AlphaFold

“There about, I think, 35,000 citations of AlphaFold, but within that is there are tens of thousands of examples of people using our tools to do science that I couldn't do on my own.”

“The tweet on the left from Yoshitaka Morawaki came out two days after our code was available. We had predicted the structure of individual proteins, but we considered, we were working on building a system that would predict how proteins came together. But, ah,…”

“I like to think that our work Made the whole field of what's called structural biology, biology that deals with structures, you know, five or 10% faster. But the amount to which that matters for the world is enormous.”

“One is that we open source the code and we actually open source the code about a week before we released a database of predictions starting originally at 300,000 predictions and later going to two hundred million. Essentially every protein from an organism who…”

“I think we will start to see this on more general systems, be them LLMs or others, That we will find more and more scientific knowledge within them, and we'll use them for important, important purposes, and I think this is really where this is going, and I thi…”

“And we had about a third of the error of any other group on this assessment.”

“It isn't about one idea. It's about many mid-scale ideas that add up to a transformative system, and it's very, very important when you're building these systems to think about what we would call in this context biological relevance.”

“I was told by some of my, you know, pharma executive friends that, you know, almost every drug Discovered from now on will have used alpha fold at some point in it, in the drug discovery process.”

“The lesson I've learned from all the alpha projects we've done, specifically alpha go and alpha fold is I think the techniques we have and the problems I look like to look for are great in, if this, if the situation can be described as massive combinatorial se…”

“One thing I can think see happening is Gemini, Claude, or one of these general systems making use of alpha fold, like specialized systems as tools. I don't think we're going to have it just in one giant brain because it will have too much regression in if I pu…”