psilocybin

“So six of them, they were still well after six months. Three of them, it didn't work. And then for 11 of them, and this is, ah, yes, the majority of them, they were really well for three months, depression-free or very mild symptoms of depression. But then aft…”

“On a 10 milligram dose you would see, tend to see more psychodynamic stuff, so internal exploration. People feeling more emotional, feeling that they maybe get some insight into different parts of their life. And often there's struggle because the amount of ps…”

“So of our 20 well, the first thing to say is that they all said that they would prefer it to any other treatment they tried.”

“It seems to, for most people last for about two or three months and then the depression starts to come back.”

“So they, this, the study that I have, was involved in was a clinical study looking at 20 people with treatment resistant depression, and it was the first study of its kind in the UK”

“With 10 milligrams, it opens it a little bit. And so the things come out and you might be having a conversation with a dead parent, or you might be thinking about a relationship that ended and It's like a very intense turbocharged therapy session, but you can …”

“Psilocybin is not nearly as effective if you're on antidepressants. It really takes the I mean, it takes the highs and the lows. Yeah, yeah, exactly. Yeah. It stops it from working, essentially.”

“With psilocybin it's completely different because the expert is themselves. They are the expert because what's happening, the healing power of this is something in the unconscious mind, their own unconscious mind is writing itself. There's a homeostatic princi…”

“And the key finding was that psilocybin seems to deactivate the part of your mind or brain that is responsible for ruminating, for negative thinking on a loop.”

“So our next study, we're going to be looking at psilocybin versus antidepressants. We're going to be comparing them.”

“In the last study there was a low dose and a high dose session. The low dose session was 10 milligrams, and the high dose was 25, and they look pretty different, these sessions.”