AlphaFold, every mention
23 scenes, the whole family · ← back to AlphaFold
tap a year for its mentions
every year anyone John Jumper 20Demis Hassabis 11Garry Tan 5Jeff Dean 1Diana Hu 1
Verbatim, from the transcripts: the passages where AlphaFold comes up
Jeff Dean: The 1% Rule for Building in AI · Y Combinator
- ▶ 30:31 Jeff Dean Yeah, I mean, I think, like, if you look at, ah, my colleague's work on, say, alpha fold, that was a very specific model for, ah, protein folding, and it was highly successful.
- ▶ 31:20 Diana Hu So if some of you find a problem that's similar shape like alpha fold could be a good problem to work on.
Demis Hassabis: Agents, AGI & The Next Big Scientific Breakthrough · Y Combinator
- ▶ 1:20 Garry Tan AlphaFold cracked protein structure prediction, a 50 year grand challenge in biology, and they gave it away for free to every scientist on Earth.
- ▶ 18:38 Demis Hassabis What I often say about that is, like, if we look at the things we've done, like AlphaGo, so obviously, very famously, you'll all know about the move-thirty-seven in game two, and for me, I was waiting for a moment like that to start the… 2 times in the scene
- ▶ 20:43 Demis Hassabis We're huge proponents of, in general, of open source and open science, and you mentioned AlphaFold at the beginning, you know, we put that all out there for free, and all of our science work, even still today, we publish in, you know, the…
- ▶ 25:27 Garry Tan AlphaFold III took us beyond proteins to a broad spectrum of biomolecules.
- ▶ 25:39 Demis Hassabis Well, at isomorphic labs, which we spun out from, from, from, from DeepMind after we did AlphaFold II,
- ▶ 25:48 Demis Hassabis It's, it's, it's trying to build out, uh, not just alpha fold.
- ▶ 29:24 Demis Hassabis And alpha fold is the prototypical example of what we want to do. 3 times in the scene
- ▶ 29:59 Demis Hassabis And the ones you mentioned, I think we're almost like an alpha fold one moment.
- ▶ 33:24 Garry Tan So, I mean, AlphaFold was like an example of a spike that you pursued and it worked, you know, what makes the scientific domain ripe for an AlphaFold style breakthrough? 2 times in the scene
- ▶ 35:14 Garry Tan I guess to get a little meta, I mean, we were talking about humans using these methods to create AlphaFold, but then there's a meta level, which is humans using AI to explore the space of possible hypotheses.
- ▶ 39:47 Demis Hassabis And it goes a little bit back to what you said earlier about alpha fold and general AI systems. 2 times in the scene
Nobel Laureate John Jumper: AI is Revolutionizing Scientific Discovery · Y Combinator
- ▶ 3:54 John Jumper That, ultimately, we are building tools that will enable scientists to make discoveries, and what I think is really heartening about the work we've done and the part that really, I think, still just resonates with me at my core is there…
- ▶ 10:51 John Jumper We want to put something in the middle and then alpha fold, and we want to end up with something on the right.
- ▶ 13:29 John Jumper So someone, AlphaFold II is the system that is quite famous, the one that, ah, was quite a large improvement. 3 times in the scene
- ▶ 13:34 John Jumper AlphaFold I was the best in the world. 2 times in the scene
- ▶ 15:27 John Jumper Alpha-fold is an equivariant system, and it's great. 2 times in the scene
- ▶ 15:48 John Jumper Alpha fold itself on this GDT scale that you can see on the left graph, alpha fold two was about 30 GDT better than alpha fold one, and equivariance explains two or three of this.
- ▶ 15:48 John Jumper Alpha fold itself on this GDT scale that you can see on the left graph, alpha fold two was about 30 GDT better than alpha fold one, and equivariance explains two or three of this.
- ▶ 20:09 John Jumper You know, this morning I got an alpha fold prediction, and now it's much better. 2 times in the scene
- ▶ 20:48 John Jumper In fact, there was a special issue of science on the nuclear pore complex a few months after the tool came out, and the special issue was all about this particular very large kind of several hundred protein system, and three out of the… 6 times in the scene
- ▶ 26:42 John Jumper And I think this is really where we see the foundational model aspect of alpha fold or other narrow systems.