Chronic Disease

topic on 6 shows · 10 statements across 9 episodes

American Optimist the Knowledge Project BigDeal How I Built This the a16z Podcast All-In

10 statements about Chronic Disease, every show

AMERICAN OPTIMIST Assertion Supported
Gebbia: 70% of Americans across all age groups have chronic disease
“You know, 70% of people have chronic disease. It's kind of insane. You know, at all, all age ranges. And it's like, we spend the most on healthcare, yet we have the most disease.”
Joe Gebbia Jan 20, 2026 ▶ 8:43 The Secret Team Fixing America's Broken Systems · Joe Lonsdale
ALL-IN Assertion Not checkable as stated
Makary: Insulin resistance is at the root of almost every chronic disease
“And it is at the root of almost every chronic disease, insulin resistance, general body inflammation,”
Dr. Marty Makary Jan 15, 2026 ▶ 40:20 Supercharging a New FDA: Marty Makary on Science, Power & Patients
ALL-IN Assertion Supported
Makary: 40% of American children have a chronic disease
“Well, first of all, we have failed with our food system. Look at the fact that 40% of American kids have a chronic disease.”
Dr. Marty Makary Jan 15, 2026 ▶ 42:21 Supercharging a New FDA: Marty Makary on Science, Power & Patients
BIGDEAL Assertion Supported
Saladino: US chronic health metrics worsen despite healthier self-reported habits
“We are being counseled by our government to eat healthy, and more people will respond to surveys saying they're eating healthy, more people will respond to surveys saying they're exercising, less people are smoking, but everything is going in the wrong directi…”
Paul Saladino Dec 11, 2024 ▶ 0:34 Everything I Learned In Med School Was WRONG | Paul Saladino
HOW I BUILT THIS Assertion Not checkable as stated
Lacy: Prenuvo scans detect chronic disease 10 to 20 years before symptoms
“I think one of the really fascinating things that we have discovered as we started to image more and more patients is we can see oftentimes at very early stages of chronic disease, 1020 years before you might ever feel symptoms.”
Andrew Lacy Dec 7, 2023 ▶ 27:40 Full body preventive health care with Andrew Lacy of Prenuvo
ALL-IN Assertion Partly supported
RFK Jr.: US chronic disease rate rose from 6% to 54% by 2006
“We went from having six percent of Americans affected by chronic disease to 54% by 2006.”
Robert F. Kennedy Jr. May 5, 2023 ▶ 59:17 In conversation with Robert F. Kennedy Jr.
HOW I BUILT THIS Prediction Not checkable as stated
Wastewater platforms will eventually track chronic diseases like cancer and diabetes
“I absolutely see the future where we will have enough data to start to learn kind of predictive components of data To then be able to look at those other more chronic diseases and ultimately, of course, be able to flag a new threat before anybody else knows ab…”
Mariana Matus Feb 9, 2023 ▶ 15:34 HIBT Lab! Biobot Analytics: Mariana Matus and Newsha Ghaeli
AMERICAN OPTIMIST Assertion Partly supported
Mackey: 80% of US Healthcare Spending Goes to Lifestyle-Related Chronic Diseases
“80% of what we spend on health care in America are for chronic diseases, Joe. Diseases that tie directly back into our diet and lifestyle.”
John Mackey Sep 15, 2021 ▶ 19:23 Whole Foods Co-Founder & CEO John Mackey: Conscious Capitalism and Repairing America's Division · Joe Lonsdale
a16z Opinion
Extending lifespan is the most powerful way to address chronic disease
“So I work on extending human lifespans because I believe this is the most powerful way to address chronic disease.”
Kristen Fortney Dec 23, 2018 ▶ 0:06 Extending Human Lifespan
Insulin Resistance Drives Major Chronic Diseases and Originates in Liver Fat
“Whatever causes insulin resistance causes obesity, diabetes, high blood pressure, heart disease, stroke, cancer, Alzheimer's, virtually every chronic disease has a link to insulin resistance, and the best research on what causes insulin resistance suggests tha…”
Gary Taubes Nov 30, 2017 ▶ 25:42 #25 Gary Taubes: Is Sugar Slowly Killing Us

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