science

“And I think it's totally possible that these open journals get to a point where they have you know, a reputation like science or nature. As long as you convince people to, you know, publish their papers on these journals, it's, there's nothing about science or…”

“The system nowadays, it's, does not seem to be perfect for the way things work nowadays, and we would love to see either via format or some other platform to try to tackle that, and try to do something to make the peer review a better system, or to change it s…”

“It's probably the way to get these open, open journals to be as popular as nature or science is to convince Really, people that already have a tenure are really famous scientists to publish on those journals. You already have your position. You already have yo…”

“As far as I know, our clinical trial was the first time ever that form vision had been, like, had created, like, a coherent image in the mind's eye of a person.”

“One of the nice things about our device is that it doesn't We're somewhat agnostic to the reason that you lost the photoreceptors, and so we think it'll also work for retinitis pigmentosa, for Stargardt's, for these other indications.”

“What we were able to do were find optogenetic proteins that are so sensitive that they're sensitive to like indoor office lighting”

“And with our retinal prosthesis that we, what we saw in the trial was we can take a patient who's been unable to see faces for a decade and allow them to read every letter on an eye chart.”

“The qualia of Prima is, is normal sight. It's black and white. It's only a, it's a small field of view, but it's vision.”

“So we there's, it's one cell line and the, probably the single deepest area of IP on this is that we've hidden them from the immune system. So we're one of a really small number of companies that have, I think like pretty convincing, what we call hypoimmunogen…”

“And then we could target them to the bipolar cells, but that still has like five to seven years of clinical translation away if it ends up working, and there's a bunch of Pitfalls it could run into along the way”

“There's a big clinical trial in Europe across 17 sites, and there's a huge effect.”

“We're actually just about to start a new clinical trial on, on inherited retinal disease which affects much younger people.”

“But it comes with the potential of growing throughout the brain, forming biological connections all over the place. And I mean, that's what we've seen in, in the animal models. That's not in humans yet”

“I mean, I do think that you can get to close to native acuity, so kind of like your normal twenty-twenty vision. We're definitely not there yet, but I see a path to get there and be able to get Color and fill in a lot of the field of view. To be clear that it'…”

“It was an empirical discovery of our study that if you excite the bipolar cells with an image, you get an image in the mind's eye, because that is clearly the critical processing step in the retina that you wanted to preserve.”

“We finished a big clinical trial last year, which was published in the New England Journal of Medicine in the fall.”

“So we are submitting for approval now. It's not approved on, on the market yet. Hope to have that later this year.”

“Science is not about curve fitting. Science is about finding the equation, finding the most compressive symbolic model of your pile of observation.”