gene therapies

5 statements across 4 episodes · 4 bullish · 1 bearish · 4 people on the record · first statement Jan 17, 2019 by Vas Narasimhan · across every show →

Everything said about gene therapies, oldest first

Jan 17, 2019 bullish
Insight
Narasimhan: AAV vectors enable reusable platform delivery in gene therapy
“When you think about AAV vectors, these are ways to deliver these gene therapies into the body. Once you solve it, the process, let's say for one of these vectors, you can apply it to multiple different diseases and not have to Recreate everything again. That'…”
Vas Narasimhan Jan 17, 2019 ▶ 31:13 a16z Podcast | The Science and Business of Innovative Medicines
Apr 1, 2019 positive
Insight
Church: Regulators favor breakthrough therapeutic platforms over incremental updates
“To some extent, I think they like new technologies more than they like the old ones. The old ones tend to fail because they're so incremental that they're no longer compared to the placebo, they're compared to whatever they're in increment over, whatever thera…”
George Church Apr 1, 2019 ▶ 13:39 a16z Podcast | What's in the Water at the George Church Lab?
Oct 5, 2019 bullish
Assertion Supported
Andy Tran: Gene therapy startups drove major biotech exits
“In fact, taking a look at the past several years, some of the largest biotech exits have been from companies developing these gene therapies.”
Andy Tran Oct 5, 2019 ▶ 2:47 CRISPR 2.0 and the Future of Gene Therapies
Oct 5, 2019 positive
Assertion Supported
Tran: 24 gene therapies slated for Phase 3 trials in 2019
“There are about two dozen more gene therapies that are slated to just have phase three trials in this year alone.”
Andy Tran Oct 5, 2019 ▶ 2:11 CRISPR 2.0 and the Future of Gene Therapies
Jan 6, 2020 bearish
Prediction Not checkable as stated
Abernethy: Manufacturing consistency will be a major hurdle for gene therapies
“Manufacturing, I think, starts to become more and more of an issue across this space.”
FDA Chief Information Officer Jan 6, 2020 ▶ 18:05 Food, Drugs, and Tech: 100 years of Public Health
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