MRNA

topic on 2 shows · 4 statements across 2 episodes

the a16z Podcast How I Built This

4 statements about MRNA, every show

a16z Assertion Supported
Bancel: Moderna mRNA delivers directly to lymph nodes and immune cells
“With all technology, I cannot speak about all the mRNA companies that have different mRNAs, different lipids, and so on, but with all technology, when we inject our mRNA in a muscle, whether it's a COVID shot, a flu shot, or this cancer treatment, basically th…”
Stéphane Bancel Sep 2, 2026 ▶ 12:02 Inside Moderna’s Biggest mRNA Test Since COVID
a16z Disclosure
Bancel: Moderna prints 34 cancer mutations into individualized vaccines in 30 days
“We select the 34 that we believe are the most relevant, and we stitch them together into one big mRNA molecule, which we make in thirty-ish days for you, that is injected then in a hospital intramuscularly.”
Stéphane Bancel Sep 2, 2026 ▶ 14:08 Inside Moderna’s Biggest mRNA Test Since COVID
HOW I BUILT THIS Assertion Not checkable as stated
Afeyan: Nobody took mRNA research seriously as recently as 2016
“Five years ago, nobody was taking MRNA research seriously”
Noubar Afeyan Oct 11, 2021 ▶ 36:23 Moderna and Flagship Pioneering: Noubar Afeyan
Afeyan: Precision in guessing what works is unimportant when pioneering new fields
“The accuracy with which you have to guess what's going to work Is not at all important. Because we get into these brand new areas, it's wide open to find where value lies, right? Imagine if we waited three, four years as people did, or 10 years in the case of …”
Noubar Afeyan Oct 11, 2021 ▶ 44:00 Moderna and Flagship Pioneering: Noubar Afeyan

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