Melatonin
topic on 2 shows · 4 statements across 2 episodes
the Knowledge Project 
the Paul Morris Podcast
4 statements about Melatonin, every show
Kuno: 95% of human melatonin is produced in mitochondria
“95% of melatonin is made in our mitochondria, and it's an anti-inflammatory.”
Huberman: 15 seconds of bright nighttime light drops melatonin to zero
“Light viewed by the eyes inhibits melatonin, so much so that if melatonin levels are at their peak and you walk into the bathroom at night and you flip on the lights and it's really bright, if you spend more than 10 or 15 seconds in that light, your melatonin …”
Huberman: Seasonal Light Changes Dictate Melatonin Release Levels
“Remember, light inhibits melatonin. The longer the day, the shorter the melatonin signal. So in summer months, your body releases very little melatonin. In winter months, because days are shorter and there's less light overall, you release much more melatonin.”
Huberman: 1mg Melatonin Is ~100x Natural Secretion and Suppresses Puberty
“What you take in terms of one milligram melatonin, very small dosage, something like a hundred times what you naturally secrete. I get really concerned about this, especially in kids because melatonin is actually the hormone that suppresses the onset of pubert…”