Everything Vijay Pande said on any show that made the record, most notable first. Each card names its show and opens the statement there.
Pande: Cancer could easily not exist in 10 years
“Cancer could easily just not exist in 10 years, and that's due to this change in how we think about things, and there's all these things on the back end.”
Vijay Pande: Compute costs will fall a million-fold over 20 years
“The nice thing about the exponentials is that, you know, things will go down a factor of a thousand, like, every 10 years on the Moore's Law side, and we'll continue to see that. So, a thousand, maybe in 20 years, a million, you know, a thousand times a thousa…”
Pande: Healthcare AI needs a 10x improvement threshold to overcome stigma
“Yeah, so I think the bar is different. This might be the magic has to get to 10 X. Mm-hmm. Something where 10% is probably within noise and without doubt or something like that, but 10 X is kind of the thing where, like, okay, okay. We have to think of things …”
Pande: Healthcare service providers will eventually transition into AI companies
“Well, you can imagine a services company that's providing some sort of healthcare service. It's training AI with its workers. And then the easy things, which are probably the boring things anyways, AI starts to do. And then the more interesting, complicated th…”
Pande: FDA rejects new drugs that are cheaper but equal in efficacy
“If you had a drug that was as good as the best drug, but cheaper, That still can't get that won't go by the FDA because they actually has to be better than the last drug, even if it's not better scientifically, but it's better in other ways.”
Pande: The world's largest company will be in consumer health tech
“The biggest company in the world will be a consumer health tech company.”
Pande: AI is turning scientific discovery into an industrialized process
“Today, what I want to talk about is how AI is industrializing discovery.”
Pande: AI biomarkers achieve 90% accuracy compared to 50% for PSA tests
“Like a PSA test is roughly 50% accurate. These new AI discovered biomarkers are considerably more accurate, you know, with sensitivity and specificities in the nineties.”
Pande: Animal models will become machine learning inputs, not pass/fail tests
“We're not going to think about these models as some sacrosanct up or down vote. That they are basically going to be features into machine learning where you're going to have this as the inputs and label data in humans from previous experiments to be able to co…”
Pande: Machine learning will cut protein therapeutic costs by up to 90%
“If you could use machine learning methods to decrease the cost, and there's a lot of reason to think the cost could go down by half or a fifth or even a 10th, that would have a huge impact on drugs, as well as all the different proteins that are used in the bi…”
Pande: Real-world evidence will surpass clinical trials in utility
“And what I think we'll start to see is, especially as new statistical methods come online, that real world evidence will be very useful, in some ways will be more useful than what you can do in a clinical trial, both due to power and due to the fact of real li…”
Pande: Many students attend graduate school out of low risk tolerance
“A lot of people go to grad school because they're actually Not very risk tolerant. You know, that grad school is a comfortable thing to do.”
Pande: A dual-skilled generalist outperforms separate bio and CS experts
“And maybe I would just add, you know, what happens if you don't have this, and you try to substitute this with an A-plus computer scientist joined with another person who's an A-plus biologist. The problem there is they just do not know what the other one does…”
Pandey: Pharma companies will reframe themselves as data science companies
“Pharma companies will start to view themselves more as data generating companies and data science companies.”
Pandey: The future physical world will be engineered biology, not steel
“The future will not be steel and metal. It will be this sort of engineered biological thing that just grows, that has this function.”
Pande: AI early detection could be the missing link to curing cancer
“This is where AI could really be a part of the key missing link towards the cure to cancer.”
Pande: Genomic diagnostics scale across cancer types via repeatable engineering
“Science is something that you can't schedule creativity or the ability to come through a breakthrough. So if you have understood the science of colorectal cancer, what you've learned about a stool test probably is not going to be very useful for a breast cance…”
Pande: Data network effects never go off patent like biotech drugs
“Data network effects never go off patent. They just get stronger and stronger and help companies grow even after, even decades after.”
Pande: Biological engineering requires predictive accuracy, not 100,000 empirical guesses
“It's all about, can you make predictions? So if you think you can engineer something, you should be able to make 10 predictions and have three work, not making a 100,000 guesses and seeing what pans out.”
Pandey: Quantum computers will suddenly surpass classical computing at a specific threshold
“What will happen is a quantum computer at first will seem like it won't be all that useful. It will be below the number of qubits that you need. Maybe you need a hundred qubits to solve the problem and the existing machine only has 64. And so a classical compu…”
Pandey: Quantum computers do not need 100,000 qubits to deliver useful chemistry simulations
“Or enzymes. It's all the chemistry, you know, so, so this is something where a quantum computer could be able to do calculations that are either much bigger at much higher accuracy where actually would be essentially much bigger at higher, much much higher acc…”
Pande: Software will prove far more effective than small molecules for behavior
“I can imagine 10 years from now people would be like, well, what'd you expect? I mean, you wouldn't expect this small molecule that we didn't have like this Sense for how all of the human brain works and understanding behavior from a fomental molecular biologi…”
Pande: Digital therapeutics data moats outperform traditional pharmaceutical patents
“And you have an interesting barrier to entry that is far superior than something like patents.”
Pande: AI will accelerate doctors long before replacing them
“And I think before we talk about replacing doctors at all, that doesn't make any sense when we could be accelerating them. Exactly. And having them do so much more. And I, I'm pretty sure we'll see that first. Just like you don't think a word processor with a …”