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Verbatim, from the transcripts: the passages where ESMC comes up

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🔬 The Bitter Lesson is Coming for Proteins - Alex Rives, BioHub May 27, 2026 · 18 mentions

  • ▶ 0:00 Alex Rives So ESMC is all, is also approaching programmable biology, but I would say in a very different way. 3 times in the scene
  • ▶ 10:22 Alex Rives So, I mean, basically what we've done is we've trained sparse auto encoders across all the different layers of the ESMC model family. 2 times in the scene
  • ▶ 16:24 unnamed speaker I think that ESMC in particular has some new data sources compared to like previous models, which might be helpful. 9 times in the scene
  • ▶ 26:02 unnamed speaker I mean, did you just end up saying, like, okay, let's make C bigger, and then suddenly it worked, and now you learned that actually we don't need priors anymore? 4 times in the scene
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