Dec 11, 2024 · 1h 20m · bigdeal
Everything I Learned In Med School Was WRONG | Paul Saladino
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gold bands on the timeline = statements, start to end. Hover to read, click to jump. CC turns on captions
In this in-depth interview, Dr. Paul Saladino joins Codie Sanchez to challenge conventional medical guidelines, exposing the hidden dangers of ultra-processed foods, industrial seed oils, and environmental toxins while advocating for an ancestral animal-based lifestyle to restore metabolic and systemic health.
How this conversation actually went
Every chapter scored 0–10 on four independent dynamics. Hover any point for the reasoning behind the score. Codie holds 22.1% of the talking time here. How this is scored →
Codie as informed peer 3.1 Guest teaching 6.6 Guest disagreement 4.0 Codie pushing back 2.1
speaking balance: gold is Codie, purple is the guest (3 minute bins)
Sharpest disagreement ▶ 54:20 Doritos compared to cigarettes and warning labels
Paul forcefully pushes back against mainstream nutritionists who criticized his cigarette analogies, insisting that ultra-processed snack foods warrant explicit toxicity warnings.
Hardest push from Codie ▶ 0:52 Pushback on the calories-in calories-out modelCodie directly challenges Paul with the conventional thermodynamic argument that obesity stems strictly from caloric overconsumption rather than food processing.
Biggest teaching moment ▶ 6:20 Canola oil processing and hexane solvent extractionPaul breaks down the chemical engineering behind commercial seed oils, including hexane bleaching and deodorization at 500 degrees Fahrenheit.
Codie holds their own ▶ 28:15 Codie cites industry data on pre-teen cosmetic consumptionCodie demonstrates sharp domain knowledge by citing specific demographic growth metrics showing sub-sixteen girls driving skincare product sales.
the scores for every segment, with the reasoning behind each
| Chapter | Topic | Codie as informed peer | Guest teaching | Guest disagreement | Codie pushing back | Why |
|---|---|---|---|---|---|---|
| Processed Food Crisis and Chronic Illness Epidemic | 3 | 6 | 4 | 4 | Codie challenges the guest by presenting the conventional counter-argument that increased calorie intake and palatable food cause obesity rather than ultra-processed ingredients. Paul firmly rejects this premise, citing controlled feeding ward trials by Kevin Hall to argue that ultra-processed foods directly disrupt satiety cues. | |
| Canola Oil Truths and Social Media Fact-Checking | 2 | 8 | 6 | 2 | Codie asks why Paul's video on canola oil was flagged as misinformation on social media. Paul delivers a detailed breakdown of canola oil production, explaining the industrial processing of rapeseeds, chemical solvent extraction, high-heat deodorization, and plastic leaching. | |
| Sponsor Break: Riverside Content Creation Platform | 3 | 6 | 3 | 2 | Following an ad read, Codie describes her father's hypertension medication regimen and asks if pills alone are appropriate. Paul explains arterial dysregulation, metabolic dysfunction, and the conventional medical system's symptom-management approach. | |
| Medical Research Incentives and Food System Economics | 3 | 7 | 5 | 2 | Codie inquires why doctors do not scrutinize faulty nutritional studies. Paul outlines the financial constraints of the insurance model, the lack of corporate funding for saturated fat trials, and systemic groupthink around the lipid hypothesis. | |
| Hidden Toxins in Aluminum Cans and Thermal Receipts | 2 | 6 | 3 | 1 | Codie brings up her discovery that aluminum cans contain plastic linings. Paul explains the polymer barrier required to prevent aluminum leaching and connects it to dermal exposure from thermal receipt paper. | |
| Endocrine Disruptors in Cosmetics and Synthetic Fabrics | 5 | 6 | 3 | 2 | Paul explains how personal care products and synthetic workout fabrics allow endocrine disruptors to penetrate porous skin. Codie contributes industry knowledge regarding the rapid market growth of complex cosmetics and skincare among pre-teen girls. | |
| Facial Expressions, Botox Concerns, and Beauty Pressures | 5 | 5 | 4 | 4 | Codie defends the practical and aesthetic use of Botox while detailing shifting beauty standards over recent decades. Paul argues that facial freezing impairs emotional communication and mother-infant bonding, while Codie shares data on financial pretty privilege. | |
| Natural Hygiene Routines and Oral Microbiome Health | 3 | 7 | 5 | 3 | Codie questions Paul's personal hygiene practices of skipping deodorant, toothpaste, and soap. Paul justifies his routine by explaining how conventional mouthwash depletes nitric oxide producing bacteria and how synthetic soaps damage dermal microbiomes. | |
| The Impact of Hormonal Birth Control on Biology | 2 | 7 | 4 | 1 | Paul cites clinical research on how oral contraceptives alter female olfactory mate selection across the major histocompatibility complex locus. He additionally reviews observational data regarding stripper tip earnings during peak fertility windows. | |
