epigenome

2 statements across 2 episodes · 0 bullish · 0 bearish · 2 people on the record · first statement Oct 1, 2024 by Juan Carlos Izpisua Belmonte · across every show →

Everything said about epigenome, oldest first

Oct 1, 2024
Assertion Partly supported
Belmonte: Closed chromatin maintains cell youth while open chromatin causes aging
“When the epigenome, when the chromatin is closed, we call this heterochromatin, the cell is young, is healthy. When the chromatin is open, it leads to the increase, the loss of buffer capacity, and therefore, disease and aging.”
Juan Carlos Izpisua Belmonte Oct 1, 2024 ▶ 9:39 Juan Carlos Izpisua Belmonte, Altos Labs | All-In Summit 2024
Nov 23, 2024
Assertion Supported
Friedberg: Study shows fat cells retain epigenetic memory after weight loss
“In humans, they basically took five individuals that were obese and lost more than 25% BMI. And they looked at the epigenome, they looked at the markers of what genes are upregulated and downregulated before and after they lost the weight. After they lost the …”
David Friedberg Nov 23, 2024 ▶ 1:02:45 DOGE unveils a roadmap, Unlocking GDP Growth, WW3 escalation, Fat cell memory
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