AlphaFold, every mention
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every year anyone David Friedberg 33Jason Calacanis 16Chamath Palihapitiya 15Demis Hassabis 6Sundar Pichai 1Sergey Brin 1
Verbatim, from the transcripts: the passages where AlphaFold comes up
Can the AI Industry Regulate Itself? Stripe Wants PayPal, China Catches Up, NY Bans Datacenters
- ▶ 1:25:49 David Friedberg And they started with AlphaFold, and they used AlphaFold to find a protein that could bind to CML and activate an enzymatic or process that would break it down. 4 times in the scene
Inside Google DeepMind: AGI, Robotics, & World Models Explained - Demis Hassabis
- ▶ 0:58 unnamed speaker For the incredible breakthrough of AlphaFold, maybe you may have done this before, but I know everyone here would love to hear your recounting of how you, where you were when you won the Nobel Prize. 2 times in the scene
- ▶ 15:32 Demis Hassabis And I think we've been showing at DeepMind a lot of the way of that, obviously AlphaFold, uh, most famously, but actually we've, we've, um, applied
- ▶ 24:54 Demis Hassabis So, so I also run isomorphic, which is our spin out company, uh, to revolutionize drug discovery, building on our alpha fold breakthrough in, in protein folding. 2 times in the scene
- ▶ 26:53 Demis Hassabis So AlphaFold itself is a hybrid model where you have the learning component, this probabilistic component you're talking about, which is, you know, based on neural networks and transformers and things, and that's learning from the data you… 3 times in the scene
Sundar Pichai, CEO of Alphabet | The All-In Interview
- ▶ 59:08 Sundar Pichai I, the founders, think about it as, like, the underlying innovation by which, so we think of the units of quantum, right, you know, alpha fold and hence isomorphic, right, you know, self-driving and building the Waymo driver, and hence all…
Hurricane fallout, AlphaFold, Google breakup, Trump surge, VC giveback, TikTok survey
- ▶ 29:04 Jason Calacanis AlphaFold creators just won a Nobel Prize in Chemistry. 3 times in the scene
- ▶ 32:50 David Friedberg And, and by the way, since, since then, they've come out with AlphaFold III.
Sergey Brin | All-In Summit 2024
- ▶ 10:53 Sergey Brin Well, I would say in biology, you know, we've had AlphaFold for quite a while, um, and I'm not personally a biologist, but when I talk to biologists out there, like, everybody uses it, and it's more recent, uh, variants, um, and that is, I…
Sam Altman: Getting Fired (and Re-Hired) by OpenAI, Agents, AI Copyright issues
- ▶ 26:47 Chamath Palihapitiya But Alpha-IV, yeah.
- ▶ 30:52 David Friedberg So these models that are predicting protein structure, like, let's say, right, this is the whole basis, and now, now other molecules at alpha fold three, can they, can, yeah,
- ▶ 1:09:50 David Friedberg After the break, I think we should talk about AlphaFold three.
- ▶ 1:29:44 Jason Calacanis Friedberg about this, ah, alpha fold, this folding proteins.
- ▶ 1:30:20 David Friedberg The topic a couple of weeks ago, but I will say that alpha fold three that was just announced today and demonstrated by Google, um, is a real, uh, I would say breathtaking moment, um, for biology, for bioengineering, for human health, for… 3 times in the scene
- ▶ 1:30:39 David Friedberg Um, you remember when they introduced alpha fold, alpha fold two, we talked about DNA codes for proteins. 2 times in the scene
- ▶ 1:30:39 David Friedberg Um, you remember when they introduced alpha fold, alpha fold two, we talked about DNA codes for proteins.
- ▶ 1:36:08 David Friedberg So with this system, one of the things that this alpha fold three can do is predict what molecules will bind and promote certain sequences of DNA, which is exactly what we try and do with the Yamanaka factor based expression systems and…
E143: Nvidia smashes earnings, Arm walks the plank, M&A market, Vivek dominates GOP debate & more
- ▶ 22:43 Chamath Palihapitiya You combine it with something like alpha fold, and you can understand protein folding, and all of a sudden you can sequentially start to put tools together that could theoretically give you much higher probability guessing for specific…
E112: Is Davos a grift? Plus: globalist mishaps, debt ceilings, TikTok's endgame & more
- ▶ 1:19:24 David Friedberg And rather than just doing testing in software, you can actually use tools like AlphaFold that can be predictive of large molecules
E111: Microsoft to invest $10B in OpenAI, generative AI hype, America's over-classification problem
- ▶ 40:53 David Friedberg We've seen Google share alpha fold and share a number of predictive models and toolkits and make them publicly available and put them in Google's cloud. 2 times in the scene
E109: 2022 Bestie Awards Live from Twitter HQ
- ▶ 2:02:25 Chamath Palihapitiya AlphaFold three, which basically has almost near perfect accuracy in protein folding.
