The Ledger, every show
Every statement that passed quotation and attribution checks, across all 44 shows. Pick shows below, then mix any filter with any other.
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every show 44 of 44
Topol: Personalized vaccines are curing pancreatic and kidney cancers
“So vaccines now are capable Of cures of pancreatic cancer, kidney cancer, with these personalized vaccines using the proteins of the person's tumor.”
Topol: Mass screening detects only 14% of cancers despite massive costs
“We only pick up 14% of cancers from that mass screening, which costs over hundreds of billions of dollars a year.”
Topol: Age reversal therapies like senolytics remain unproven in humans
“Where you get reversing of aging, so you keep people healthier body-wide, and that's where we see all this remarkable investments in companies like Altos and with reprogramming, Senolytics, and a long list. But they're really focused on a monumental task, whic…”
Topol: Lifestyle changes can prevent up to 90% of cardiovascular disease
“They, ah, are preventable variably, so cardiovascular, 80 and 90% from lifestyle and related factors, modifiable factors, like your LDL cholesterol, that kind of thing.”
Topol: Lifestyle factors can prevent 50% of cancer and neurodegenerative diseases
“And cancer and neurodegenerative, just from what we know today with lifestyle factors, we're about half that can be prevented.”
Topol: B-cell depletion resets the immune system to cure autoimmune diseases
“In the last couple of years, we've seen Unprecedented cures. We never had anything. Lupus. Progressive systemic sclerosis. Even cases of multiple sclerosis. Dermatomyositis. So, basically, it's depletion of all the B cells, and when they come back, they have f…”
Topol: AI biomarker models can predict Alzheimer's onset decades early
“For example, with Alzheimer's, you get a P-Tau, two 17. It's modifiable by lifestyle. You check it again in, you know, six months or a year. Now you have two data points, and you can say, you know, with all the other data that's available, when you're gonna se…”
Scripps will run a GLP-1 trial for non-overweight long COVID patients
“We're gonna be doing a long COVID trial in people who are not overweight.”
Topol: At least half of patients regain weight after stopping GLP-1s
“We don't have encouraging data at the moment, because at least half of people gain weight back when they stop.”
Topol: P-tau protein testing provides 20-year warning for cognitive impairment
“We can also look at specific proteins, like, for example, For the brain, p-tau- . And what's amazing about that protein, which we can get now, and it's not that expensive, but that in itself gives us over a twenty-year warning about mild cognitive impairment.”
Topol: Lifestyle modifications can reduce p-tau protein levels up to 80%
“It's modifiable by exercise and lifestyle. We've seen people in studies that drop more than 50%, even up to 80%.”
Scripps study finds little genomic explanation for healthy aging to 87
“We had done a big study we called the Welderly, where we basically found very little in the genomes of people who had gone to the age of 87 on average with never having had an age-related disease.”