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WTF Opinion
Chouksey: Blue Zones Do Not Exist and Rely on Cherry-Picked Data
“Personally, I'm not very convinced on the idea of blue zones. There's a lot of data out there which suggests that blue zones are created. They don't exist. So classic case of cherry picking. And so what they have done is they have mapped certain groups of popu…”
Jitendra Chouksey Feb 2, 2025 ▶ 3:37 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Prediction Not checkable as stated
Chouksey: Most Indian Cities Will Be Uninhabitable Within 5–10 Years
“I think next five to 10 years, most of the cities in India, well, as per WHO would be, you know, uninhabitable. When it comes to AQI and water quality”
Jitendra Chouksey Feb 2, 2025 ▶ 1:43:25 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Supported
JC: No data suggests continuous glucose monitors help non-diabetics
“CGM, again, I'm not a huge fan of CGM. It's great for diabetics, but in non-diabetics, there's no data that suggests it helps non-diabetics. I mean, apart from making people feel scared of every single food on the planet that spikes their blood glucose, and yo…”
Jitendra Chouksey Feb 2, 2025 ▶ 2:38:08 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Supported
Chouksey: Andrew Huberman has a conflict of interest through an AG1 investment
“So, Huberman also has a conflict of interest, because AGI promises they have all of these things, and Huberman has an investment in AGI.”
Jitendra Chouksey Feb 2, 2025 ▶ 3:00:02 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Opinion
Chouksey: Fittr has no competitive moat except for its community
“Actually, at this point, to be very honest, except for the community, nothing.”
Jitendra Chouksey Feb 2, 2025 ▶ 1:49:37 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Opinion
Chouksey: Bryan Johnson's experimental therapeutics are mostly unvalidated and shouldn't be preached
“What I have problem with is some of the experimental therapeutics, the hundred pills and everything. Most of these things are unvalidated. So as long as he's keeping those experiments in check and he's doing it on himself, As a science experiment? Good. I'm ju…”
Jitendra Chouksey Feb 2, 2025 ▶ 2:14:32 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Partly supported
Chouksey: Second Opinion survey found 41% of recommended surgeries were unnecessary
“There was this company called Second Opinion. And they found out, they did a survey, and they found out that almost 41% of the surgeries were unnecessary.”
Jitendra Chouksey Feb 2, 2025 ▶ 2:26:55 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Contradicted
Chouksey: All Shilajit research studies are corporate-funded by PrimaVie
“All Shilajit studies are funded by the company that makes Shilajit formulation, Prima V.”
Jitendra Chouksey Feb 2, 2025 ▶ 2:44:26 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Contradicted
Chouksey: Indian whey protein brands only import and rebrand raw material
“Because even if we talk about whey protein, it's not that we have whey protein companies in India, you know, like besides Amul, I don't think they're just importing. We are importing everything. And when it comes to whey protein, we're just mixing stuff, label…”
Jitendra Chouksey Feb 2, 2025 ▶ 2:51:29 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Not checkable as stated
Chouksey: Fasting is no better than a standard calorie deficit
“In fact, fasting is no better than just being in a state of calorie deficit.”
Jitendra Chouksey Feb 2, 2025 ▶ 3:05:23 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Contradicted
JC: No proof NAD precursor supplements reach the mitochondria
“But if you're talking about taking supplements that are working at a mitochondrial level, it doesn't have any proof. It doesn't have any validation. For example, if we talk about NAD precursors, Today, we don't know if those precursors are actually getting abs…”
Jitendra Chouksey Feb 2, 2025 ▶ 32:38 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Partly supported
Chouksey: Blood tests for magnesium are misleading due to bone mineral leaching
“A lot of people rely on blood tests for magnesium, which is not the right way. You should rely on you know, DEXA for that. So, because over a period of time, body's homeostasis would leach out magnesium and other minerals from your bones and still maintain you…”
Jitendra Chouksey Feb 2, 2025 ▶ 1:25:02 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Opinion
Chouksey: Insurance hazard ratio modeling is 20 years outdated
“Today insurance companies spend a lot of people in assessing hazard ratio. Some of the things are very straightforward, but some of the, it's not a, how do you say, it's not a nuanced approach. They are still following the same approach for, you know, arriving…”
Jitendra Chouksey Feb 2, 2025 ▶ 2:08:59 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Partly supported
Chouksey: Alcohol contains DNA-damaging formaldehyde and causes cellular harm
“Alcohol has formaldehyde. Pomaldehyde has the potential to damage your DNA. So at a cellular level, it is damaging.”
Jitendra Chouksey Feb 2, 2025 ▶ 2:12:25 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Opinion
Chouksey: Practo is an uncurated listing platform, not a quality service
“Yeah, I don't think Praktu is curated. They're more of a listing platform.”
Jitendra Chouksey Feb 2, 2025 ▶ 2:25:53 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Partly supported
JC: Whoop samples heart rate more frequently and accurately than Apple Watch
“For example, again, you have Apple watch, for instance, they don't sample your heart rate as frequently as let's say a whoop. So in terms of sampling whoop has the highest sampling rate and that's why it's most accurate.”
Jitendra Chouksey Feb 2, 2025 ▶ 2:36:11 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Partly supported
Chouksey: Oral collagen supplements do not increase collagen production
“So you taking collagen supplementation is not going to in any way, meaningfully increase the production of collagen.”
Jitendra Chouksey Feb 2, 2025 ▶ 2:46:07 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Opinion
JC: Rapamycin Provides No Added Benefit If You Exercise and Eat Protein
“If somebody is not working out and not eating enough amount of protein, they can benefit from taking rapamycin. But if you are working out and you feel taking adequate amount of protein, no difference.”
Jitendra Chouksey Feb 2, 2025 ▶ 2:53:56 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Supported
JC: Growth Hormone Use Can Cause Heart and Organ Enlargement
“One of the side effects of growth hormones is growth of other organs, which is the unintended consequences. Let's say you take growth hormones to improve your muscle hypertrophy. Now, heart is also a muscle. So people observe megaly in their heart, right? So h…”
Jitendra Chouksey Feb 2, 2025 ▶ 2:57:55 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Supported
Chouksey: PRP therapy effectively stimulates hair follicles and roots
“It works. It helps because it's basically stimulating your hair follicles and basically nourishing your hair roots with you know, like plasma rich blood.”
Jitendra Chouksey Feb 2, 2025 ▶ 3:09:17 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Not checkable as stated
Chouksey: Indian health AI will fail without local training datasets
“Today, India does not have quality data sets, and somebody will have to figure out. Either they create their own personalized labs, work with wearable companies like us, or work with hospitals. But we need trainable data sets. Without trainable data sets, our …”
Jitendra Chouksey Feb 2, 2025 ▶ 3:14:21 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Assertion Supported
JC: CALERIE Trials Prove Sustained Caloric Deficit Improves Mitochondria
“We have the calorie one, calorie two the whole calorie trials. And then we also have lots of studies, which have proven that calorie deficit, a slight calorie deficit over a period of time results in improved mitochondrial efficiency”
Jitendra Chouksey Feb 2, 2025 ▶ 2:55:26 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
WTF Disclosure
Chouksey: I am not taking any health supplements
“I can go on record and tell you guys, I'm not taking anything.”
Jitendra Chouksey Feb 2, 2025 ▶ 2:39:52 Ep #21 | WTF is Longevity? | Nikhil ft. Nithin Kamath, Bryan Johnson, Prashanth, Jitendra & Seema · Nikhil Kamath
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