Chai 2
product on 2 shows · 6 statements across 2 episodes · said 46 times in 2 episodes since 2025
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6 statements about Chai 2, every show
McPartlon: Chai-2 generated binders for 25 targets with 20% hit rate
“So we designed antibodies to 50 targets for that paper, got binders to about half of them with being on average around a 20% hit rate for binding.”
McPartlon: Chai-2 achieved 0.33 angstrom error in cryo-EM testing
“And in this case, it was a 0.33 angstrom error, which is one third the width of an atom.”
McPartlon: Chai-2 was evaluated on targets with no known antibody binders
“We actually chose these targets specifically like to have no known antibody binder. So like if we did get a hit, like it was definitely the first antibody hit to this target.”
Dent: Chai-2 hits nearly 20% wet-lab antibody binding success
“We have about a two week validation cycle in the lab, and two weeks later, we see that roughly close to 20% of these antibodies actually bind their targets in the intended way.”
Meier: Chai-2 maintains success rate on targets with 25% sequence similarity
“We actually even have a slide in our paper in the supplement where we actually look at an even harder subset. So not looking at things that are, you know, up to a sequence similarity with the model, but actually pushing all the way down to 25%. So really looki…”