Chai-2

3 statements across 1 episodes · 2 bullish · 0 bearish · 1 people on the record · first statement Aug 11, 2026 by Matt McPartlon · said 28 times in 1 episodes since 2026 · across every show →

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brought up most by RJ Haneke (9), Neil Patil (8), Matt McPartlon (7)

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2026 28 mentions in 1 episode

🔬They Thought the Model Was Broken — Matt McPartlon & Neil Patil, Chai Discovery Aug 11, 2026 · 28 mentions · from 3:13
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Everything said about Chai-2, oldest first

Aug 11, 2026

Disclosure

McPartlon: Chai-2 was evaluated on targets with no known antibody binders

“We actually chose these targets specifically like to have no known antibody binder. So like if we did get a hit, like it was definitely the first antibody hit to this target.”

Matt McPartlon Aug 11, 2026 ▶ 35:01 🔬They Thought the Model Was Broken — Matt McPartlon & Neil Patil, Chai Discovery

Aug 11, 2026 positive

Assertion Supported

McPartlon: Chai-2 generated binders for 25 targets with 20% hit rate

“So we designed antibodies to 50 targets for that paper, got binders to about half of them with being on average around a 20% hit rate for binding.”

Matt McPartlon Aug 11, 2026 ▶ 22:51 🔬They Thought the Model Was Broken — Matt McPartlon & Neil Patil, Chai Discovery

Aug 11, 2026 positive

Assertion Supported

McPartlon: Chai-2 achieved 0.33 angstrom error in cryo-EM testing

“And in this case, it was a 0.33 angstrom error, which is one third the width of an atom.”

Matt McPartlon Aug 11, 2026 ▶ 34:45 🔬They Thought the Model Was Broken — Matt McPartlon & Neil Patil, Chai Discovery

Chai-2

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Everything said about Chai-2, oldest first

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