| FDA Regulatory Loopholes and Chemical Food Additives | 4 | 7 | 6 | 2 | Codie and Paul discuss fast food ingredient lists and regulatory oversight. Paul explains the FDA's GRAS loophole compared to European chemical standards, arguing ultra-processed foods should carry graphic warning labels similar to cigarettes. | |
| Paul Saladino's Health Journey and Animal-Based Nutrition | 2 | 7 | 3 | 1 | Paul details his journey through childhood autoimmune conditions, raw veganism, strict carnivore, and his eventual transition to an animal-based diet. He explains plant defense chemicals like oxalates found in spinach and almonds. | |
| Nutritional Power of Organ Meats and Heart & Soil | 3 | 8 | 3 | 2 | Codie shares her personal experience using organ supplements, prompting Paul to explain the micronutrient profiles of organ meats compared to muscle meats. He discusses historical German research investigating organ-specific peptides and microRNA signaling. | |
| Raw Milk Benefits, Historical Context, and Satiety | 4 | 6 | 3 | 2 | Codie tests Paul with trivia about state laws regarding raw milk and describes her raw milk cleanse. Paul explains the historical transition from urban distillery swill dairies to pasteurization, alongside differences between A1 and A2 beta-casein. | |
| Additives in American and Shredded Cheeses vs Raw Cheeses | 2 | 6 | 4 | 1 | Codie asks about processed cheeses and easy health starting points. Paul explains that anti-caking cellulose and natomycin antifungals are added to shredded cheese, recommending aged raw cheeses before concluding with lifestyle guidance. |
Statements from this episode (32)
Saladino: Processed foods are killing consumers like cigarettes did
“You mean the thing that we don't quite know is killing us, but is actually killing us? Yeah, absolutely.”
Saladino: US chronic health metrics worsen despite healthier self-reported habits
“We are being counseled by our government to eat healthy, and more people will respond to surveys saying they're eating healthy, more people will respond to surveys saying they're exercising, less people are smoking, but everything is going in the wrong directi…”
Saladino: Caloric increase does not explain doubling of chronic illnesses
“I think that if you look at data, we are not really eating more calories. If, and if we're eating more calories, it's small, and it doesn't account for the increase in In all of these chronic illnesses that are just really doubling over the span of 20 or 30 ye…”
Saladino: Feeding ward studies show ultra-processed diets increase consumption
“Kevin Hall did a study, and there was recently a researcher in Japan that did kind of the same thing. They can put humans in a feeding ward where they control all of their intakes, and they present people with very similar sets of meals. One of them is ultra-p…”
Saladino: Tufts Food Compass ranked Cheerios and Froot Loops above ground beef
“Darius Mazzafarian, the same guy who gifted us with the food compass guidelines that told us that Froot Loops and Cheerios were healthier than ground beef and eggs.”
Saladino: High-erucic rapeseed oil is banned due to cardiomyopathy links
“If you just take rapeseed oil, there is a large amount of this monounsaturated fat called erucic acid in rapeseed oil, and that is linked to cardiomyopathy, heart issues in animal studies, and so it's actually banned. You cannot sell rapeseed oil.”
Saladino: 'Canola' is an acronym for Canadian oil, low acid
“Canola is an acronym for Canadian oil, low acid.”
Saladino: Plastic bottles leach cadmium, lead, and antimony into cooking oil
“So then you take all of that and you package it into a plastic bottle, which leaches cadmium, lead, and antimony into the oil, and it sits on the shelf of a grocery store”
Saladino: Proton pump inhibitors increase pneumonia risk and cause nutrient malabsorption
“You give someone a proton pump inhibitor because they have gastroesophageal reflux, right?
Well, then you have an increased rate of pneumonia because of side effects.
Then you have malabsorption of multiple nutrients, including B-twelve and other things that a…”
Saladino: No randomized controlled trials on seed oils in 50 to 70 years
“Most of them were done, in fact, all of them were done really between the late 19 fifties and the early 19 seventies. So they're all 50 to 70 years old. We haven't had a randomized controlled trial with seed oils in 50 to 70 years.”
Saladino: Aluminum cans contain an internal plastic lining
“There's a plastic bag in your aluminum can, invariably. You cannot put Any liquid in an aluminum can like that because the aluminum will leach into the fluid.”
Saladino: Touching thermal receipts absorbs endocrine disruptors through skin
“There's solid evidence that touching these receipts can lead to absorption of endocrine disrupting chemicals through your skin.”
