Chan Zuckerberg Biohub

includes Chan Zuckerberg Biohub New York

12 statements across 2 episodes · 6 bullish · 1 bearish · 3 people on the record · first statement Nov 6, 2025 by Priscilla Chan · said 24 times in 2 episodes since 2025 · across every show →

Mentions by year, the whole family

brought up most by Mark Zuckerberg (3), Alex Rives (3), RJ Haneke (1), Priscilla Chan (1)

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Everything said about Chan Zuckerberg Biohub, oldest first

Nov 6, 2025
Disclosure
Chan: CZ Biohub NY engineers immune cells to detect heart plaques
“And our New York biohub, we're doing cellular engineering to say like, Hey, can you go in to this person's heart? Check if they have plaques that are causing problems, read it into your DNA, self lice, And then we can read out the signal as cell-free DNA and g…”
Priscilla Chan Nov 6, 2025 ▶ 47:00 Priscilla Chan and Mark Zuckerberg: Frontier AI + Virtual Biology To Solve All Diseases
Nov 6, 2025 positive
Disclosure
Zuckerberg: EvolutionaryScale team joins Biohub under Alex Rives
“We're doing that by basically combining the team that we have, that's already put out all the models that we're talking about today, plus having the evolutionary scale team, which is just like very renowned join. And Alex is basically going to be running the p…”
Mark Zuckerberg Nov 6, 2025 ▶ 29:13 Priscilla Chan and Mark Zuckerberg: Frontier AI + Virtual Biology To Solve All Diseases
Nov 6, 2025 neutral
Assertion Not checkable as stated
Zuckerberg: Biohub was probably first to build large-scale biology compute cluster
“I think we were probably the first to build out a large scale compute cluster for biological research.”
Mark Zuckerberg Nov 6, 2025 ▶ 30:03 Priscilla Chan and Mark Zuckerberg: Frontier AI + Virtual Biology To Solve All Diseases
May 27, 2026 positive
Prediction Not checkable as stated
Rives: Existing Tech Can Scale Biological Data 10x–100x Before Hitting Limits
“I think with current technology, you know, we can definitely kind of get, get data, 10 X to a hundred X where it is today with like relatively reasonable investments, you know, but then to get another 10 X or more in there, that's going to require, require a l…”
Alex Rives May 27, 2026 ▶ 1:03:19 🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
May 27, 2026 positive
Assertion Supported
Biohub predicted 3D structures for 1.1 billion proteins from global sequence databases
“So we put together kind of all the world's largest protein sequence databases. And so that kind of amounts to 6.8 billion non-redundant proteins, and then we've resolved predicted structures for 1.1 billion of those, and we've also computed features across all…”
Alex Rives May 27, 2026 ▶ 7:41 🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
May 27, 2026 bullish
Insight
Rives: Curing disease requires personalized computational models, not conventional pills
“What is, you know, what is the cure to disease look like, right? It's not a pill, right? It's not a medicine in the conventional sense. You know, it's going to have to be a system that is capable of modeling and understanding, you know, the underlying physiolo…”
Alex Rives May 27, 2026 ▶ 44:42 🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
May 27, 2026 negative
Opinion
Rives: Current Virtual Cell Models Cannot Predict Novel Interventions
“I think with, you know, kind of the current generation of models that are being called virtual cells, they are good representations of the underlying data, but, you know, they have a very limited ability to predict what will happen when you make a novel interv…”
Alex Rives May 27, 2026 ▶ 49:16 🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
May 27, 2026 bullish
Assertion Supported
Rives: ESMC Has Been Used to Successfully Design scFv Antibodies
“We've been able to use this to actually now go and design many protein binders, but I think sort of most excitingly, we've been able to use this to actually design antibodies, SCFVs, and we're seeing really, I think, exciting success rates and a small number o…”
Alex Rives May 27, 2026 ▶ 28:26 🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
May 27, 2026
Assertion Supported
Rives: The ESMC family includes 300M, 600M, and 6B parameter models
“So there's actually three models in that family. There's a three hundred million parameter model, a six hundred million. Parameter model and a six billion parameter model.”
Alex Rives May 27, 2026 ▶ 10:31 🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
May 27, 2026 bullish
Disclosure
CZ Biohub commits $500M to scale biological data creation and technology development
“We announced a few weeks ago, the virtual biology initiative we basically said, you know, we're gonna invest four hundred million internally in data creation and development of technology to scale data generation to be able to increase the number of modalities…”
Alex Rives May 27, 2026 ▶ 57:03 🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
May 27, 2026
Disclosure
CZ Biohub is open-sourcing the ESMC protein foundation model under MIT license
“At the time that this podcast comes out, we will have announced ESMC and this world model for protein biology. It's gonna be open source. It's gonna be MIT licensed, and we want people to use it.”
Alex Rives May 27, 2026 ▶ 1:09:10 🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
May 27, 2026
Disclosure
Biohub is building high-contrast cryo-electron tomography for atomic cell imaging
“At Biohub, I mean, the other thing that we're thinking about is can we actually experimentally resolve this? And so one of the things that we are building is cryo-electron tomography, and we're really building systems that can greatly increase the contrast Whe…”
Alex Rives May 27, 2026 ▶ 36:45 🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub
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