Hassabis: AlphaFold is a hybrid model incorporating physics and chemistry rules
Demis Hassabis · Inside Google DeepMind: AGI, Robotics, & World Models Explained - Demis Hassabis · Sep 12, 2025 · at 26:53
Demis Hassabis, CEO of Google DeepMind, explains the underlying architecture of DeepMind's AlphaFold model.
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“So AlphaFold itself is a hybrid model where you have the learning component, this probabilistic component you're talking about, which is, you know, based on neural networks and transformers and things, and that's learning from the data you give it you know, any data you have available, but also to have, in a lot of cases with biology and chemistry, there isn't enough data to learn from. So you also have to build in some of the rules about chemistry and physics that you already know about.”
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