psilocybin
6 statements across 3 episodes · 6 bullish · 0 bearish · 3 people on the record · first statement Oct 7, 2022 by Jason Calacanis · across every show →
Everything said about psilocybin, oldest first
Oct 7, 2022 positive
Jun 19, 2025 positive
Mar 26, 2026 positive
Bryan Johnson: Kernel scans show psilocybin generated new neural connectivity
“So you look at my brain on psilocybin from Kernel, you see my patterns before, like the New York to London connection. You see my brain afterwards, and it's exactly what you said. New patterns are emergent. The old ones have quieted down. It's like a new map o…”
Mar 26, 2026 positive
Mar 26, 2026 positive
Bryan Johnson says psilocybin triggered a metabolic reset and microbiome shift
“What we found in psilocybin though, is it had, we found a first in human observation. It had this metabolic reset in the brain where my blood glucose before this was in the top. 99.5 percentile of all the population. Okay. After it went to the top 99.9 percent…”
Mar 26, 2026 bullish
Bryan Johnson: 5-MeO-DMT annihilates the default mode network compared to psilocybin
“Five MEO DMT compared to psilocybin, like just absolutely like blasted clean. My default mode network. It felt like psilocybin dampens it, like it softens it, but this thing just annihilated my default mode network.”