Saladino: Eliminating conventional cosmetics cuts paraben levels 50% within days
“Women who make an intentional change to remove those things, we see noticeable, marked, statistically significant decreases in levels of these compounds in their body within a few days. Wow. It's, and we're talking like, the levels can go down by 50%.”
Sanchez: Fastest-growing cosmetic industry demographic is girls under 16
“If you look at actually the growth in the cosmetic industry in female cosmetic prop products, the number one growth is sub-sixteen years old.”
Saladino: Sweating in synthetic athleisure increases chemical absorption through skin
“Whether it's a sports bra or leggings, when you sweat in these, you can, it increases the absorption of chemicals in these pieces of clothing significantly.”
Saladino: Excessive Botox May Impair Mothers' Bonding with Infants
“There is a hypothesis that women with too much Botox could potentially impair pair bonding with their children. Because the infant is not seeing the woman's face move.”
Sanchez: Studies Show Makeup Boosts Women's Pay 15% to 30%
“There's quite a few studies that show that women who wear makeup have a double digit, we won't get that specific about the numbers, but somewhere between 15 and 30% increase In pay. Just from wearing makeup versus not. All things else being relatively equal.”
Saladino: Bad breath is caused by gut dysbiosis, not lack of toothpaste
“And if you have bad breath, it's not that you're not brushing your teeth with toothpaste, it's that you have dysbiosis in your gut, right? So it all comes back to quality of food.”
Saladino: Mouthwash kills bacteria needed for nitric oxide, reducing muscle hypertrophy
“Mouthwash, it kills all of the flora in your mouth, which are essential for the production of nitric oxide. There are studies in people who are working out in the gym that when they use to, when they use mouthwash, it actually attenuates how much muscle they c…”
Saladino: Women on birth control select mates with similar MHC genetics
“Somebody funded a study where women on birth control were given sweaty t-shirts from men, and they knew sort of the immunologic signature of the men in the t-shirts, and women on the birth control selected different mates in terms of compatibility with their g…”
Saladino: Dancers off birth control earn peak tips during ovulation
“And when the strippers off birth control are performing, they earn the most tips right around their ovulation. They have a huge peak in the month when they ovulate. And the rest of the month is like less tips, right? Women on birth control earned the same amou…”
Saladino: KFC and In-N-Out change fryer oil once a week
“I went to a KFC and an In-N-Out recently to do content, and I asked them, how often do you change the fryer oil? Which is peanut and soybean oil. They say once a week.”
Saladino: US permits up to 10,000 food chemicals compared to 500 in Europe
“In Europe, there are maybe four to 500 of these chemicals. In the United States, there are five to 10,000.”
Saladino: McDonald's french fries contain silly putty additive dimethylpolysiloxane
“Dimethyl polysiloxane, which is an ingredient in silly putty, which is in McDonald's french fries.”
Saladino: Cooking Does Not Neutralize All Plant Defense Chemicals
“There actually are defense chemicals in vegetables, and some of these can be detoxified when we cook them or when we ferment them, but not all of them, and a lot of people with autoimmune conditions do feel better when they eliminate some or all vegetables.”
Saladino: 75% to 80% of Kidney Stones Are Calcium Oxalate
“75 to 80% of kidney stones are calcium oxalate kidney stones, and dietary oxalate can be a major contributor to that.”
Saladino: Muscle meat lacks copper, folate, and biotin found in liver
“If you just look at muscle meat, high in B-II, high in zinc, high in iron, not a lot of copper, not a lot of folate, not a lot of biotin. Liver has all that stuff. Liver has copper, which balances zinc.”
Saladino: Consumed animal organs biologically target and support corresponding human organs
“What you see is there's a lot of evidence that Oregon's Do support the corresponding organ in humans, which really breaks the mind of a traditionally trained doctor like myself. So when you give we can take an embryo, for instance, and you put a little bit of …”
Sanchez: Raw milk is illegal in more US states than silencers
“There are more states where raw milk is illegal than silencers, which I thought was interesting.”
Saladino: Studies link raw milk consumption to lower allergy and asthma rates in kids
“There are specific studies looking at lower rates of asthma, eczema, and allergies, the things I suffered from, but didn't drink raw milk growing up, in kids who drink raw milk, whether they grow up on a farm or off a farm.”
Saladino: Raw cheeses aged over 60 days contain virtually zero lactose
“There are a number of raw cheeses that are fermented for more than 60 days that have essentially no lactose.”
Saladino: A Meat and Fruit Baseline Helps Resolve Health Issues
“If you have health issues, think simple. Start maybe with meat and fruit, and then see if the health issues get better over time, and then add things back gradually. And that's just, I think, a good starting point for people as a framework, as a blueprint.”