Vas Narasimhan, CEO of Novartis, highlights how gene therapies move pharmaceutical manufacturing away from bespoke, per-medicine processes to modular platforms.
Assertion Not checkable as stated
AI outperforms internal human analysts at forecasting Novartis product sales
“The other area, interestingly, in the financial area as well, we find that AI does a great job predicting our free cashflow, predicting a lot of our sales for key products, and it does better than our internal people because it doesn't have the biases and the …”
Prediction Open · timeframe Jan 2039
Viable animal-to-human organ xenotransplantation will arrive within 10 to 20 years
“I think a couple of things will likely come. I think xenotransplantation, I mean, which has been in and out and worked on. And what's interesting is every one of these comes up and down. So, you know, gene therapies, cell therapies popped up in the nineties, k…”
Opinion
AI in digital health currently offers very little actual impact
“Well, I have to first say, I completely agree about the hype cycle here. I mean, as we've gotten quite scaled and working on digital health and data science, we've learned that there's a lot of talk and very little in terms of actual delivery of impact.”
Opinion
Real-world evidence cannot replace randomized blinded clinical trials
“The other thing people talk about, but I mean, I'll take a skeptical voice around it, is the ability to use real world evidence to try to get at these things. But as somebody who's worked in clinical trials for most of their time in, in the industry I do belie…”
Assertion Not checkable as stated
Wearable sensors have failed to meet clinical trial validation standards
“When I think about, first of all, I would say just in general in sensors is another place where there's been a lot of hype Above what, of expectations. I mean, we've been really trying to explore the use of sensors in clinical trials now for, in my own experie…”
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Pharma clinical trial success rates have stayed flat at 5 percent
“And actually, when you look at attrition rates in our industry, really the chances of success that we have, they haven't moved in the last 15 years. Still, when we bring a medicine into human beings, on average, only one out of 20 works.”