E106: SBF's media strategy, FTX culpability, ChatGPT, SaaS slowdown & more
- ▶ 1:19:08 David Friedberg Um, alpha fold and so on, and they've been public about that, but a lot of that is really to generate interest and hype in what's next.
- ▶ 1:30:43 Jason Calacanis Then you got images, then you got chat, maybe you have proteins going on with the alpha fold stuff.
E103: Tech layoffs surge, big tech freezes hiring, optimizing for profits, election preview & more
- ▶ 1:17:52 David Friedberg And so remember AlphaFold made this big announcement that they had highly, um, accurate predictions of protein structure, the three dimensional shape of proteins. 5 times in the scene
E102: Elon closes Twitter deal, $META uncertainty, Zuck's historic bet, big tech decline & more
- ▶ 1:29:51 David Friedberg And because of the ability now to do DNA sequencing, and now with, um, uh, you know, some of the alpha fold technology, we can actually take the genome from that bacteria, predict
E94: NFT volume plummets, California's overreach, FBI meddling, climate change & national security
- ▶ 39:38 Chamath Palihapitiya And they're just going to use alpha fold, you know, and what it's really going to do is potentially put a bunch of research scientists out of work. 2 times in the scene
E85: SBF's crypto bailout, Zendesk sells for ~$10B, buyout targets, US diplomacy, AlphaFold & more
- ▶ 1:28:33 Jason Calacanis Really quick, tell us what's going on in AlphaFold world, Sultan of Science.
E51: Supply Chain Shortages, Inflation, DeSantis, Ted Sarandos Netflix Memo, Cancel Culture, Fan Q&A
- ▶ 1:23:38 Jason Calacanis He says, Alphaphone made great progress in predictive protein folding.
E41: Vaccine policy, Big Tech, DeepMind's latest breakthrough, wealth creation, opportunity & more
- ▶ 45:51 David Friedberg So this morning, you know, DeepMind, which published AlphaFold, we talked about this a few episodes ago. 3 times in the scene
- ▶ 56:55 Chamath Palihapitiya So back to the thing that Friedberg brought up before, I think alpha fold is incredible.
- ▶ 58:50 Jason Calacanis I thought we just went over the alpha fold stuff way too fast. 4 times in the scene
E26: State of Venture Capital, plus fan questions on longevity, decentralization & quantum computing
- ▶ 29:00 Chamath Palihapitiya This is why alpha fold beat quantum computers to the solution of protein folding.
E15: “The Besties” All-In’s inaugural award show covering the best, worst & most memorable of 2020
- ▶ 39:38 David Friedberg I'm gonna say AlphaFold, you know, that we talked about in the last podcast, I think, um, AlphaFold feels to me like what ARPANET was, which was the origins of the internet, you know, uh, back when it was first installed, and no one really 3 times in the scene
E14: Salesforce acquires Slack, DeepMind’s AlphaFold breakthrough, Trust Fund Socialists & more
- ▶ 25:40 Jason Calacanis Let's move to AlphaFold. 5 times in the scene
- ▶ 27:26 Chamath Palihapitiya Freeberg, explain AlphaFold, please. 3 times in the scene
- ▶ 34:32 Chamath Palihapitiya Um, and so the, the, just think about this, like, this is where, like, you gotta, you gotta love companies like Google, the fact that they exist, because from, you know, page rank in 1999 to CPC ads in 2003 and four, um, we have alpha fold… 4 times in the scene
- ▶ 1:07:37 Chamath Palihapitiya And the reality is like, you know, we just talked about alpha fold.
- ▶ 1:24:36 David Friedberg AlphaFold, I think, is the realization of one of the greatest capitalist enterprises in history, if not the greatest, you know, alphabet. 3 times in the scene