Q So first in history opportunity for, um, scientists and entrepreneurs to go work on this dataset and create these virtual cell models. How do you tell the quality of one of these models?
A I mean, the, I mean, the core idea is it's what's its predictive ability, right? And so, you know, you, you take a cell, you perturb it, you can, you can do that either by, you know, from a genetic perspective, you can, you can suppress or, or, or, uh, upregulate genes and then, or, or apply drugs, and then you look at the response. And so the, the measure of the model is how well it predicts the, what we call the, the differentially expressed genes. Um, the, the reality is today the, the best models are, Um, very poor at this. Um, like the, the, the predictive ability of, of the DEGs as we call them is, is in the order of 10%. Um, and one of the conjectures.
AI assessment note: “the measure of the model is how well it predicts the, what we call the, the differentially expressed genes.”