AI cell simulations will enable parallel reasoning across millions of biological hypotheses
Alex Rives · 🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub · May 27, 2026 · at 39:49
Alex Rives outlines the multi-scale paradigm shift from single-protein models to virtual cell models and digital reasoning in biology.
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“We're gonna have increasingly capable and accurate digital representations of molecules, genomes, cells, ultimately physiology. That's where you want to get. We're gonna have to go up that, that complexity scale, the levels of biological complexity that requires traversing a data barrier. There's, I think, data that, that does not exist that needs to be generated to achieve that level of predictive fidelity. And then we're going to have reasoning. And I think, you know, what that will mean is that we can reason over Thousands, millions, hundreds of millions of scientific hypotheses in parallel digitally using predictive oracles, which can, you know, actually predict the outcome of an experiment.”
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