr: Gratitude triggers dopamine release in prefrontal cortex to boost motivation
“Basically there's something about like the prefrontal cortex and how gratitude actually releases dopamine and it's proven to make you more motivated and happy.”
Sam Parr Nov 30, 2021 ▶ 8:31 Holiday Special: Great Finds (Products, Apps, Media)
MY FIRST MILLION Assertion Supported
Huberman: Published data shows Yoga Nidra upregulates dopamine in the brain
“There are some interesting data published showing that these Yoga Nidra Meditations, if you will, are can upregulate some of the neurotransmitters in the brain, including dopamine that make you prepared for action.”
Dr. Andrew Huberman Nov 18, 2021 ▶ 29:39 Dr. Andrew Huberman’s Path to Fame, Money, and Total Human Optimization
Puri: Modern human struggle shifted from resource scarcity to dopamine abundance
“The ancient struggle was scarcity. You know, the ancient struggle was we just didn't have enough. We didn't have enough food. We didn't have enough water. We didn't have enough you know, access to medicine, entertainment, whatever. And the modern struggle is a…”
Shaan Puri Oct 20, 2021 ▶ 11:45 Dopamine Fasts, Cruise Ship Investing, and Elon vs Bezos with Andrew Wilkinson, Co-Founder of Tiny
KNOWLEDGE PROJECT Assertion Supported
McGonigal: Concussions functionally impair future imagination and dopamine activation
“So there's actually a functional loss in your ability to imagine the future. And then when you do imagine the future, even if you're thinking about things that normally you get, would get you excited, your brain is basically refusing to fire up The pathways th…”
Jane McGonigal Jan 19, 2021 ▶ 9:19 #101 Jane McGonigal: The Psychology of Gaming
a16z Assertion Supported
Jeff Wu: Nootropics operate via three main biological pathways
“And broadly speaking, nootropics work in three sort of main pathways. One main pathway is sort of increasing the different neurotransmitters levels in your brain, and these can be sort of acetylcholine or dopamine, things that are associated with learning and …”
Jeff Woo Jan 2, 2019 ▶ 2:48 a16z Podcast | Nootropics and the Best Version of Your Brain, Yourself

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