Assertion Supported AI assessment confidence: 95% certainty 4/5 debate potential 1/5

Biohub predicted 3D structures for 1.1 billion proteins from global sequence databases

Alex Rives · 🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub · May 27, 2026 · at 7:41

Alex Rives explains the scale of the structural atlas built using the ESM-Cambrian foundation model at Chan Zuckerberg Biohub.

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“So we put together kind of all the world's largest protein sequence databases. And so that kind of amounts to 6.8 billion non-redundant proteins, and then we've resolved predicted structures for 1.1 billion of those, and we've also computed features across all of those so that we can make these linkages basically all across evolution and protein biology.”

quote is from the automated transcript, cleaned for reading: filler sounds and stutters are removed, nothing is rephrased. names can be misheard (the analysis reads context, assessments check outside sources). how →

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