People, every show

Dave Burke

Advisor, Arc Institute. On 1 show, 1 appearance. The Shows tab opens the full record on each.

executiveengineerfounder@davey_burke ↗LinkedIn ↗arcinstitute.org ↗

Dave Burke spent 14 years at Google, serving as Vice President of Engineering for Android and overseeing OS and Google Pixel software as Android scaled to over 3.5 billion devices. In 2024, he joined the biomedical nonprofit Arc Institute as its inaugural CTO to lead computational technology before transitioning to an advisory role.

What they said5 Shows1

Everything Dave Burke said on any show that made the record, most notable first. Each card names its show and opens the statement there.

NO PRIORS Assertion Not checkable as stated

Burke: Current virtual cell models have only around 10% predictive accuracy

“The reality is today the best models are very poor at this. like the predictive ability of the DEGs as we call them is, is in the order of 10%.”

Dave Burke Feb 25, 2025 ▶ 33:19 No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute

NO PRIORS Opinion

Burke: Virtual cell accuracy is limited by data quality, not architecture

“One of our conjectures is that one of the reasons the models aren't doing well is not just simply model structure. We have a lot of rich structures that we understand in the ML space and machine learning space that the issue is the Data quality.”

Dave Burke Feb 25, 2025 ▶ 33:38 No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute

NO PRIORS Disclosure

Burke: Arc Institute built SC Basecamp with 230M single cells

“We've created something called SC Basecamp and you can almost think of it like the Google crawler and index, so we've built this agent that goes onto the internet, And basically mines public single cell sequenced RNA data, and then curates it in a very sort of…”

Dave Burke Feb 25, 2025 ▶ 27:51 No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute

NO PRIORS Insight

Burke: Transcriptomic level is the right abstraction for cell modeling

“And so I think our belief around the room is the right level of abstraction is at the sort of transcriptomic level because you have these very complex gene pathways. And so whenever a cell is changing to its environment reacting, that it will be reflected and …”

Dave Burke Feb 25, 2025 ▶ 41:59 No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute

NO PRIORS Assertion Supported

Burke: Evo 2 trained on 9.3 trillion nucleotides predicts BRCA1 pathogenicity

“Like, if you look at the EVO II model, we trained it on 9.3 trillion nucleotides, but we didn't tell it anything about DNA. We just like, here's a lot of DNA on the planet across, you know, every single piece of DNA we could get a hold of. And then what di…”

Dave Burke Feb 25, 2025 ▶ 54:27 No Priors Ep. 103 | With Vevo Therapeutics and the Arc Institute

One line per show, most statements first. The link opens Dave's full record on that show: the calibration, argument clarity, speaking style and every statement made there.

Show	Role there	Eps	Statements	Record
NO PRIORSLEDGER	Advisor, Arc Institute	1	5	100% 1/1	full record on No Priors →